Biomedical subjects

G L Kelly

Publications and source records attributed to G L Kelly.

15 recordsLinked to original sources

PubMed2004

Laboratory adaptation of Bactrocera tryoni (Diptera: Tephritidae) decreases mating age and increases protein consumption and number of eggs produced per milligram of protein.

A significant reduction in age of mating occurred during the first four generations (G1-G4) of laboratory adaptation of wild Bactrocera tryoni (Froggatt) and this was associated with the earlier attainment of peak egg load although no significant differences were detected in the peak egg load itself. A long term laboratory (LTL) strain had a significantly earlier mating age and higher peak egg load than flies of wild origin or those from the first four laboratory generations. The amount of protein consumed by females in the first week of adult life was significantly higher in the LTL strain than in flies of wild origin or G1-G4 but there were no significant changes (or only slight changes) with laboratory adaptation in the amounts of protein consumed up to the ages of mating and peak egg load. Laboratory adaptation resulted in no significant changes in egg size, egg dry weight, puparial fresh weight and the dry weight of newly emerged females. The large increase in fecundity with laboratory adaptation is associated with a 4- to 5-fold increase in the rate of conversion of dietary protein to eggs (i.e. eggs produced per mg of protein consumed).

Adaptation, Biological↗

PubMed1991

Childhood depression and suicide.

Recent years have witnessed accumulating evidence that the disorders subsumed under the heading of childhood depression are much more prevalent than used to be believed; that these conditions in prepubertal youngsters are more similar to those disorders occurring in adolescents and adults than was previously believed; that childhood depression can co-exist with many other childhood conditions; and that, although a rare occurrence, suicide is committed by older children. To quote a professional in the child mental health field: It is difficult to see how depression could not be involved in almost every form of psychopathology. The various theories of personality speculate on the existence of unhappy and depressing feelings and cognitions at the core of human development, with ineffective means of dealing with these concerns expressed by abnormalities. . . . Thus it becomes reasonable to argue that depression is everywhere in childhood and adulthood and hence we must be careful to specify under what conditions it is to be regarded as pathological.

Art↗

PubMed1982

Development of a new vascular prosthetic: lessons learned.

In 1972, polytetrafluoroethylene (PTFE) (GoreTex) wire insulation was first implanted into arteries and veins of dogs at the University of Colorado Health Sciences Center in Denver. Subsequent modifications including fibrillar arrangement, wall thickness, and pore size led to the development of a vascular prosthesis with tissue ingrowth, viable neointima, and encouraging patency rates. Tissue culture, surface charge, and platelet studies have all demonstrated the optimal biologic qualities of PTFE grafts. Replacement of one human portal vein by a PTFE graft for invasive carcinoma of the pancreas was strikingly successful. Only unexplained intimal hyperplasia at the arterial anastomotic margins discouraged us from extensive early clinical trials.

Animals↗

PubMed1981

Vascular trauma in the groin: contrast between iliac and femoral injuries.

Vascular injuries to the groin are common and often life-threatening. Injuries above the inguinal ligament, to the iliac system, are associated with a 37 percent mortality. Associated intraabdominal injuries are common. These patients must be identified promptly, given broad-spectrum antibiotics and taken immediately to the operating room for exploration through a midline incision. Injuries below the inguinal ligament are usually to the femoral vessels and are rarely fatal. These patients may be evaluated more extensively before leg exploration. Associated intraabdominal injuries are unusual, but disability from femoral fractures and nerve injuries are common.

Abdominal Injuries↗

PubMed1979

Reassessment of simple cholecystostomy.

Cholecystostomy was performed on 22 patients with acute cholecystitis after partial (13) or complete (9) removal of gallbladder stones. One patient had complementary common-duct drainage. Early mortality occurred in two patients. Three patients with associated cholangitis but intraoperative reflux of cysticduct bile were all treated by cholecystostomy alone and survived. For the poor-risk patient with cholecystitis, cholecystostomy is effective. When there is associated cholangitis and documented cystic-duct patency, cholecystostomy is also sufficient. When accompanying cholangitis is associated with cystic-duct occlusion, choledochotomy and T tube drainage should be added.

Adult↗

PubMed1978

Reoperation after abdominal trauma.

A five year experience with 782 patients requiring laparotomy for trauma is reviewed. Specifically, the 70 patients requiring unplanned reexploration have been studied to delineate the indications for and implications of such repeat laparotomies. The major indications for such reoperation were intraabdominal abscess (45.7 per cent), bleeding (15.5 per cent), peritonitis (12.1 per cent), and small bowel obstruction (8.6 per cent). There were 16 negative reexplorations (13.8 per cent). Overall mortality in the reexplored patients was 21.4 per cent, all victims of gunshot or blunt trauma. Mortality correlated with the number of required reexplorations, being 67 per cent in those requiring four operations. Of the 31 laparotomies performed initially for diffuse or localized intraabdominal sepsis, only 15 were highly suspected, and 13 of these by simple chest x-ray findings. If after laparotomy for repair of intraabdominal trauma a patient fails to meet the anticipated norm of convalescence, a high index of suspicion for early postoperative hemorrhage, or later sepsis, should be maintained. Such patients have far more to gain than lose by reexploration.

Abdomen↗

PubMed1976