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Biomedical subjects

G Kalla

Publications and source records attributed to G Kalla.

14 recordsLinked to original sources
PubMed2000

Histoid, a clinical variant of multibacillary leprosy: report from so-called nonendemic areas.

This is a hospital-based study of 25 biopsy-proven cases of histoid leprosy in the arid, northwest Rajasthan region of India. Over an 11-year span, a total of 893 new cases of leprosy were diagnosed at our institution. These 25 histoid cases thus make up 2.8% of our new patients. Various clinical and laboratory observations are summarized and compared to other published series.

Adolescent↗
PubMed1978

Leprosy in Jodhpur (Rajasthan). Clinical and epidemiological study.

A clinical and epidemiological study of leprosy revealed 232 cases in Jodhpur (Rajasthan); a non-endemic area. Males were three times more affected than females. Lepromatous leprosy was the most common type (70.70%). Maximum number of cases were observed in the age group 20-49 years. The probable causes for an increase in incidence are discussed.

Adolescent↗
PubMedDate not supplied

Juvenile generalized pustular psoriasis.

A 4-year-old boy had a generalized, confluent, pustular eruption on an erythematous base of three weeks' duration. He was febrile and toxic. He had had a similar problem at age 5 months that lasted for about four weeks. The child was initially treated conservatively, but later developed erythroderma and became increasingly toxic. This necessitated administration of oral methotrexate 2.5 mg/day at weekly intervals. After two pulses there was marked improvement in his psoriasis.

Age of Onset↗
PubMedDate not supplied

Dexamethasone-cyclophosphamide pulse therapy in systemic lupus erythematosus.

BACKGROUND AND AIMS: Therapy systemic lupus erythematosus (SLE) has been generally discouraging. Methyl-prednisolone pulse therapy has been used for various connective tissue disorders. We used intravenous dexamethasone cyclophosphamide pulse therapy to treat SLE. METHODS: Fourteen patients (10 females and 4 males) between the age of 15-48 years with definite or classical clinical criteria laid by American Rheumatism Association criteria were treated by Dexamethasone-Cyclophosphamide pulse (DCP) therapy at our center. RESULTS: It was possible to induce a complete clinical remission with DCP therapy in most of the patients thereby offering them life free from disease and drugs. The side effects commonly observed with conventional daily dose regimen of corticosteroids were not present or were mild. CONCLUSIONS: Almost all patients had good response after 3-4 pulses to allow them a normal life style. Fever, malar rash and oral ulceration responded early but photosensitivity, discoid rash, alopecia and joint pains took some more time.

Adolescent↗
PubMedDate not supplied

A clinico-epidemiological study of leprosy in arid north-west Rajasthan, Jodhpur.

A detailed clinical, bacteriological and histopathological study of 1373 patients of leprosy who sought medical advice at the Department of Skin, STD and Leprosy of Dr. Sampurnanand Medical College, Jodhpur, during 1975-1993 is reported. The disease was observed in 1.54 patients per 1000 cases attending in the skin department out-patients. More than 50% of them had polar type of lepromatous leprosy. The disease was found 2.42 times more often in males than in females and was found mainly in the age group 11-70 years. Family history of leprosy was obtained in 130 (9.5%) of the cases. Lepra reactions were seen in 151 (11%) cases, of which 30 had type 1 reaction (19.2%) and 121 type 2 reaction (80.1%). The majority of leprosy cases (966 or 70.4%) were from Jodhpur district, followed by 109 (7.9%) from Nagaur district and then from, Barmer, Jaisalmer and Jalore etc. All cases of leprosy responded well to the WHO regimens of multidrug therapy. The reactional cases were satisfactorily managed with higher doses of clofazimine along with oral prednisolone.

Adolescent↗