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G Kenan

Publications and source records attributed to G Kenan.

3 recordsLinked to original sources
PubMed2005

Electrical impedance scanning for melanoma diagnosis: a validation study.

BACKGROUND: A multicenter study was conducted to test the ability of electrical impedance scanning to differentiate between benign and malignant skin lesions. The performance of a dual electrical impedance scanning/image analysis device was also assessed. METHODS: Electrical impedance scanning measurements of 449 preoperative lesions found on 382 patients and including 53 melanomas from the trunk and extremities were performed. Results were correlated with histopathologic findings. In addition, ABCD parameters for the lesions were automatically calculated by the system. RESULTS: Electrical impedance scanning detected melanomas of the trunk and extremities with 91 percent sensitivity and 64 percent specificity. Moreover, sensitivity of electrical impedance scanning was increased to 100 percent for in situ and thin melanomas of smaller size (n = 27). Visual examination identified as malignant only 67 percent of these early tumors (p = 0.002). Clinical examination detected 96 percent of the larger or thicker melanomas (n = 26), whereas electrical impedance scanning detected only 81 percent of them. Combined electrical impedance scanning and image analysis detected 100 percent of the melanomas, independent of their thickness, and with no significant decrease of specificity. Because of electrical differences between the head/neck and the rest of the body, the assessed electrical impedance scanning parameters were not adequate for the diagnosis of melanomas from the head and neck. CONCLUSIONS: A validation study proved the value of electrical impedance scanning as a noninvasive technique for detection of melanoma lesions of the trunk and extremities, specifically, of in situ and thin type. In addition, image analysis was shown to be a valuable, complementary procedure. New parameters should be designed to optimize the performance of electrical impedance scanning for melanomas of the head and neck.

Adult↗
PubMedDate not supplied

Trends in patrilineal parallel first cousin marriages among Israeli Arabs: 1949-1995.

BACKGROUND: Consanguineous marriages are one of the means by which lineal clans maintain themselves. As it happens, there is a biological price to be paid for consanguinity, which is strongly felt particularly in populations where mortality is low. PRIMARY OBJECTIVE: This study seeks to estimate trends in consanguinity among the Muslim and Druze populations of Israel during the period 1949-1995. METHODS: The Israel Population Register is a continuously updated disk record of all current and former citizens. A copy of this record, as of 31 October 1995, was used to construct a file of all Muslim and Druze marriages that had taken place between 1949 and 1995. The marriage records include the given names of the paternal grandfathers of husband and wife. Couples whose grandfathers have the same name may be parallel patrilineal first cousins. A probability algorithm was constructed which provides an estimate, for each name, of how many of these couples are in fact first cousins. The estimates are then summed over all names to provide a population estimate. This procedure was carried out separately by religion, marriage period and region. RESULTS AND CONCLUSIONS: Statistically significant declines in consanguinity were found for the Muslim populations of northern Israel, since 1965, and for Jerusalem, since 1949. For the Bedouin of the Negev only a temporary decline was found, for a short time after the reopening of the borders with Gaza, Sinai and the West Bank in 1967. Significant declines in consanguinity were also found for the Druze of northern Israel, after 1982. It is considered, though not demonstrated, that the secular declines are associated with increasing levels of education and urbanization known to have occurred in these populations.

Algorithms↗