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Biomedical subjects

G Karayalcin

Publications and source records attributed to G Karayalcin.

At least 37 records · Page 2Linked to original sources
PubMed1981

Serum alpha-hydroxybutyrate dehydrogenase levels in children with sickle cell disease.

Serum alpha-hydroxybutyrate dehydrogenase (alpha-HBDH) levels were determined in 28 children with homozygous sickle cell disease (SCD) during the steady state, crisis, and postcrisis periods. Serum alpha-HBDH levels were also studied in 20 patients with infection. In patients during the steady state, serum alpha-HBDH levels were significantly above control values. During the vaso-occlusive crisis there was a significant further increase in the alpha-HBDH levels. In patients with infection, however, there was no significant increase in serum alpha-HBDH levels. These findings clearly indicate that the level of serum alpha-HBDH in patients with SCD permits differentiation between vaso-occlusive crises, infection, and spurious symptoms.

Adolescent↗
PubMed1979

Cholelithiasis in children with sickle cell disease.

A group of 47 children with homozygous sickle cell disease ranging in age from 2 to 18 years was studied for the prevalence of gallstones. All of these patients had oral cholecystogram and cholecystosonogram. Eight of the 47 patients (17%) had gallstones both on oral cholecystography and on cholecystosonography. These eight patients had a history of recurrent abdominal pain usually localized to the right upper quadrant. All were admitted on several occasions for sickle cell abdominal crises and four of these were admitted for acute hepatic crisis. These patients have undergone elective cholecystectomy and gallstones were found in every patient. The patients have been followed up from seven to 17 months after cholecystectomy and none have had abdominal symptoms or required hospitalization for abdominal crises.

Adolescent↗
PubMed1979

Sickle cell anemia in the neonatal period.

Although sickle cell anemia rarely presents with clinical manifestations in the newborn period, it should be considered a possible cause of unexplained early jaundice in black newborn infants. If sickle cell disease is suspected, sickle cell preparation and hemoglobin electrophoresis of the infant and of both parents should be carried out.

Anemia, Sickle Cell↗
PubMed1979

Gray scale ultrasound: evaluation of iliopsoas hematomas in hemophiliacs.

Because of its insidious nature, intramuscular bleeding, in contrast to hemarthrosis, is missed or belatedly recognized in hemophiliacs. Sixteen patients with suspected iliopsoas bleeding were studied by gray scale ultrasonography. In 12 patients it was possible to confirm the diagnosis of iliopsoas hematoma because of enlargement and rounding of the psoas muscle.

Adolescent↗
PubMed1979

Experience of children with sickle cell anemia in a regular summer camp.

The Sickle Cell Program of the Queens Hospital Center Affiliation of the Long Island Jewish-Hillside Medical Center arranged for a group of children from the hospital Sickle Cell Clinic to spend one week during the summer of 1978 in a sleepaway camp for healthy children. This paper analyzës the results of the experience.

Anemia, Sickle Cell↗
PubMed1979

Zinc deficiency in children with sickle cell disease.

Zinc status was studied in 47 children with homozygous sickle cell disease (SCD). Decreased hair and plasma zinc was demonstrated in these children and hyperzincuria was found in the older patients. This study indicates that zinc deficiency in patients with SCD is probably due to hyperzincuria.

Adolescent↗
PubMed1978

Partial exchange transfusion in sickle cell anemia. Use in children with serious complications.

Seventeen children with sickle cell anemia received 40 partial exchange transfusions for serious complications of sickle cell anemia, and preoperatively to reduce the risk of anesthesia. Each patient received two partial exchange transfusions at 24-hour intervals and all patients tolerated the exchange transfusions well. The mean hematocrit level rose from 22.9% before the exchange transfusion to 40.6% at the end of the second exchange. The mean sickle hemoglobin level decreased from 93.8% before the exchange to 28.0% after the second exchange. Patients with acute lung syndrome had remarkable improvement in clinical symptoms and PaO2 levels, and those with acute liver crisis had substantial reduction in serum bilirubin levels. All the other patients showed marked clinical improvement following the exchange transfusions.

Anemia, Sickle Cell↗
PubMed1977

Monocytosis in congenital syphilis.

We evaluated hematological findings, with special reference to the monocyte count, in ten infants with congenital syphilis. One patient had a monocytic leukemoid reaction and eight had absolute monocyte counts considerably higher than normal control infants. Monocytes appear to be an essential participant in the cellular reaction to treponema pallidum. To our knowledge, this is the first report of a monocytic leukemoid reaction in congenital syphilis.

Female↗
PubMed1976

Staging laparotomy and splenectomy: treatment and complications of Hodgkin's disease in children.

Twenty-five cases of hodgkin's Disease (15 males and 10 females) aged 5 to 17 years were studied from April 1970 to July 1976 (75 month period). Histology revealed that 2 had lymphocytic predominance, 12 had nodular sclerosis, and 11 had mixed cellularity. Pathologic staging revealed that 3 were IA, 1 IB, 5 IIA, 4IIB, 6IIIA, and 6 IIIB. Laparotomy altered the staging in 12 patients (9 were staging up and 3 down). All but 2 patients received extended field radiation, and 5 had recurrence of disease and were treated with combination chemotherapy. Twenty-three are alive without evidence of disease (21-75 months), and the 2 deaths were not due to Hodgkin's Disease but to hemobilia (postliver biopsy) and penumococcal septicemia, purpura fulminans, and disseminated intravascular coagulation (14 months postsplenectomy). Other complications included 2 patients with intestinal obstruction, 1 with postoperative subphrenic abscess, and 1 with streptococcal septicemia and polyarthritis. Nineteen patients received continuous penicillin prophylaxis postoperatively and the 2 with serious infections were amongst the 6 who had not received penicillin or whose penicillin had been discontinued at the time of infection. It is concluded that laparotomy and splenectomy in children is essential for accurate staging but carries significant risk, and continuous penicillin prophylaxis is recommended.

Adolescent↗