PubMed Health⌕ Search

Biomedical subjects

G Kerkovits

Publications and source records attributed to G Kerkovits.

18 recordsLinked to original sources
PubMed2002

Cardiac digital image loops and multimedia reports over the internet using DICOM.

The authors define an open, scaleable telemedicine architecture to reduce the time of reports delivery and consultation; increasing their simplicity via introducing common image presentation, storage and telecommunication formats and methods for telecardiology. They've developed a software application to implement it introducing the most appropriate digital imaging methods and formats using the latest available technology.

Cardiac Catheterization↗
PubMed2001

[Primary percutaneous coronary angioplasty in acute myocardial infarction. Measures of quality control for the work of the hemodynamics laboratory].

The results of primary percutane coronary angioplasty in acute myocardial infarction were studied and compared to international standards. We tried to develop new quality indicators for objective comparison. Seventy nine patients with acute myocardial infarction were included in the study, 47 of them from the pre-stent, and 32 from the stent era. The primary success rate was 91.5 and 81 per cent, respectively. Six months event free period was achieved in 74 and in 69 per cent. The mortality reduced from 10.6 per cent to 3.1 per cent. No emergency by-pass operation was needed in the stent group.

Adult↗
PubMed1997

[Use of coronary vessel prosthesis. Complex coronary angioplasty under general anesthesia].

In 1995 we attempted to treat with PTCA 437 ischemic patients. We stended 29 patients (6.6%) with 34 stents. Emergency stenting was done in 5, semi-elective stenting in 6, and elective stents were applied in 18 patients with restenosis. We have achieved good angiological results without occurrence of myocardial infarction, with no emergency open heart surgery or death. No intracoronary thrombosis was observed during one-month follow-up with combined aspirin and ticlopidin treatment. Hemodynamical and angiological high-risk patients were treated under general anesthesia with assisted respiration. No complications were observed during the procedures. In cases of in-stent restenosis (17%) we redilated the coronary artery. This technique proved to be promising and is routinely applied world-wide to optimise immediate and long-term results of PTCA. The realisation of such interventional cardiological centers with appropriate financial background is an absolute requirement for spreading this technique in Hungary.

Aged↗
PubMed1994

Hungarian Isradipine Study (HIS): long-term (3-year) effects on blood pressure and plasma lipids.

These are the preliminary data of an open multicenter trial of antihypertensive treatment with isradipine as monotherapy (dose, 4.55 +/- 0.56 mg twice daily; n = 11) or isradipine (7.5 +/- 0.63 mg twice daily) in combination with bopindolol (1.16 +/- 0.12 mg once daily; n = 30) administered for 3 years to patients with essential hypertension (WHO classification I or II). Blood pressure was significantly decreased in both treatment groups and there was no indication of resistance to therapy. Plasma levels of total cholesterol and triglycerides were decreased by the end of the second year of treatment, and there was a tendency toward increase in plasma levels of high-density lipoprotein cholesterol (HDL2 or HDL3). The atherogenic index (ratio between total cholesterol and HDL2 plus HDL3) was also decreased. Blood glucose levels remained unchanged in both normoglycemic patients and those with non-insulin-dependent diabetes mellitus (NIDDM) during 3 years of therapy. It is concluded that isradipine is safe and effective when administered long-term in the treatment of hypertensive patients with either hyperlipidemia or NIDDM.

Adolescent↗
PubMed1993

Comparative examination of Adalat and Cordaflex in anti-ischaemic therapy.

The efficacy of Cordaflex (EGIS) and Adalat (Bayer), both containing 10 mg nifedipine, has been examined in ischaemic cardiopathic patients. The fifteen ischaemic cardiopathic patients were treated with identical doses of Cordaflex and Adalat, simultaneously with unchanged nitrate and beta-blocker therapy. The patients received 30-80-mg identical nifedipine doses daily for 1 week each. In 13 patients change was observed neither in the weekly nitroglycerin consumption nor in the time or intensity of silent and active ischaemic periods registered with 24-hour ECG monitoring. Significant change was observed in one patient during Cordaflex administration, in another patient during Adalat therapy. However, these changes were attributed either to the progression of, or to the spontaneous improvement in the primary disease. Considering the effect influencing blood pressure and heart rate, and one side-effect, there was no difference between the two products. The anti-ischaemic effect of Cordaflex and Adalat was found to be identical.

Adrenergic beta-Antagonists↗
PubMed1990

Antihypertensive effect of bopindolol: a multi-centre study.

The objective of the study was to investigate the efficacy of different dose levels of bopindolol monotherapy in hypertension. This potent nonselective beta-adrenergic receptor blocker has intrinsic sympathomimetic activity and long duration of action. Forty-four patients with essential hypertension of mild (n = 40) or moderate (n = 4) severity (90 less than DBP less than or equal to 115 mmHg at the end of the placebo period) entered and completed the single-blind, placebo-controlled trial. The study lasted 14 weeks: 2 weeks on placebo, and 12 weeks on active treatment during which the initial dose of bopindolol, 1 mg daily, was augmented up to 1.5 mg, then to 2 mg at four-week intervals until BP normalized or a maximum dose of 2 mg/day bopindolol was reached. The bopindolol was administered once a day in the morning. Patients were seen every other week in the morning before drug taking, when BP and heart rate, supine and standing, a twelve lead ECG and side-effects were recorded. Compared with placebo, supine BP was significantly reduced by bopindolol: from 169 +/- 2/103 +/- 1 mmHg to 148 +/- 3/92 +/- 1, 144 +/- 3/90 +/- 1 and 136 +/- 2/85 +/- 0.6 mmHg at the end of 4, 8 and 12 weeks of treatments, respectively (P less than 0.01 for each). BP changes during standing were similar. Bopindolol lowered the supine heart rate from 84 +/- 2 to 75 +/- 1, 74 +/- 1, 72 +/- 1 beats/min (P less than 0.01).(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗
PubMed1990

Clinical examination of heparin-Ca in myocardial infarction patients.

The clinical effect of subcutaneous heparin-Ca of delayed action (Heparin Calcium inj. 25,000 IU/ml, Chemical Works of Gedeon Richter) has been examined in 26 acute and 6 imminent myocardial infarction patients. The therapy was started with 10,000 IU intravenous heparin dose. Subsequently the native blood coagulation time (Lee-White) was continuously maintained on the therapeutic level with subcutaneous injections administered every 12 hours. Except for superficial haemorrhages other side-effects were not observed in any of the cases. Anticoagulant therapy was continued with Syncumar tablet from days 4-5 of acute myocardial infarction.

Adult↗
PubMed1989

Captopril (Tensiomin) in the treatment of chronic heart failure of ischaemic heart disease patients.

The authors used Captopril (Tensiomin, Egis Pharmaceuticals, Budapest) therapy in seven patients suffering from chronic heart failure of ischaemic etiology. As controls, seven patients with dilated cardiomyopathy were involved in the study. All 14 patients received digitalis, diuretic, and isosorbide dinitrate therapy but their condition aggrevated in spite of the therapy. The above-mentioned therapy was completed with daily 3 x 12.5-mg or 3 x 25-mg oral Captopril doses. Significant improvement proved by chest X-ray, echocardiography, and clinical data was observed in four of the ischaemic heart disease patients and three of the dilated cardiomyopathic patients. In other two patients each the improvement was temporary, after 6 weeks of therapy deterioration of the disease was observed. Notable change was not observed in response to Captopril in one ischaemic and two primary cardiomyopathic patients. Tensiomin may be considered as one of the drugs of primary importance in the treatment of chronic congestive heart failure.

Adult↗
PubMed1975

Baropacing of the carotid sinus nerve for treatment of "Intractable" hypertension.

The authors applied with success the electrical stimulation of the carotid sinus nerve in the case of a hypertension of long duration which was refractory to antihypertensive drugs. For the stimulation of the carotid sinus nerve a Medtronic "Barostat" device was implanted. Since the implantation- or rather since its usage- the blood pressure of the patient decreased to a great extent, and her complaints disappeared. According to the haemodynamical investigations on the effect of the stimulation of the carotid sinus nerve, besides the diminution of the blood pressure there could be observed a decrease of the cardiac index, the total peripheral vascular resistance and the velocity of the blood circulation.

Adult↗