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Biomedical subjects

G Jenny

Publications and source records attributed to G Jenny.

At least 19 recordsLinked to original sources

Preservation of anterior cruciate ligament in total knee arthroplasty.

Few prostheses allow preservation of the anterior cruciate ligament (ACL) during total knee replacement. We report a short-term, prospective, open study of 32 ACL-retaining and 93 ACL-replacing total knee replacements and compare the respective outcomes of both prosthesis types with a follow-up time of 2-3 years. Mean operative time, complication or revision rates did not differ, nor did the early and late clinical and radiological evaluations. This study does not support the suggestion that technical difficulties increase for ACL preservation. The clinical and functional results were neither improved nor worsened for ACL-retaining prostheses. There is thus no advantage, but also no inconvenience, in retaining the ACL according to short- to mid-term results of a gliding posterior cruciate ligament (PCL)-retaining prosthesis with ACL-replacement design. The possibility of an improved long-term outcome of an ACL-retaining prosthesis should be investigated further.

Adult↗

[Long-term survival rate of tibial osteotomies for valgus gonarthrosis].

PURPOSE OF THE STUDY: High tibial osteotomy (HTO) is a routine procedure for medial gonarthrosis. Mid-term results are known to be satisfactory, but they deteriorate with longer follow-up. The authors present a long term survival analysis of 109 out of 111 consecutive HTO with a minimal potential follow-up of ten years. MATERIAL AND METHODS: 111 patients were consecutively operated on for isolated primary varus gonarthrosis between 1977 and 1985: 57 men and 54 women, with a mean age of 53 years (range, 27 to 79 years). X-ray measurements were done on stance, hip-ankle view. Global axial deformation was defined as the angle between mechanical axes of femur and tibia. The respective part of congenital and degenerative tibial deformation was assessed according to Dejour. The angle between femoral and tibial bicondylar lines, representing lateral instability, was added to the tibial degenerative deformation to represent the total degenerative deformation. The goal of correction was a 3 to 7 degree mechanical valgus angulation. At the time of bone healing, 82 patients (74 per cent) had an optimal correction. Two patients were excluded from the follow-up study because of a severe complication (1 bacterial arthritis and 1 tibia non union) which could interfere with the long term result. The 109 remaining patients were followed for a minimal period of 1 year (mean: 8.4 years). GUEPAR pain grading and the occurrence of a revision were prospectively analyzed. 57 non reoperated patients could be re-examined at a mean maximal follow-up of 13.5 years (range, 10 to 18 years). Failure was defined as either the occurrence of a grade 2 or 3. GUEPAR pain during the whole follow-up, or a clinical or functional Knee Society score < 80 points at final follow-up, or revision. Failure and revision rates were calculated according to Kaplan and Meier. RESULTS: 11 patients were reoperated on before final examination (10 per cent): 2 medial unicondylar and 9 total knee prostheses. At final follow-up, the mean clinical and functional scores were respectively 87.0 points (range, 24 to 100 points) and 86.3 (range, 45 to 100 points). The cumulative failure rate was 33 per cent after 10 years and 54 per cent after 15 years; the respective revision rates were 9 per cent and 19 per cent. A pre-operative total degenerative deformation superior to 3 degrees led to a 3.5 fold increased failure rate (p < 0.000,1). A pre-operative medial joint space narrowing over the half of the normal, lateral one led to a 2.2 fold increased failure rate (p = 0.014). An optimal post-operative correction led to a 3.2 fold decreased failure rate (p = 0.000,1). For a given total degenerative deformation, patients with a congenital deformation superior to 5 degrees had a significant lower failure rate (p < 0.000,1). No factor significantly influenced the revision rate. DISCUSSION: Ideal patients for HTO, with an expected survival rate of 100 per cent after 13 years, have moderate degenerative changes and a congenital deformation superior to 5 degrees. Patients with advanced degenerative changes and no congenital deformation experienced a 35 per cent failure rate after 10 years. In this population, unicondylar replacement should be considered as a valuable alternative.

Adult↗

Elevation of the tibial tubercle for patellofemoral pain syndrome. An 8- to 15-year follow-up.

One hundred patients were operated on by the Maquet procedure for chondromalacia patellae. All of them were first re-examined after a mean follow-up of 4 years, and 65 of them re-examined after a mean follow-up of 11 years (range, 8-15 years). The pain score improved significantly after the operation and remained unchanged with longer follow-up. The success rate was only 62% at both follow-ups. Outerbridge grade IV chondral lesions at the time of surgery were associated with a significant improvement of the pain score at the 4-year follow-up and a success rate of 69%. The Maquet procedure should only be proposed for chronic retropatellar pain with grade IV chondral lesions, after conservative treatment has proven unsuccessful, as the expected failure rate is about 30%.

Adolescent↗

Utility of measurement of gentamicin release from PMMA beads in wound drainage fluid after in-vivo implantation.

Acute or chronic osteomyelitis in 188 patients was treated by surgical debridement and filling of the cavity with gentamicin-PMMA beads. The gentamicin concentration was measured in the total drainage fluid of the first postoperative day. There was no correlation between this concentration and the amount of implanted beads. It is impossible to predict preoperatively the gentamicin concentration which will be obtained in situ. The measurement of gentamicin concentration in the total drainage fluid of the first postoperative day and its comparison to the minimal bactericidal concentration of responsible pathogens, allow very early assessment of the effectiveness of the local antibiotherapy and if necessary, adaptation, of systemic antibiotherapy.

Exudates and Transudates↗

[Risk of infection in centro-medullary locking nailing of open fractures of the femur and tibia].

Intramedullary reamed locking nail of open fractures remains controversial because of the risk of infection. 1,474 closed reamed locked nailings were performed between 1974 and 1989 for femoral (744 cases) or tibial (730 cases) fractures. 349 fractures were open: 100 femoral fractures (51 Gustilo and Anderson Grade I and 49 Grade II) and 249 tibial fractures (140 Grade I, 99 Grade II et 10 Grade III). 24 femoral (3.2%) and 46 tibial (6.3%) nails were followed by infection. This difference is significant (p < 0.01). Reoperations for infection occur more frequently for femoral than tibial fractures (p < 0.05). There is no difference between the results of infection treatment between femoral or tibial fractures. Traumatic opening of the femoral fracture site does not affect the occurrence of an infection, its severity or the results of its treatment. Traumatic opening of the tibial fracture site significantly increases the infection rate (p < 0.001), and the incidence of infection increases with the severity of the soft tissue lesions; but the severity of the infection and the results of its treatment are not modified. Acute closed reamed intramedullary locking nail is the best treatment for open femoral or tibial fractures with respect to the bone healing and infection rate for Grade I and II fractures. For Grade III fractures, nailing must be followed by a coverage flap.

Femoral Fractures↗

Infection after reamed intramedullary nailing of lower limb fractures. A review of 1,464 cases over 15 years.

We studied 1,464 consecutive immediately-reamed intramedullary locked nailings of tibial or femoral fractures. There was an increase in postoperative infection if the tibial fracture was open; the relative risk increased with the severity of the soft tissue lesion. There was a marginal increase in the postoperative infection rate for open femoral fractures. A comparison of these figures with those in other methods of treatment and the mechanical and clinical advantages of nailing leads us to propose this method of treatment for Grades I and II open fractures of the femur or tibia.

Bone Nails↗

[Intermediate results of the replacement of the anterior cruciate ligament with 3 types of dacron prostheses].

We have replaced the anterior cruciate ligament in 92 patients using Dacron prostheses. There were 52 Stryker implants, 25 Leeds-Keio and 15 Proflex. The majority of the patients were active sportsmen. A similar operative technique and postoperative programme was used in each patient. Seventy patients have been re-examined, and a further 9 answered a postal questionnaire. Forty Stryker ligament repairs have been followed up for an average of 28 months; 15 had broken or were otherwise inadequate. Ten patients had symptoms and there were 4 re-operations. Of the Leeds-Keio repairs 20 have been reviewed, of which 7 were either ruptured or mechanically inadequate. Three patients had symptoms and 1 had undergone further operation. Of 14 Proflex ligaments, 1 had failed, but the patient was asymptomatic. The authors consider that the Stryker and Leeds-Keio ligaments should not be used, and that the Proflex prosthesis shows promise but requires long term assessment.

Adolescent↗

[Cardiac arrest caused by pericardial heart dislocation].

A case is reported of a 33-year-old multiple injured patient with closed chest trauma and an unknown rupture of left pericardium and hemidiaphragm. A peroperative cardiac arrest, one year later, was related to dislocation of the heart. Thoracotomy for internal cardiac massage was responsible for a successful outcome.

Adult↗

[Value of the assay of C-reactive protein in osteoarticular infection].

The C-reactive protein is specifically increased in the acute phase of inflammation. Its level in the serum is measured by the use of immunonephelometry and is obtainable after 2.5 hours. It normally ranges between 3 and 22 mg/litre. The authors have measured the C-reactive protein after 50 surgical procedures in septic cases. They have compared its levels with other biological tests such as the sedimentation rate and the leucocyte count. The variations in C-reactive protein occurred very early and were very extensive, the increase ranging between 200 and 1500 per cent after the surgical procedure. In cases without septic complications the level returned to normal within seven days, while the sedimentation rate only became normal after three months. In cases with septic complications, the rise of C-reactive protein appeared before clinical signs. Therefore, such an increase should lead to a search for a persistent infective focus or the presence of an osteitis. However, this biological test cannot differentiate between an acute infective and a severe inflammatory process.

Arthritis, Infectious↗

[Psychic hospitalism in patients confined to bed for long periods of time in the septic ward for posttraumatic osteomyelitis].

It has to be emphasized that the reconstruction of the soft tissue cover of the lower leg is an important procedure. Plastic surgery has to be performed primarily. Otherwise the consequences beside multiple procedures are a very long hospitalization. In this connection, the evaluation of patients shows very grave psychological changes and difficulties in regard to social rehabilitation.

Bed Rest↗

[The use of sulphan blue dye during surgical procedures for bone infection].

Sulfan blue is a vital dye which can be injected intravenously before a surgical procedure and produces a greenish coloration of all vascularised tissues. The authors describe the technique of its use and its toxicity. This technique makes it possible to recognize during an operation all devitalised tissues and to excise them with greater accuracy.

Bone Diseases↗

[External rotational instability of the knee].

Among cases of recent or long-standing post-traumatic laxity of the knee ligaments, unstable lateral rotation is due to a well-defined anatomical lesion, viz. Rupture of the medial capsular ligament of the knee. This laxity is demonstrated clinically by the existence of an abnormal postero-anterior movement when the tibia is in lateral rotation. Its surgical treatment, suggested by D. Slocum, consists of displacement of the patella tendon. This rupture may exist alone but, usually, is associated with other ligamentous or meniscal lesions for which further specific treatment should be carried out. Slocum's operation has recently been used in the Strasburg Accident Centre. The early results are encouraging.

Adolescent↗