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Biomedical subjects

G K Josephson

Publications and source records attributed to G K Josephson.

7 recordsLinked to original sources

Identification of lingual glands and ducts ventrally in pigs' tongues.

Hitherto unreported tubulo-acinar mucous lingual glands were located ventrally in the free tip of the tongue, just cranial to the attachment of the frenulum linguae in 186 of 400 (47%) of pigs' tongues. The glands were bilateral in 126 (32%) of the tongues. These glands emptied by several ducts onto the ventral surface of the tongue.

Animals↗

Submandibular and disseminated zygomycosis (mucormycosis) in feeder pigs.

Submandibular and/or disseminated zygomycosis (mucormycosis) was diagnosed in 3 feeder pigs from 2 farrow-to-finish farms. Affected pigs were stunted and unthrifty. Each pig had a large unilateral submandibular granuloma replacing the mandibular lymph node on the affected side. Two pigs had disseminated lesions. One had an abscess on the serosa of the stomach; another had abscesses scattered throughout the liver and mesenteric lymph nodes. Impression smears were made of several masses and stained with blue-black ink. Examination of smears by light microscopy revealed coarse, infrequently septate, irregularly branching, mucoraceous fungi typical of a Zygomycete. Histologic examination of the submandibular masses revealed granulomas containing large numbers of mixed inflammatory cells, including giant cells. Mesenteric lymph nodes and liver abscesses had necrotic cores surrounded by fibrous capsules infiltrated by mixed inflammatory cells. Hyphae of a mucoraceous fungus were scattered throughout all masses. The 2 pigs submitted alive had marked serum hypoproteinemia, including hypoglobulinemia.

Animals↗

Porcine Haemophilus pleuropneumonia epizootic in southwestern Ontario: clinical, microbiological, pathological and some epidemiological findings.

A fibrinous necrotizing pleuropneumonia with a predominant mononuclear cell infiltrate commenced January 1978. The pneumonia, caused by Haemophilus pleuropneumoniae assumed epizootic proportions and affected mainly feeder pigs in the intensive pig rearing area of southwestern Ontario. A few abortions occurred. Winter storms, recent transportation and other potentially stressful situations were associated with herd outbreaks. Broad spectrum antibiotics were usually effective in stopping deaths.

Animals↗

Porcine neonatal coccidiosis.

Coccidia were identified in intestinal sections from 82 piglets comprising 37 consignments from 34 farms, and represented a yearly increasing incidence in the three years 1978 to 1980. Piglets were primarily from medium to large farms with intensive, continuous-farrowing, confinement-rearing programs. Piglets, usually five days to 15 days old, had yellow, fluid diarrhea, became unthrifty and sometimes died. In six piglets from two farms, a green, adherent, fibrinonecrotic membrane was seen throughout most of the jejunum and ileum. Significant gross lesions were not observed in the other 76 piglets. Moderate to severe villous atrophy of jejunum and ileum was seen histologically. Various asexual and sexual stages of coccidia were seen within parasitophorous vacuoles of villar epithelial cells. Multifocal erosions with necrosis of villar tips and occasionally more diffuse mucosal necrosis with fibrinocellular exudate were seen. Isospora suis oocysts were identified in feces from several weaners from one farm. Amprolium and decoquinate mixed in the sow ration at 1 kg/tonne for three weeks prior to and postfarrowing was moderately successful in stopping outbreaks of neonatal diarrhea associated with coccidiosis.

Animals↗

Tuberculosis in farmed rheas (Rhea americana).

Avian tuberculosis was diagnosed in two mature rheas on different ratite farms over a 2-year period. Both birds had died after progressively losing body condition. Caseonecrotic granulomas were scattered throughout the liver and spleen in both birds. Similar granulomas were in the lung of one bird and bilaterally in the subcutis cranial to the shoulder in the other bird. Smears of several granulomas from both rheas revealed large numbers of acid-fast bacilli. Histologically, the granulomas had caseonecrotic, non-mineralized centers surrounded by giant cells. Large numbers of acid-fast bacilli were seen free in the necrotic material and within inflammatory cells. Amyloidosis of the liver and spleen occurred in one rhea. Mycobacterium avium complex was isolated at a reference laboratory from hepatic granulomas submitted from one rhea.

Animal Husbandry↗