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G L Piccinin

Publications and source records attributed to G L Piccinin.

60 records · Page 4Linked to original sources
PubMedDate not supplied

[Articulation disorders in aphasia. Considerations in several clinical cases].

Selective deficit of verbal output not associated to other anomalies of language, represents a syndrome in which articulatory as well as linguistic aspects can be independently affected. The critical lesion for pure articulatory deficit appears to involve left prerolandic cortico-subcortical structures. Nevertheless, in relation to individual differences in cerebral organization, damage in these structures can be responsible for a simultaneous deficit of articulatory and linguistic mechanisms.

Aphasia↗
PubMedDate not supplied

[Bornaprine in the treatment of parkinsonian tremor].

We report the results of a double-blind placebo controlled study of bornaprine, an anticholinergic drug, in the treatment of Parkinson's disease. We studied 17 patients presenting persistent tremor in spite of a stable long-term L-Dopa therapy. The bornaprine, in doses of 8 mg/die, compared with placebo significantly improves tremor. Only mild side effects occurred. We think the bornaprine may be of value in the treatment of parkinsonian tremor.

Antiparkinson Agents↗
PubMedDate not supplied

[Myelopathic patterns of calcification of the posterior longitudinal ligament].

Three patients with calcification of the posterior longitudinal ligament with myelopathy are reported and discussed. This condition which is frequent in Japan is rarely described in the western population. Such calcification is not only a radiographic finding but is a progressing phenomenon which may extend to compressive lesions of the spinal cord. All patients with calcification of the posterior longitudinal ligament should be fully studied neurologically and followed up.

Calcinosis↗
PubMedDate not supplied

[Treatment of tardive dyskinesia caused by neuroleptics].

There are at least four phenomenologically different types of movement disorders that fall under the rubric of tardive dyskinesia: a) classical TD which is choreatic in speed of movement and stereotypic in pattern, b) tardive akathisia, c) withdrawal emergent syndrome, which presents as true chorea and d) tardive dystonia which presents with dystonic movement and postures. This paper reviews the main treatments of tardive dyskinesia. The drugs utilized have been considered according to their mechanism of action.

Antipsychotic Agents↗
PubMedDate not supplied

[Evaluation of intellectual functions in patients with Parkinson's disease. Bibliographic review].

A literature review shows that patients affected by Parkinson's disease present an intellectual impairment more frequently than the comparably aged population. Such impairment has been related to several factors (age, arteriosclerosis, motor difficulties, depression, dopaminergic therapy, cortical and/or subcortical lesions). Parkinsonian dementia may be caused by the extent of the degenerative process. Our own results show that parkinsonian patients with dementia are different from nondemented ones with the following features: a) a more marked bradykinesia b) a more severe extrapyramidal picture c) a progressive unresponsiveness to levodopa in a shorter time. It seems possible that there is a Parkinson syndrome characterized, clinically, by an intellectual impairment with a poor prognosis quoad valetudinem, and, anatomically, with multiple cortical and subcortical lesions. Such syndrome may be a "transition" form between Parkinson disease and senile-presenile dementia.

Atrophy↗