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Biomedical subjects

G Kammerer

Publications and source records attributed to G Kammerer.

5 recordsLinked to original sources

[Studies on the allergenic potential of palladium alloys].

Epicutaneous tests with test solutions of the European standard series and palladium chloride (1%) were performed in 486 patients of the University Hospital for Dermatology in Aachen. 17.9% of the patients exhibited Ni, 8.6% Co, 7.4% Pd and 4.1% Cr allergy. In 18 of 36 patients with a positive patch test reaction a further epicutaneous and epimucosal testing with metallic plates of pure palladium and a palladium alloy was performed. In 34 cases a positive skin reaction to palladium chloride was combined with a positive skin reaction to nickel sulphate. Only in one case was it possible to demonstrate an allergic reaction to a palladium metallic plate, which was tested additionally in artificial saliva. The results show that a dental alloy envisaged for use should be tested in an epicutaneous test, if the patient shows a positive reaction to the metallic salt solution. In case of positive patch tests to nickel sulphate, dental palladium alloys should not be used as an alternative unless sensitivity to palladium has been tested.

Dental Alloys↗

Influence of systemic ascorbic acid treatment on metabolite levels after regeneration of the corneal epithelium following mild alkali burns.

Between 6 and 16 days after mild alkali burns of rabbit eyes, the aqueous humor and corneal stroma ascorbic acid levels were decreased in the untreated animals. Systemic treatment with ascorbate 0.5 g/kg body weight injected daily subcutaneously) raised the reduced ascorbic acid levels to twice the normal values in the aqueous humor, but those of the corneal stroma increased only slightly and remained far below the normal levels. The systemic ascorbate treatment did not improve the healing rate of the corneal epithelium, but increased adenosine triphosphate and diphosphate levels as well as the ATP/ADP ratio of the glutathione was shifted to a more reduced state.

Alkalies↗