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Biomedical subjects

G Kunitsch

Publications and source records attributed to G Kunitsch.

At least 19 recordsLinked to original sources

[Evaluation of air segment plethysmography using computer tomography].

The measurement of tissue volume in the calf area carried out by computer-tomography and planimetry showed a nearly elliptic form, an average bony part of 9.9 ml (9.3%), and an average tissue volume of 97.7 ml (90.7%). When compared with the tissue volume approximation (cylinder formula) the tissue volumes thus specified were too large. The error, depending on the circumference of the calf, was about 5 to 15%. There was a difference of 5% between the venous capacity measured by computer-tomography on the one hand and air segment plethysmography on the other. The reason for this is found in the varying density of veins in the examined area. The application of the sensor on the skin caused an average reduction of 5.4% in total volume and thus in the blood volume of about 59% in the examined area. The pressure-dependent venous capacity was measured with and without application of the sensors on the skin and controlled by computer-tomography. The results showed an average difference of only 2.1%. Thus it is obviously unimportant for the results of the investigation presented, if the venous capacity is measured on the basis of the reduced total volume caused by the application of the sensors on the skin. With regard to the computer-tomographical and planimetrical control and the error of measurement discussed, the results suggest a sufficient precision of the venoextensiometry measuring the pressure-dependent venous capacity.

Blood Volume↗

The value of metrizamide CT cisternography in the diagnosis of CSF fistulae.

Post-traumatic CSF fistulae and those affiliated with tumours on the skull base have so far been investigated by isotope cisternography, fluoresceine tests and polytomography. 12 patients have recently been studied by metrizamide CT cisternography. In acute post-traumatic cases difficulties arise in the differentiation between blood clots and the stream of contrast medium. The method was found to be useful in delayed CSF fistulae and tumour-associated cases.

Brain↗

[Significance of arthrography of the knee joint (author's transl)].

A survey on the double-contrast arthrographie of the knee is given. Speical problems of the method and the interpretation of the films are presented. Besides the delineation of the pathological alterations of the menisci, which is possible in about 85 to 95%, the possibility of delineation of other knee joint damage is discussed, their significance being far beyond that of the meniscal lesions. At last the post-operative changes of the knee joint following meniscectomy are summarized including the evaluation of plain films and repeat arthrography. Own investigations on 117 meniscectomized patients are presented. 35 patients had symptoms, on 23 of them a repeat arthrography could be performed. The symptoms could essentially be explained by meniscal remnants and degeneration of the cartilage at the operated site of the knee.

Arthritis↗

[Which arguments favour radiation therapy in induratio penis plastica? (author's transl)].

Vitamin E and percutaneous irradiation are the most common treatment regimens of Peyronie's disease. This report presents the results of 49 patients irradiated with 137Cs gamma rays. 28 of them had also received Vitamin E. An objective improvement was achieved in 37 patients (75%). Vitamin E did not show any additional benefit. In spite of the fact that these results do not permit an objective evaluation of both treatment regimens, the following advantages of radiotherapy should be considered: a) short treatment time b) low costs c) no serious side effects.

Cesium Radioisotopes↗

[Lumbar myelography with methylglucamine-iocarmate (dimer-x). A critical review of neurological complications (author's transl)].

A critical literature review is presented on the basis of our own clinical experiences with complications and distressing side effects of the lumbar Dimer-X myelography. Severe Complications such as spinal and conuscauda-symptoms, epileptic seizures, amnestic episodes and late palsies of the Abducens nerve in literature range between 1 and 9%. Unspecific side effects which cannot clearly be differentiated from pure post-lumbal puncture complaints are reported to occur in up to 28%. The probably underlying pathogenetic mechanisms are discussed together with former animal experiments which revealed a local toxity of the contrast medium at the central nervous tissue and the surrounding membranes.

Abducens Nerve↗

[The effect of oxyfedrine and intervall training in intermittent claudication (author's transl)].

In 23 patients suffering from intermittent claudication due to chronic occlusions of the femoral artery proved on angiography, a double-blind study was performed to compare the effects of treatment with oxyfedrine and interval-training and of interval-training alone. The claudication distance, physical work capacity and physical work intensity were measured on the treadmill before, during and after 10-weeks training period in each case. After training, the walking ability improved in both groups, however, quantitatively being more pronounced in the oxyfedrine group. In the placebo group, the increase in physical work intensity was mainly caused by the improvement of walking ability in patients with higher levels of performance at the beginning of the training. In the oxyfedrine group, on the other hand, a continuous and regular increase in physical work intensity was found at all levels of performance and during the whole training period. For the differences found, blood supply lowering mechanisms after physical training and improvement of collaterals after combination oxyfedrine and physical training are discussed. The possibility of additive action of the pharmacologic treatment and physical training are pointed out.

Aged↗

[Radiology of portal hypertension (author's transl)].

Description of the applications of radiology to portal hypertension, mainly of the 2 most common conditions, the secondary prehepatic block and the intra-hepatic block in cirrhosis of the liver. In prehepatic block the veins in the splanchnic area which will have to be anastomosed to relieve pressure must be shown. This can be done with direct and indirect spleno-portography and by contrasting the proximal and, possibly, the distal mesenteric veins. For intrahepatic postsinusoidal block of cirrhosis of the liver the portal vein and its major contributaries must be shown. In addition, circulation and pressure in the liver and its surroundings have to be elucidated. For this, catheterisation of the umbilical vein and the veins of the liver are suitable. In addition splenoportography and mesentericography have to be used, when transumbilical portohepatography cannot be done.

Catheterization↗

[Coarctation of the aorta on the plain chest x-ray (author's transl)].

Chest X-rays were analysed in 22 male and 16 female patients (mean age 30.7 years) with coarctation of the aorta. The results were correlated with angiography, haemodynamic pressures and operative findings. The left subclavian artery was prominent in 33 cases, signs indicating a collateral circulation (rib notching, internal mammary artery) were present in 26 cases. In addition there were changes of cardiac and aortic configuration. The least reliable sign was constriction of the aorta due to the stenosis itself. Frequent combinations of X-ray signs were dilatation of the left subclavian artery and a collateral circulation, in addition to signs of increased pressure (n = 25). Less frequently (n = 8) only a dilated subclavian artery and signs of increased pressure were found. The prominence of the subclavian artery was particularly marked in systolic pressure gradients through the stenosis of greater than 40 mm Hg, and the formation of a collateral circulation when average aortic pressure differences above and below the stenosis were less than 40 mm Hg. Collaterals were to be found most frequently with a correlation of 2:1 of the systolic gradient to the mean pressure gradient delta Ps/delta Pm. A very good correlation existed comparing X-ray signs with findings at operation. The diagnosis of coarctation of the aorta can thus be made with sufficient certainty from the plain chest X-ray.

Adolescent↗

[Influence of interval training on the physical capacity and peripheral circulation in patients with intermittent claudication].

Physical performance on treadmill and calf blood flow (venous occlusion plethysmography) were determined in 6 patients with symptoms of intermittent claudication before and after a 10-weeks period of intervall training. Arteriosclerotic occlusions of femoral artery were proved on arteriography in all cases. After training, a significant improvement of the claudication distance and the work performed on the treadmill on an average of 44% were stated, whereas nnd. The peripheral blood flow at rest and after 3 minutes circulatpressed as area under the blood flow curve during reactive hyperaemia) on an average of 54%. The benefits of a controlled home-training program as the necessity of investigation at maximal stress, when assessing the haemodynamic effects of physical training, are pointed out.

Aged↗

[A modification of the Roher-Kahlstorf method for estimating rapid changes in cardiac volume].

A simple roentgenological procedure is described, by which it is possible to measure the heart volume and its alteration during early orthostatic adaptation.--Long distance films are taken in the p.a.-projection using a 70-mm-camera with a frequency of 2 to 4 exposures per second. The length and width and there by the plane of the heart are determined from these films. The mean horizontal depth diameter, that is necessary to calculate the volume of the heart can be gained by indirect means. There is no statistically significant difference between the heart volumes, that have been determined in 12 test persons by the method described, and the commonly used method. -- The alteration of the heart volume in 10 test persons were investigated during acute orthostatic stress. The heart volume, which was 693 +/- 24,8 ml before the orthostatic stress, decreased within 6,9 +/- 1,6 sec statistically significant by 16,5% An influence of the movements of the diaphragm on the heart volume determination could be excluded.

Angiocardiography↗