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Biomedical subjects

G Kunit

Publications and source records attributed to G Kunit.

35 records · Page 2Linked to original sources
PubMed1983

Sonographic staging after nephrectomy for tumours.

Sonography for postoperative staging after malignant renal tumours was evaluated in this study based on multiple examinations in 63 patients. Sonography permits a critical examination of the liver, the abdomen in general, the retroperitoneal space, including the renal fossa and solitary kidney. Local recurrences after hypernephroma operation were found in 5.3% and after nephrectomy for renal pelvic carcinoma in 68%. Retroperitoneal lymph node metastases appeared in 17% of the patients operated on renal pelvic carcinoma and in 7.6% after hypernephroma operation. These data indicate that special attention should be drawn to the renal fossa after tumour nephrectomy. The higher incidence of recurrences in the renal fossa, and metastatic lymph node involvement in patients following nephrectomy for renal pelvic carcinoma compared with the situation after hypernephroma operation might be explained by the difference of the lymph drainage between the renal pelvis and renal parenchyma which, in addition, includes a separate ontogenetic development. The majority of secondary lesions in hypernephroma patients occur as lung and bone metastases which have been discovered by conventional X-ray examination. These data are not statistically evaluated in the study.

Adenocarcinoma↗
PubMed1982

Spermatogenesis in men treated with injections of medroxyprogesterone acetate combined with testosterone enanthate.

The effects of a combination of medroxyprogesterone acetate and testosterone enanthate, on the exocrine and endocrine testicular function were examined in adult men. The treatment was carried out with 2 different regimens and lasted for 8 months. Group I received an initial injection of 1000 mg medroxyprogesterone acetate and 500 mg testosterone enanthate followed by monthly maintenance dose of 150 mg medroxyprogesterone acetate and 500 mg testosterone enanthate. In group II, after an initial high dose of 1000 mg medroxyprogesterone acetate and 250 mg testosterone enanthate treatment was given as biweekly injections of 75 mg medroxyprogesterone acetate and 250 mg testosterone enanthate. Complete spermatogenic arrest of variable duration was achieved in all 9 subjects enrolled. Restoration of spermatogenesis occurred in both groups, in a few cases during the treatment, and there was a delay of full recovery of sperm counts up to 5 months after cessation of therapy. None of the subjects enrolled in this study complained of decrease in libido or change in sexual behaviour. Clinical evaluation and measurements of various urine and serum components revealed no significant changes during the treatment period. The dosage and the different administration schedule of the hormone combination described here was inadequate to maintain azoospermia in all subjects during treatment.

Adult↗
PubMed1981

Sonography in blunt renal trauma.

In 27 patients with blunt renal trauma, sonography was used as diagnostic method. In principle, sonography was performed after the urogram. In 15 cases pathological findings were present: 5 subcapsular and perirenal hematomas; 3 ruptured kidneys and 1 renal pedicle injury; in 6 cases pre-existing lesions of the kidneys were present (1 cyst, 3 hydronephrotic kidneys and 2 tumors). A positive urogram and a pathological sonogram lead to the angiography in particular when the possibility of injury of other organs is suspected, or when urographically a nonfunctioning kidney simulates a lesion of the renal pedicle. The adoption of this diagnostic sequence is most economical, it provides the clearest findings and is the least irksome for the patients.

Adolescent↗
PubMed1981

[Surgical management of vesico-renal reflux in adults].

27 units of ureterorenal reflux in adults were operated and analyzed between 1976 and 1980. It was shown that adequate preservation of function in refluxive kidneys with scarring grades I and II can be achieved by means of ureteroneocystostomy after the method of Cohen. The early removal of unilateral refluxive kidneys with high grade scarring is imperative. In cases of bilateral occurrence the indication for operative treatment should depend on the function demonstrated by isotopic investigations.

Adolescent↗
PubMed1980

The effect of chronic administration of a synthetic LH-RH analogue intranasally in cryptorchid boys.

Eighteen boys with either unilateral or bilateral cryptorchidism were treated with a synthetic LH-RH analogue ("D-Leu 6, Des-Gly-10 LH-RH ethylamide") intranasally. The peptide was dissolved in aqueous solution (25 micrograms in 0,2 ml) and administered in the form of nasal drops. The patients were divided in two groups: in group A, 50 micrograms of the synthetic LH-RH analogue were administered intranasally every 48 h for 36 days; in group B same dose was given every 24 h. Additionally, in 4 cases a LH-RH test prior the trial was performed with the same peptide. The nasal administration resulted in a fivefold increase of LH and of FSH plasma concentration in 30 min and in 60 min, respectively. The endocrine profiles for T, LH and FSH were studied in each group over the treatment period and in group B (same dose was given every 24 h) a significant decrease of the LH and FSH plasma levels could be found. The clinical effect of treatment was same in the both groups. In the whole material 44% had either unilateral or bilateral descent of the testis after the therapy.

Administration, Intranasal↗
PubMed1980

[Experiences with neoimplantation of the ureters following Cohen's method (author's transl)].

In the years 1977 to 1979 three operative procedures were used by us to correct vesico-ureteric reflux. The results in relation to 82 re-implanted ureters are presented. The indications for anti-reflux surgery are discussed in relation to the Cohen and Grégoir techniques. The Politano-Leadbetter technique was replaced by the Cohen method. The latter is simpler to perform and has a lower complication rate.

Humans↗
PubMed1979

[Sonographic findings in blunt renal trauma (author's transl)].

The kidneys are beautiful organs for ultrasonography, because of their position, well defined characteristic appearance and excellent acoustic qualities. This is highly important for assessing all pathologies leading to macromorphological changes of the kidneys including these in blunt renal trauma. We could'nt find any paper on this topic in the recent literature available for us. Our own material in renal blunt trauma includes 17 patients. There were no pathological findings in 7, and pathological findings in 10 of them. Sonographic accuracy in severe trauma of the kidney is about 100%, excluding hydronephrotic kidneys, which cannot always be distinguished from a bigger parapelvic cyst. Urogramm resp. Uronephrotomogramm should be performed and studied thoroughly. Exceptions are Iodine allergy and pregnancy.

Child↗
PubMed1979

Ultrasonic diagnosis of the retroperitoneal space.

A precondition for ultrasonic diagnosis of the retroperitoneum is an optimal preparation of the patient to eliminate flatulence in the intestines. If the large vessels of the retroperitoneum are well demarcated, the optimal examination conditions are present. Tumorous and cystic changes of 2 cm or more, can be visualized. Difficulties, however, in the coordination and the differentiation of retroperitoneal tumors from organic tumors (pancreatic tail, splenic and gynecological tumors) can arise. Tumor changes in the lymphatic nodes, the adrenal gland and the sympathetic trunk, tumors in the retroperitoneum from other causes, and aortic aneurysms are discussed.

Adrenal Gland Neoplasms↗
PubMed1979

Renal arterial thrombosis after the contralateral removal of a pelvic kidney.

In a 19-year-old female a pelvic kidney, on the left side, was removed because of recurrent urinary tract infections, severe abdominal complaints and a pathological isotope-nephrography. Following nephrectomy a severe uremia with cerebral edema and pneumonia developed based on a medial necrosis of the artery of the right kidney. After surgical correction the function of the right solitary kidney returned to normal.

Adult↗