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Biomedical subjects

G Karlin

Publications and source records attributed to G Karlin.

6 recordsLinked to original sources

Percutaneous pyeloplasty (endopyelotomy) for congenital ureteropelvic junction obstruction.

Endopyelotomy was performed in 30 patients with congenital primary ureteropelvic junction obstruction; 4 patients had high insertion of the ureter and 8 patients had caliceal stones. Clinical and radiologic success was achieved in 25 patients. There were five failures, all of whom subsequently had successful open pyeloplasty. The theoretical and experimental foundations of the procedure and fine points of the operative technique are presented. Endopyelotomy appears to be valuable for primary ureteropelvic junction obstruction just as it is for secondary obstruction.

Adolescent↗

Endopyelotomy.

Explore the source record for details and available documents.

Humans↗

Benefits of an ultrasound-guided ESWL unit.

Ultrasound is ideally suited for imaging of renal calculi for extracorporeal shock wave lithotripsy. Ultrasound can localize radiolucent stones, monitor fragmentation in real time, and differentiate the stone from a stent. Its use significantly reduces the radiation exposure to patient and operator, which is particularly desirable in the pediatric patient. Furthermore, sonography-guided lithotripsy can reveal any incidental finding in the affected kidney that may require further evaluation and familiarizes the operator with this increasingly useful imaging method. The ultrasound-guided Sonolith 3000 with its enlarged ellipsoid aperture has a decreased energy focus size and voltage, permitting fragmentation with reduced anesthesia requirements. The initial extracorporeal shockwave lithotripsy (ESWL) machine, the Dornier H3, uses fluoroscopy for stone localization and treatment monitoring. Although this imaging method has the benefit of being familiar to urologists, it has some drawbacks, such as difficulty in imaging some types of stones and the radiation exposure of the operator and the patient. We have been using the Technomed Sonolith 3000 ESWL machine, which uses ultrasound to localize stones. During this experience, we have found a number of obvious and not so obvious benefits. For example essentially all calculi are echogenic, irrespective of their radiologic density. Moreover, with ultrasound, fragmentation can be monitored by real-time imaging, making determination of the treatment end point easier, and the stone and stent can be differentiated clearly. Ultrasound also can reveal other pathology and eliminates radiation exposure. Moreover, an ultrasound-guided ESWL unit familiarizes the operator with ultrasound techniques, and the same machine can be used for biliary lithotripsy. All of these features make ultrasound imaging for ESWL desirable.

Evaluation Studies as Topic↗

Persistent cloaca and phallic urethra.

During the last 8 years 54 children with a persistent cloaca have been treated by one of us (A. P.). The most common associated anomalies involved the urinary tract, with renal agenesis, renal dysplasia, vesicoureteral reflux and megaureter encountered most frequently. Four patients demonstrated the rare entity of an opening at the tip of a pseudophallus and 2 also had an accessory urethra in association with the cloacal malformation. These children exhibited some form of masculinization of the external genitalia with the accessory urethra or cloacal channel assuming a phallic position in an enlarged clitoris. No adrenal, metabolic or chromosomal abnormalities were detected and virilization was limited to the genitalia. These cases illustrate the greater predilection of these patients to more complex congenital malformations than patients with an isolated cloaca. The posterior sagittal approach has been used effectively for repair of these congenital malformations.

Abnormalities, Multiple↗

Complications of endopyelotomy: analysis in series of 64 patients.

We review the complications and failures in our first 64 patients who underwent endopyelotomy. There were 2 intraoperative complications (3.1 per cent) necessitating an open operation. Postoperative complications included leakage around the stent or irritative bladder symptoms, which were treated by repositioning the stent, and 2 instances of ureterovesical stenosis, which have led us to stent the entire ureter in recent cases. There were 7 failures, 4 in patients who in retrospect were not suitable candidates for the percutaneous operation (long stenotic segment and redundant renal pelvis) and 3 for which there was no obvious cause. All failures were apparent soon after removal of the stent that was inserted at the end of the procedure.

Adolescent↗

Percutaneous ureterostomy.

Percutaneous ureterostomy was performed bilaterally in 1 patient and unilaterally in another when easier methods of total diversion failed. This advanced endourological technique is most applicable in a thin patient with tortuous ureters.

Aged↗