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Biomedical subjects

G K Huang

Publications and source records attributed to G K Huang.

At least 19 recordsLinked to original sources

Use of distal arteries for microvascular reconstruction in forearm and hand surgery.

Three techniques that use distal arteries for microvascular reconstruction in forearm and hand surgery are described: (1) distal based supply from the deep branch of the radial artery, (2) proximal reversal of the radial artery, and (3) distal based supply from the ulnar artery. Nine cases are described to illustrate the use of these techniques: three vascularized bone grafts, three toe-to-hand transfers, one free cutaneous flap, one brachial artery reconstruction, and one replantation of an amputated palm. The technique offers a number of advantages: (1) it eliminates the need for vein grafts, (2) it requires only a single arterial microvascular anastomosis, (3) it minimizes microvascular size discrepancies, (4) the distal artery can be prepared in the same operative field as the rest of the reconstruction, and (5) the technique enables an undamaged artery to be brought into a zone of trauma and used as a recipient vessel. The technique has the disadvantage that it sacrifices part of the collateral circulation to the hand and it is therefore important to check the blood supply to the hand preoperatively.

Adult↗

Study on microvascular anastomosis of arteries with absorbable polyglyconate suture.

A synthetic, monofilament, slowly absorbing suture material, polyglyconate suture was tested to determine its suitability for use in microarterial anastomoses under ordinary tension and under undue tension. Microvascular repair of 34 rat femoral arteries averaging 0.63 mm in diameter using 8-0 polyglyconate suture on an atraumatic needle gave an immediate patency rate of 100% and a late patency rate of 94.1% after 1 to 24 weeks. Microanastomoses of 30 rabbit femoral arteries averaging 1.43 mm in diameter using 8-0 polyglyconate suture on an atraumatic needle gave an immediate patency rate of 100% and a late patency rate of 96.7% when a vessel segment of 3 to 7 mm was resected. Morphological studies included light microscopy and scanning electron microscopy. The results showed that polyglyconate suture retains tensile strength for an adequate period to allow vascular healing and causes a less pronounced tissue response than nonabsorbable nylon suture. Complete absorption of the suture material was followed by a complete regeneration of the vessel wall. These results demonstrated that absorbable polyglyconate suture might be suitable for microvascular anastomosis of arteries under ordinary tension and under tension to a certain degree.

Anastomosis, Surgical↗

[Experimental study of metallic bone and joint prostheses with plasma-sprayed ceramic coating].

In order to solve the loosening problem of endoprosthesis, a titanium-based alloy bone and joint prosthesis with plasma-sprayed ceramic coating was developed by the authors. By the fabrication powdered alumina or zirconium oxide were melted in an electric arc by a temperature of 10,000 K and sprayed onto the metallic prosthesis. The coating was 0.3 to 0.6 mm in thickness and had innumerable micropores. The pores were 50 to 200 microns in diameter. The metallic bone and joint prosthesis with plasma-sprayed ceramic coating exhibits characteristics of metal and ceramic, such as high mechanical strength, high resistance to corrosion and elution and good biocompatibility. According to our experimental study, the plasma-sprayed ceramic coating allows tissue ingrowth into its micropores and prevents the loosening of the prosthesis. Successful cases have been experienced through 10 years clinical application.

Aluminum Oxide↗

[Total replacement of the femur with simultaneous total hip and knee joint endoprostheses with plasma sprayed ceramic coating].

A method of prosthetic replacement using total femur incorporating its total hip and knee joints is reported. On the surface of the titanium endoprosthesis was plasma-sprayed a ceramic coating to prevent loosening of the prosthesis. It can preserve the limb and restore the function in a short period. It can be used in certain non-malignant tumours and diseases of the bone with extensively destructive lesions of the entire femur. This method was used in 3 patients with good results. The operated patients were followed-up for 32-70 (mean 54) months. Types of procedures and advantages of the operation are presented.

Adult↗

Prosthetic replacement using titanium-based alloy artificial total femur incorporating its total hip and total knee joints with plasma-sprayed ceramic coating.

The authors developed a titanium-based alloy artificial total femur incorporating its total hip and total knee joints with plasma-sprayed ceramic coating 0.3 to 0.6 mm in thickness and a myriad of micropores of 50-200 microns in diameter. On the basis of reliable data obtained in the animal experiments and physical testing, the prosthesis was applied clinically with satisfactory results. This paper reports the results of two patients with a follow-up of 42-70 months.

Adult↗

[Total femur and hip knee joint replacement with plasma-sprayed ceramic coated prosthesis].

A method of prosthetic replacement using total femur with total hip and knee joints is reported. On the surface of the titanium endoprosthesis a ceramic coating was plasma-sprayed to prevent loosening of the prosthesis. By this method the limb can be preserved and the function restored within a short period. It can be used in certain cases of non-malignant tumors and diseases of the bone with extensive destructive lesions of the entire femur. This method was used on 3 patients with good results. The patients operated on were followed up for 32-70 (mean 54) months. The procedures and advantages of the operation are presented.

Adult↗

[Results of microsurgical lymphovenous anastomoses in lymphedema--report of 110 cases].

Between 1980 and 1986, 110 patients with lymphedema of the extremities (n = 98), male and female external genitalia (n = 9), breast (n = 2), and face (n = 1) were treated microsurgically. Microsurgery for primary (n = 6) and secondary (n = 104) lymphedema at present consists of anastomosis between collective lymphatics and veins. Ninety-eight patients with lymphedema of the extremities were followed-up for 26 months. The immediate and long-term results have been very satisfactory. Excellent and good results were obtained in 76.5%. An average reduction in circumference of the affected limb of 6.2 cm and an average reduction of excess volume of 59.2 +/- 29.5% (representing 703 +/- 850 ml) were obtained. These results prove that by standardized technique the microlymphaticovenous anastomoses can produce a good therapeutic result. On the basis of our clinical experience in treating lymphedema by microlymphaticovenous anastomoses, we believe that the anastomoses should be performed early and their number should be sufficiently high. Indications, types of procedures and advantages of the operation are presented.

Adolescent↗

[Microsurgical therapy of lymphedema of the external female genitalia].

Lymphedema of female external genitalia is an uncommon disorder, for which ablative treatment procedures have been used in the past. Such an operation is most traumatic and achieved unsatisfactory results. On the basis of our experiences in treating lymphedema of the extremities by lymphaticovenous anastomosis, the author developed a microlymphaticovenous operation for treating this condition. From March 1980 to November 1984, a total of 6 patients with lymphedema of female external genitalia were operated and good results were achieved. The edema of the vulva, clitoris, mons veneris and of the lower part of the abdominal wall has been reduced, the chylorrhea disappeared and the blisters on the edematous vulva vanished. On the basis of our clinical experiences in treating lymphedema of female external genitalia by microlymphaticovenous anastomoses, we believe, that the anastomoses should be performed early and their number should be sufficiently high. The indication, types of procedures and advantages of the operation are presented.

Adolescent↗

[Microsurgical therapy of scrotum elephantiasis].

Scrotoplasty has been used in the treatment of scrotal elephantiasis but it is most traumatic and achieved unsatisfactory results. The author developed a microlymphatico-venous procedure to treat elephantiasis of the scrotum and applied it clinically with good results. The scrotal size was immediately reduced to a nearly normal value. The indication, types of procedures and advantages of the operation are presented.

Adult↗

Microlymphaticovenous anastomosis for lymphedema of external genitalia in females.

Lymphedema of the female external genitalia is seldom reported and can be psychologically distressing to the patient. On the basis of microlymphaticovenous operations for lymphedema of the extremities, a new microsurgical operation has been developed for treating lymphedema of the female external genitalia and applied clinically in six patients with good results. Edema of the female external genitalia and of the lower part of the abdominal wall has been reduced postoperatively, the chylorrhea has disappeared and the blisters on the vulva have vanished. The operative techniques and the anatomic basis of the operation are described, the six patient histories are illustrated and the correlation between number of anastomoses and quality of results are discussed herein.

Adolescent↗

Microlymphaticovenous anastomosis for lymphedema of the breast.

On the basis of microlymphaticovenous anastomosis for treating lymphedema of the extremities, the authors developed a microlymphaticovenous procedure to treat congenital lymphedema of the breast and applied it clinically in two patients. The immediate results have been fairly good. The breast and its nipple had been reduced in size and to a nearly normal level. The results are maintained after a half year of follow-up. The fundamentals and techniques of the operation are described and the two case histories are reported. The cases presented here appear to be the first successful clinical attempts to treat lymphedema of the breast by microlymphaticovenous anastomosis. The clinical character of congenital lymphedema, the indication of the microlymphaticovenous anastomosis, and the factors required for success of microlymphatic surgery are discussed.

Adult↗

Microlymphaticovenous anastomosis for treating scrotal elephantiasis.

Scrotal elephantiasis can be physically disabling and psychologically distressing to the victim. Ablative procedure has been used in its treatment and has achieved limited success. The authors developed a microlymphaticovenous procedure to treat elephantiasis of the scrotum and applied it clinically in three patients. The immediate and long-term (13-24 months) results have been very satisfactory. The scrotum size was dramatically reduced to a nearly normal level, and subjective symptoms and objective signs were improved. The operative techniques are described, the three case histories are illustrated, and the advantages of microlymphaticovenous anastomosis, the selection of patients, and the factors required for success of the surgery are discussed.

Adult↗

Influence of vessel clips on vascular patency in microarterial grafts less than 0.5 mm in external diameter.

Autogenous interpositional microarterial grafting of 140 saphenous branches of albino rat femoral arteries with an external diameter of 0.3 to 0.5 mm (mean 0.45 +/- 0.06 mm) resulted in an immediate patency rate of 100%. The patency rate observed at 72 hours was 64.3%. The late patency rate was related to blade tip pressure of the double approximator clip used in the microanastomosis. The patency rate with a clip with a blade tip pressure of 22 gm was 52.7% and that with a clip with a blade tip pressure of 2 gm was 77.3%. When arterial occlusion lasted less than 30 minutes, the late patency rate was 76.9% to 78.3%. If arterial occlusion lasted for as long as 1 hour, the late patency rate of vessels occluded by a clip with a blade tip pressure of 22 gm dropped to 27.8%. These results demonstrate that an interpositional microarterial graft as small as 0.5 mm in external diameter is clinically feasible.

Animals↗

Microvascular free transfer of iliac bone based on the deep superior branches of the superior gluteal vessels.

The findings from dissection, injection studies, corrosion specimens, and angiograms in 300 specimens of the iliogluteal region taken from 150 cadavers are reported. These findings suggest that the deep superior branches of the superior gluteal vessels may serve a nutritive pedicle in microvascular free transfer of iliac bone. Therefore, the operative technique has been developed and applied clinically with good results. The selection of different vessels as a nutritive pedicle for the free transfer of iliac bone is discussed.

Adult↗

Contracture of all the intrinsic muscles in the first intermetacarpal space.

The authors have previously described four types of intrinsic contracture in the first intermetacarpal web space. They now report a fifth group in which all the muscles in the space are involved. In this condition the thumb is flexed and adducted, and there is also radial deviation of the index finger with hyperextension of the proximal interphalangeal joint. These deformities are produced by contractures of the adductor pollicis, the flexor pollicis brevis and the first dorsal interosseous muscles. Three patients with this type of contracture are described. Operation produced an excellent result in each case, but it is essential to achieve complete correction. in a prospective study

Adolescent↗

Microlymphaticovenous anastomosis in the treatment of lower limb obstructive lymphedema: analysis of 91 cases.

Since 1980, 110 cases of lymphedema have been treated by microlymphaticovenous anastomosis. Of these 110 patients, 91 with obstructive lymphedema of lower limbs were reviewed. The immediate and long-term results have been very satisfactory. Excellent and good results were obtained in 79.1 percent. An average reduction in circumference of the affected limb of 6.4 cm and an average reduction of excess volume of 59.2 +/- 29.5 percent (representing 703 +/- 850 ml) were obtained. Subjective symptoms and objective signs were improved. Four patients (4.4 percent) showed poor results owing to severe fibrosis of neighboring tissue; no lymphatics could be located for anastomosis. As the authors gained experience with the operation over the last 3 years, they modified the operative procedure, the anastomotic technique, and the selection of collective lymphatics. The data obtained suggest that the quality of results is proportional to the number of anastomoses. In order to obtain the best results, the criteria for selection of patients and avoidance of postoperative relapse are discussed. Finally, a test for determination of the indications for microlymphatic surgery is described.

Adolescent↗

Relationship between lymphatic and venous pressure in normal and lymphedematous rabbit ears.

Studies of lymphatic and venous pressures of normal and lymphedematous rabbit ears reveal the end pressure of lymphatics to be higher than the venous pressure. Massage of the related rabbit ear increases the lymphatic pressures and can markedly raise the side and end pressures within the lymphatic wall. The venous pressures are not much affected by massaging the rabbit ear. Fluctuations in lymphatic pressure are observed with the naked eye which are associated with spontaneous and intrinsic rhythmic contraction of lymphatics. During the contraction of lymphatics the lymphatic pressure is much higher than the venous pressure. All the facts point to the conclusion that the microlymphaticovenous anastomosis for treating lymphedema has a bright future.

Animals↗