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Biomedical subjects

G L Ermakova

Publications and source records attributed to G L Ermakova.

At least 19 recordsLinked to original sources

[Hematological dispensary care for the participants in the cleanup of the aftermath of the accident at the Chernobyl Atomic Electric Power Station].

Standard (hemogram, routine biochemical indices) and non-standard hematological parameters reflecting monocytic-macrophagal system (MMS) function and antioxidant defense were investigated in 140 subjects who had worked in radionuclide-contaminated zone after the Chernobyl accident. As shown by measurements of iron serum metabolism, lysozyme, total interferon, CIC, chemiluminescence of venous blood mononuclear leukocytes, MMS in 50% of them underwent negative changes in suppressed antioxidant defense. Standard hematological findings registered abnormalities only in 8-27% of the examinees.

Adult↗

[Nonspecific factors for defense of the body against infection in paraproteinemic hemoblastosis].

The nonspecific defense from heterogeneous agents was sharply suppressed in patients with multiple myeloma. It was, probably, connected with the tumor growth, as well as with the influence on the factors studied of varying circumstances attending the tumor growth, such as renal insufficiency, granulocytopenia, thrombocytopenia, circulation of high-molecular pathologic protein in the blood bed, etc. No principal differences have been detected between the character of immunological disorders in multiple myeloma and Waldenström's macroglobulinemia. We can speak of only the degree of these disorders that, evidently, correlates with the aggressiveness of the process.

Aged↗