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Biomedical subjects

G K Diprose

Publications and source records attributed to G K Diprose.

4 recordsLinked to original sources

Transport dynamics of the hepato-biliary system: a mathematical model allied to Tc 99m IDA scintigraphy.

A generalised mathematical model of hepatic biliary tracer flows is formulated in terms of physiologically identifiable transport parameters. From a particular solution derived from this, the system response to intravenous administration of Tc99m IDA biliary tracer is predicted. Minimisation procedures applied to this solution combined with experimental scintigraphic observations yield estimates for the physiological parameters pertaining to a number of patient studies. Some hepatic conditions where quantitative indicators may contribute to clinical diagnosis are discussed.

Biliary Tract↗

Dinamap fails to detect hypotension in very low birthweight infants.

The accuracy of blood pressure measurements obtained from very low birthweight (less than 1500 g) neonates using the Dinamap oscillometric monitor was investigated. Comparisons using umbilical artery measurements showed that the monitor is less reliable in the lower pressure range and specifically that it tends to overestimate pressure in hypotensive infants.

Blood Pressure↗

A microcomputer monitoring and data-acquisition system for intensive care units.

A clinical monitoring system has been developed using a computer and an analogue-to-digital converter connected to standard fluid pressure and transcutaneous blood gas measurement equipment. It will collect and store information from up to four channels as trend data points, as waveform samples or as both. These monitoring and waveform recording roles have not been combined before in comparable systems. The trend data from any of the channels may be displayed on the computer screen as either a short-term (up to 3 h) or long-term (up to 99 h) graph as required. All this data may be retrieved from disk at the conclusion of monitoring to produce hard-copy for patient records. In particular the pressure waveforms have been used as the basis for subsequent research work.

Blood Pressure↗