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Biomedical subjects

G Krekeler

Publications and source records attributed to G Krekeler.

At least 19 recordsLinked to original sources

Maxillary sinusfloor elevation and grafting with human demineralized freeze dried bone.

In the continuous search for the ideal grafting material in this study the authors used human demineralized freeze dried bone (DFDB) in the maxillary sinusfloor elevation surgery. In total 30 sinusgrafts were performed in 24 patients. Residual lateral maxillary bone height was less than 8 mm but more than 4 mm. The surgical technique used was according to the description of Tatum (1986). In those 30 grafted sinuses a total of 69 ITI full body screw implants were placed 6 months after grafting. Four sinuses exhibited a prolonged healing time. All implants were loaded 4 months after insertion. No implant losses or failures occurred. The rough surface ITI dental implant appeared to be a suitable implant following sinusgrafting with DFDB. According to the results of this study the limited sinusfloor elevation procedure with DFDB appears to be a clinical reliable pre-implant procedure.

Adult↗

Conventional versus laser-assisted therapy of periimplantitis: a five-year comparative study.

Between 1994 and 1999, 50 patients were treated with either profound parodontopathy (30) or periimplantitis (20). Half of each of the two groups of patients was treated conventionally, and the other half was treated with laser support. Before the operation, microbiological examinations were carried out, in addition to registering the clinical findings and taking x-rays. These procedures were repeated after the operation, and again after 6, 12, 24, 36, 48, and 60 months. The surgical part of therapy for each half of the patient groups included surface decontamination with diode laser light (1-watt output, maximum of 20 seconds) in addition to conventional procedures. The values of the laser-supported therapy were lower than those specified in the relevant literature. The relapse rate of the two diseases (13% for the periimplantitis and 23% for the parodontopathy group) after 5 years was lower than the comparative values of researched literature where decontamination was not included in the therapy. We think that integrating diode laser light decontamination in the approved treatment schemes for periimplantitis and parodontitis contributes considerably to the success of this therapy.

Adult↗

Sinusfloor elevation and grafting with autogenous iliac crest bone.

Insufficient bone height in the posterior area of the maxilla, due to expansion of the maxillary sinus and atrophic reduction of the alveolar process of the maxilla, represents a contra-indication for insertion of dental implants. This anatomic problem can, in many cases, be solved by augmentation of the floor of the maxillary sinus. This surgical technique was introduced by Tatum. The so-called top hinge door method creates a new floor of the maxillary sinus at a more cranial level. Underneath this new floor the existing space is filled with a bone graft. Implantation in the alveolar process with increased bone height allows insertion of dental implants. This sinus grafting technique was used in the present study. In total, 62 sinusfloor elevations were performed with cancellous iliac bone grafts in 42 patients. In those 62 augmented sinuses, 161 ITI screw type implants were inserted. The follow-up was 1-6 years after implantation. In 2 cases infections occurred. One implant needed an extended integration time. No implants were lost. The ITI solid screw implant appears to be a suitable implant following sinusfloor elevation operations, due to its rough surface, its shape and the size of the thread. The sinusfloor elevation procedure with autogenous cancellous bone graft appears to be a valuable and reliable pre-implantological procedure, provided a proper pre-operative investigation and careful surgery are performed. This procedure allows dental implant placement with a high success rate.

Adult↗

[Tooth root length and tooth neck diameter as indicators in sex determination of human teeth].

The length of the dental root and the diameter of the tooth neck are odontometric parameters which to date have rarely been used for the differentiation of the sexes. Teeth of 166 individuals from the early medieval burial ground of Eichstetten (south Germany) were available for examination. A correlation analysis was performed to show the possible dimensional interrelation of teeth which, however, applies only to the dental neck parameters. Using only diameters of the tooth neck and length of dental roots, it was possible to perform a new sex determination for 68 of the 166 individuals. It shows a good coincidence with a traditional sex determination. A traditional sex determination, performed in advance, as well as the archeological assignment of typical sex related grave goods were used for verification. For future sex determination based on teeth, examinations are recommended to be restricted to the six-year molar, the first upper premolar and, in particular, the canine. Also the dental neck diameter proved to be more useful than the crown diameter. Dental root lengths can be neglected. By comparing the results with those of a second Alamannic burial ground it could be established that discriminant analyses performed within the same population are highly congruent.

Female↗

[Dental implants--indications and long-term outcome].

Osteo-integratable dental implant systems were developed 25 years ago. The mean life of such implants is about 20 years when they are properly inserted for the right indications. The most important indication is the edentulous mandible, but also the toothless maxilla, the free-end situation in the case of bridges, and single-tooth replacement. Effective procedures have since been developed for eliminating bone deficits that once excluded the use of implants.

Contraindications↗

Identification of Bacteroides forsythus in subgingival plaque from patients with advanced periodontitis.

Bacteroides forsythus has been associated with destructive adult periodontitis. Up to now, detailed analysis by classical means was hampered by the fastidious nature of the organism. There is hope that the application of molecular detection methods such as indirect immunofluorescence or in situ hybridization (ISH) will allow for more rapid and accurate identification. Here we describe a B. forsythus-specific probe (BFV530), complementary to 16S rRNA, which correctly identified all B. forsythus isolates as confirmed by biochemical, protein, or fatty acid analysis. To assess whether this probe might be suitable for direct identification of B. forsythus in clinical specimens, a total of 92 subgingival plaque samples were analyzed. Fifty-five specimens were tested in parallel by culture, light microscopy, and filter hybridization. Unfortunately, the overall agreement between results of filter hybridization and conventional methods was 70.9% only. We therefore examined 37 new specimens by ISH and indirect immunofluorescence by using fluorescently labeled probe BFV530 or B. forsythus-specific monoclonal antibody 116BF1.2 (kindly provided by R. Gmür, Zurich, Switzerland), respectively. Agreement between these methods was 100%, indicating that ISH with probe BFV530 might be used to accurately identify B. forsythus directly in subgingival plaque samples.

Adult↗

Hemorrhage of the floor of the mouth resulting from lingual perforation during implant placement: a clinical report.

The edentulous mandible provides a frequent indication for oral implants. In many cases implants are placed in the interforaminal region to support fixed prostheses or give retention to removable overdentures. One of the hazards of this seemingly safe surgical area is hemorrhage of the floor of the mouth. In this article, two cases of this life-threatening complication are reported.

Adult↗

Autogenous maxillary bone grafts in conjunction with placement of I.T.I. endosseous implants. A preliminary report.

Small bone defects due to atrophic, traumatic or periodontal bone loss can be grafted with autologous bone grafts taken from the maxillary tuberosity. This study presents a 1-3 years follow-up of 22 patients who were treated according to this technique. Thirty-two implants were placed 6 months after bone grafting. All implants were functioning well at the time of investigation.

Adult↗

Atraumatic surgical technique and implant bed preparation.

The issues of bone necrosis and implant bed congruency are both central to the success or failure of endosseous dental implants to achieve osseointegration. Use of internally irrigated drilling instruments has been postulated to minimize bone necrosis. The ability of the cutting instruments to produce a smooth, congruent implant bed and retain fine bone structures is also critical to achieving primary integration. In the experiment conducted, the use of internally cooled instruments reduced the likelihood of thermal bone damage, particularly when trephine mills were used. Trephine mills were able to retain the fine bone structures of the walls of the implant bed site. No visible degradation occurred from multiple uses of the instruments.

Animals↗

The placement of angled implants in the edentulous maxillae for the use of overdentures.

Although most retention problems of prostheses are concentrated in the mandible, patients have similar problems in the maxillae. Retention of prostheses can be improved by the use of two or four implants, either with retentive anchors or with a bar in the frontal part of the maxillae. The method of planning and placement of I.T.I. Bonefit implants is described.

Dental Implantation, Endosseous↗

Palatal mucosa grafts for oral implant devices.

Oral implants placed in the atrophic mandible often lack sufficient surrounding attached keratinized gingiva. Although mobile mucosa surrounding the implant does not necessarily need to be replaced, many oral surgeons and dentists prefer attached, keratinized gingiva, especially in cases where oral hygiene is imperfect. This article discusses a method of palatal mucosa transplantation to improve the implant recipient site. The clinical results of this method used in 30 patients are reported.

Adult↗

Benefit of Bonefit implant system.

The International Team for Oral Implantology (ITI) Bonefit system has been introduced as an extended and improved system with respect to titanium plasma-sprayed screws and the F-type implant. The clinical results of the Bonefit implant system were at least as good as those of the F-type implant. The Bonefit system, however, offers more indications and applications, especially in crowns and bridgework. Furthermore, the ITI Bonefit system appears to eliminate some of the reported shortcomings of the F-type implant.

Adolescent↗

Synthetic oligodeoxynucleotide probes for the rapid detection of bacteria associated with human periodontitis.

Analysis of the subgingival microflora has recently implicated Actinobacillus (Haemophilus) actinomycetemcomitans and several black Bacteroides species in the aetiology of juvenile, adult and rapidly progressing periodontitis. Rapid bacteriological diagnosis has been hampered by the slow growth and fastidious nature of these bacteria. To construct diagnostic probes, dideoxy sequencing of the 16S rRNA molecules from A. (H.) actinomycetemcomitans, Haemophilus aphrophilus, Bacteroides gingivalis, Bacteroides intermedius subgroup II, Bacteroides asaccharolyticus and several closely related species was performed. Next, oligodeoxynucleotides, complementary to defined regions of the 16S rRNA exhibiting considerable evolutionary divergence, were synthesized for use as molecular probes. In a dot-blot hybridization assay, all strains from each of the species for which probes were constructed were correctly identified, with a detection limit of less than 5 x 10(3) organisms. No cross-hybridization to closely related species (except for H. aphrophilus and Haemophilus paraphrophilus) or contaminating bacteria was observed. Using a modified DNA/RNA hybridization technique, the detection could be performed in less than 12 h, as compared to 2-3 weeks using conventional bacteriological procedures.

Actinobacillus↗