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Biomedical subjects

G Juvarra

Publications and source records attributed to G Juvarra.

7 recordsLinked to original sources
PubMed1985

Successful treatment of subacute cerebellar degeneration in ovarian carcinoma with plasmapheresis. A case report.

Subacute cerebellar degeneration is a rare complication of some neoplasms, and is generally resistant to therapy. A case of subacute cerebellar degeneration in a 50-year-old woman with a Stage II grade 3 serous ovarian adenocarcinoma is reported. The onset of the neurologic symptoms preceded the diagnosis of cancer and progressively worsened during and after four cycles of chemotherapy. A quick, partial improvement of the neurologic syndrome was documented after three weekly treatments with plasmapheresis. The contribution of circulating factors in inducing subacute cerebellar degeneration can be postulated. A trial using this new type of treatment should be performed in patients who have this therapeutically refractory clinical condition.

Acute Disease↗
PubMed1985

Hypercalcemic encephalopathy in the course of hyperthyroidism.

A hypercalcemic condition can be observed in association with hyperthyroidism. The case of a patient suffering from hypercalcemia and hyperthyroidism is reported. A confusional state and EEG alterations, among which diffuse monomorphic delta rhythms were remarkable, are shown. As soon as normalization of calcemia was achieved, a rapid clinical and EEG improvement took place. A hypothetical interpretation is proposed, according to which a prolonged, though inconstant, and mild hypercalcemia in the course of hyperthyroidism could determine an encephalopathy, concealing in some way thyrotoxic symptoms.

Brain Diseases↗
PubMed1978

Studies on the etiology of the experimental neuropathy from industrial adhesive (glues).

Chickens treated by paintbrushing with glue distillate (used in shoe industries), hydrocarbon mixture and TOCP in hexane, developed paralysis (4/5); in these, we have demonstrated a diffuse degeneration of the myelinic sheath of the peripheral and central neurites. Besides TOCP, cyclohexane (because of its higher concentration in the glue distillate and in the hydrocarbon mixture) may be indicated as responsible for occupational neuropathy.

Adhesives↗
PubMed1977

[Petit mal status].

The historical evolution of P.M.S. nosography is pointed out, and his clinical features are exposed, mainly on the ground of the study performed by Lob and Coll., for the Tenth Marseilled Colloquium. Stress is laid upon the onset age of P.M.S., making reference to a review of 133 cases previously reported in the literature. Two paradigmatic cases are reported, selected between six P.M.S. observations we collected, and electroclinically investigated, from 1972 to 1975: a woman aged 34 who was suffering from P.M. and G.M. seizures since she was 12-years old, and also had some other P.M.S. episodes during past years; a woman aged 45 who suffered from a sudden P.M.S. attack, during a febrile illness: it seemed that it was the first occurrence, but an accurate catamnestic search suggested that previous P.M.S. manifestations had probably occurred during the infancy. Finally P.M.S. nosography is discussed for what concerns the variable features emphasized by our observations, the correlation between P.M. and P.M.S., and the problem of P.M.S. as the sole epileptic phenomenon.

Adult↗
PubMedDate not supplied

[Idiopathic orthostatic hypotension: Shy-Drager's syndrome (author's transl)].

The authors report a clinical case of idiopathic orthostatic hypotension with associated signs of focal cerebrovascular lesion. They discuss aetiopathologic hypotheses which have been proposed to interpret pathological situations of this type. It seems reasonable to attribute an autonomous disease classification to idiopathic orthostatic hypotension as a systemic degenerative disease concerning peripheral and central structures with vegetative functions. The Shy-Drager syndrome (idiopathic orthostatic hypotension associated with diverse signs of involvement of the central nervous system) must not, however, be considered as an independent form of disease. The associated signs are none other than the expression of commonly found cerebral ischemic lesions deriving from abrupt arterial hypotension, or from cerebral dysautoregulation; or the expression of the association of a systemic degenerative disease with another, a not infrequent occurrence well known in the pathology of the nervous system.

Cerebrovascular Disorders↗
PubMedDate not supplied

The sunflower syndrome.

Some photosensitive epileptic patients show absence attacks preceded by a "seeking of a source of light" and stereotyped movements of various kinds. The common explanation is an attempt to self-induce seizures. The case reported is of a young girl who had not shown evidence of photosensitivity for many years. Alternative interpretations of this phenomenon are discussed.

Adolescent↗