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Biomedical subjects

G Karussos

Publications and source records attributed to G Karussos.

5 recordsLinked to original sources

An analysis of cerebrospinal fluid shunt infections in adults. A clinical experience of twelve years.

The authors analyze a group of 451 shunt operations where 317 patients had hydrocephalus and 23 cases were reported positive after cerebrospinal fluid (CSF) cultures. Staphylococcus was the most frequent bacterial organism found (57%). This retrospective study of 23 patients in whom infection developed following placement of an extrathecal shunt, although not a complete biometric evaluation, shows an incidence of infection of 5%. The authors also indicate the limitations in antibiotic treatment when three significant aspects of therapy are not considered fully: 1. sensitivity of the identified organism, 2. CSF levels of the drug that can be attained, and 3. the pharmacokinetic action of the drug in the CSF.

Adolescent↗

CSF shunt infection management in adult age.

This retrospective study of nine patients in whom infection developed following operation for placement of an extrathecal drainage shunt, although it is not a complete biometric evaluation, shows an incidence of infection (10.5%) that corresponds with averages reported from other centers [7, 15--17]. Furthermore, it points out the limitations of antibiotic treatment when three significant aspects of therapy are not considered fully: 1) sensitivity of the identified organism, 2) CSF level of drug that can be achieved, and 3) pharmacokinetic action of drug in CSF.

Adult↗

Postoperative scars and recurrent disk herniation: clinical, neuroradiological, and surgical findings.

Authors present 36 patients with recurrent sciatica or low-back pain after lumbar disk operation. All patients were submitted to clinical and instrumental devices. CT-scan was performed in 36 patients, 12 underwent myelography and 4 EMG. Authors verified reliability of clinical and instrumental devices on the basis of surgical results. We believe that myelo-CT is actually the first choice investigation in the neuroradiological ones. In the near future MRI will take its place in investigating spinal pathology.

Adult↗

[Post-traumatic hydrocephalus].

Post-traumatic hydrocephalus is a complication of cranio-cerebral injuries and can manifest itself through different clinical syndromes. These include obtunding, a tetrad composed of psychomotory delay, memory loss, motility disturbances and sphincter incompetence, and unusual symptoms which comprehend emotional disturbances. Intracranial pressure monitoring, lombo-ventricular infusion test, in addition to neuroradiologic exams, are necessary in order to decide wether or not to derivate a post-traumatic hydrocephalus; neuropsychologic tests complete these investigational methods. The post-traumatic hydrocephalus bearer patient's recovery is always problematic when an important parenchimal damage exists. When a NPH (normal pressure hydrocephalus) is found the shunting operation is always indicated. However it is difficult to take a decision when the patient has a normal liquoral pressure but is too wounded to show a NPH or when he has an atypical clinical feature.

Brain Injuries↗