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Biomedical subjects

G Korten

Publications and source records attributed to G Korten.

15 recordsLinked to original sources
PubMed1990

[Measuring the thickness of the peritoneum as a dialysis membrane using various osmolar concentrations of dialysis fluid].

Thickness measurements solutions on the rat peritoneum using peritoneum using peritoneal dialysis solutions of various osmolalities show a marked reduction of the distances between capillaries and peritoneal surface with increasing osmolality. This may caused by a dehydration of the peritoneum and support the so-called canaliculus theory. If the dehydration of the peritoneum may outlast temporal the dialysis cycle with higher osmolar solution, it could be an explanation for the efficacy of following low-molecular solutions.

Animals↗
PubMed1988

[Nutritional problems in patients treated with chronic dialysis].

A food with a protein content of 100-110 g a day determined for dialysis patients was analysed for total weight, water content, protein content, energy content, potassium content and phosphate content during 13 days. During this time 152 individual nutritive substances were offered, which were classified into the group of meats and sausages, egg, milk, milk-products, bakery-goods, potatoes and vegetables. It is to be stated that highly significant positive correlations between the weight of the daily taken food and its content of water, protein, energy, potassium and phosphate are existing, whereby a quantity of 1 kg a day is preferred. For the daily protein intake of 1.0-1.5 g/body weight-1.-d1 required in patients with chronic dialysis treatment, dependent upon dialysis technique and nutritional state, this simultaneously means a dependence of the total quantity of food to be taken in upon body weight, which again has effects on the dialysis regime and the ultrafiltration, since a more or less intensive intake of water, potassium and phosphate is connected with this. The removal of catabolic conditions is a scarcely soluble problem above all in dialysis patients with high optimum weight, by which the often existing inappetence inhibits the necessary increased food intake. The is furthermore rendered difficult in the peritoneal dialysis with peritonitis, since the ultrafiltration is reduced by the inflammation so that the water taken in with food cannot be excreted in a necessary degree.(ABSTRACT TRUNCATED AT 250 WORDS)

Dietary Proteins↗
PubMed1988

[Scanning electron microscopy study of the peritoneum as a dialysis membrane--a morphological study on the etiology of sclerosing peritonitis].

Scanning electron microscopy investigations of the surface of rat peritoneum were performed after application of isotonic saline solution and peritoneal dialysis solutions with osmolalities of 375, 528, and 680 mosmol x kg-1 and intraabdominal stay periods of 15, 30, and 45 minutes. Severe morphological changes of the peritoneal surface were shown as clotting and atrophy of microvilli, detachment of surface cells from the basement layer, destruction of the basal lamina and appearance of rough-fibrous submembranous connective tissue, which was observed even after application of isotonic saline solution into the abdominal cavity. In conclusion, sclerosing peritonitis is caused by a fruitless inflammation reaction of the organism against the unphysiological function of the peritoneum as dialysis membrane forced upon peritoneal dialysis.

Animals↗
PubMed1987

[Determination of caries activity levels in children aged 4-6 years by the modified Snyder test].

Modified Snyder Test, which is a good instrument in motivating the patient and determining the effectiveness of preventive programs, is used commonly in Public Health Research programs for measuring the the caries activity levels. In our study, by using modified Snyder Test instead of Snyder Test, which is more preferable because of its' simplicity in application, we determined the caries activity levels of the children, aged between 4-6 years, which remained as an unexamined group in our population up to date. In our study, consisting of fifty children, caries rate was found to be 36% depending on WHO's criteria, while caries percentile for each tooth was 5.8% and df index was 1.18. According to the modified Snyder Test results, 46% of the children had positive results at the end of the 48 hours, which indicates a mild caries activity degree. This result is also in accordance with the caries of the group.

Child↗
PubMed1985

[Optimization of peritoneal dialysis using diffusion curves].

By taking peritoneal diffusion curves of several substances characterizing the uraemia it is possible, taking into consideration a creatinine clearance of 0.1 ml X s-1, to calculate the quantity of dialysate necessary for this, regarding also the residual renal function at a differently long duration of the dialysis cycle. Moreover, by this way also the clearances of other investigated substances can be calculated. Apart from a sufficient detoxication optimized duration of the disease and consumption of the dialysate are the advances of the method.

Creatinine↗
PubMed1984

[Peritoneum as dialysis membrane--a morphologic study].

Different histological staining methods allow a deeper insight into the light microscopic structures of the biomembrane peritoneum. To the wellknown model of the peritoneal resistances according to existing results two other resistances shall be added, namely capillary pericytes and the submesothelial basal membrane. The peritoneal interstice, consisting of muscle and collagenic fibres as well as elastica fibres is penetrated by a well-formed network of reticulum fibres. In these cases is to be recognized a primary structure, characterized by compact, moniliform, doubled, screw-like and fenestrated structures, and a secondary structure, which is characterized by a cylindrical arrangement of these structures. This texture of fibres allows according to morphological points of view an intrainterstitial liquid transport in horizontal and vertical direction, which in irregular position of the anyhow scantily existing capillaries of the peritoneum is prerequisite for a regularly appearing transperitoneal liquid and substance transport in direction of the free abdominal cavity as well as vice versa.

Animals↗
PubMed1982

[A new procedure for the revision and reposition of functionless peritoneal dialysis catheters].

The most important requirement for satisfactory transperitoneal dialysis is faultless functioning of the Tenckhoff catheter. Suddenly occurring functional disturbances are often caused by wrong positioning and by envelopment of the catheter by tissue, which require surgical correction. A technique for successfully locating and replacing a transperitoneal catheter by means of an operation laparoscope is described.

Adult↗
PubMed1981

[Observation of the course of 4-year ambulatory peritoneal dialysis in the treatment of chronic uremia].

It is reported on a 4-year chronic peritoneal dialysis due to decompensated retention of substances normally contained in the urine in chronic pyelonephritis. Under a treatment regimen of 3.6 dialyses with 20 1 of wash each satisfying values of creatinine, haemoglobin and total protein in the serum were found. Further a vast normalisation of the blood pressure could be achieved. A series of complications partly repeatedly appearing could be treated successfully. By a diet rich in protein and careful use of the peritoneal dialysis catheter the most dangerous complications of the peritoneal dialysis, loss of protein and peritonitis, did not represent a serious problem.

Ambulatory Care↗
PubMed1980

[Blood detoxication procedures in extra-renal diseases].

In a survey concerning the application of haemodialysis, ultrafiltration, haemofiltration, haemoperfusion and separation of plasma in the treatment of non-renal diseases clinically tested methods are discussed. The therapy of endogenic and exogenic poisonings as well as the removal of hyperhydrations of different genesis using extracorporeal systems can be clarified scientifically with the help of clinical course and laboratory findings. The separation of plasma on membrane opens new possibilities of therapy of above all immunologically conditioned diseases. The valency of the treatment of schizophrenia needs further intensive research concerning etiology and pathogenesis, since the judgment of the success of therapy still underlies too many subjective factors.

Anemia, Sickle Cell↗
PubMed1978

[Clinical and histological studies on the course of glomerulonephritis].

It is reported on 37 patients in whom on the basis of the clinical suspicion of a glomerulonephritis a biopsy of the kidneys was carried out, and after treatment in these patients a rebiopsy was carried out 21 months later in order to examine clinical and histological changes during this period. Hereby could be established that the rebiopsy only six times evoked an apparant improvement, whereas the other cases showed clinical findings or deterioration and only in half the cases a correspondence between clinical and histological developmental tendencies was recognizable. As conclusion indications to rebiopsy are proposed.

Biopsy↗
PubMed1976

[Comparative clinical and histological studies in the diagnosis of isolated proteinuria and hematuria].

In 311 patients with clinical suspicion to glomerulonephritis biopsies of the kidneys were performed. In these cases in 82% the histological or tentative diagnosis, respectively, of a glomerulonephritis could be made. As diseases preceding the glomerulonephritis relapsing tonsillitides are occupying the first place, whereas scarlet fever, otitides, furunculoses and sinusitides were observed more infrequently. Clinically cases of oligosymptomatic glomerulonephritis were more frequently observed than monosymptomatic ones. One fifth of the patients exhibited a restricted renal function or a proteinuria of 3 g/24 hours, in which case proliferatively sclerosing, diffusely proliferative and membranaceous forms occupied the first place.

Adolescent↗