[Antiblastic effects of polycation polyhexamethyleneguanidine, a representative of a new class of antitumor drugs].
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Biomedical subjects
Publications and source records attributed to G K Zakenfel'd.
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A new method was elaborated for the combined chemoimmunotherapy of cancer and hematosarcoma of the stomach by means of intratumoral submucous injection via a fiberoptic endoscope of 5-fluorouracil (or cyclophosphane) followed by general ftorafur chemotherapy (or vincristine, cyclophosphane, 5-fluorouracil) followed by general ftorafur chemotherapy (or vincristine, cyclophosphane, 5-fluorouracil), or by intratumoral submucous injection of zymosane at termination of the chemotherapy course. The material comprising 96 patients, treated by the new method and 52 control patients after general chemotherapy has proved a greater efficacy of the method of combined chemoimmunotherapy, especially in infiltrative-exophytic and perigastric recurrences of cancer of the stomach as well as in radically operated subjects.
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