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Biomedical subjects

G Kirov

Publications and source records attributed to G Kirov.

5 recordsLinked to original sources
PubMed1991

[Retroperitoneal sarcomas].

Sixteen years experience (1974-1989) is recorded with the treatment of 18 patients with retroperitoneal sarcoma. The tumor was palpable in all. Four syndromes could be differentiated in these patients: gastrointestinal, renal, vascular and neurologic. All modern methods of diagnosis were applied: ultrasonography in 12 patients, computer tomography--13, angiography--3, X-ray examination of the gastrointestinal tract--7, gamma-renography--5, urography--2. Radical operative intervention is considered treatment of choice, followed by radio- or hemotherapy. Radical extirpation of the tumor was performed in 10 patients (55.5 per cent). Extended operative interventions with resection of adjacent organs were performed in 4 patients (22.2 per cent). After histologic verification 10 patients (55.5 per cent) were subjected to chemotherapy and 7 to radiotherapy. Postoperative case fatality rate was 17 per cent (3 patients died). Four patients 22.2 per cent) had relapse of the tumor between the first and the third year.

Adolescent↗
PubMed1990

[Retroperitoneal and mesenteric cysts].

Experience is recorded with the diagnosis and successful surgical treatment of 5 patients with retroperitoneal and mesenterial cysts. According to available data in the literature, one patients with retroperitoneal or mesenteric cyst falls among an average of 34,000-105,000 in-lying patients. Basic symptom on physical examination was a palpable tumor mass in the abdomen. In recent years correct preoperative diagnosis of these diseases has been established in 85-95 per cent of the cases with the help of echography and computer tomography. The surgical approach was determined from the possibility for total or partial removal of the cyst, which was sometimes accompanied by partial or total removal of abdominal organs involved in the pathologic process.

Adult↗
PubMed1987

[In vitro research on the interaction of natural zeolites with diploid cells from the human embryonic lung].

A study of the biological effect of the natural zeolites, clinoptilolite, mordenite and erionite on monostratum cellular culture of human embryonic lung is performed. The number of pyknotic cells, morphological changes in the cells, and monostratum, mitotic activity and changes in the cellular culture are reported during a continuous experiment. As positive control is used standard quartz dust DQ-12 and for negative dust of TiO2. It is already established that the dust particles of natural zeolites with dimensions under 5 micron display biological aggressiveness. With most strongly expressed effect is the clinoptilolite dust, which related to identical active surface, is comparable to that of quartz DQ-12. The mordenite is with moderate cytotoxic effect, proportional to the time and concentration, while erionite is with slight and very delayed effect. There are differences concerning the effect on the miotic activity of the cells. The biologic aggressiveness of the zeolites is discussed in relation to their strong active surface, their ionometabolic properties and their capacity to generate hydrogen at moistering.

Aluminum Silicates↗