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Biomedical subjects

G L Scott

Publications and source records attributed to G L Scott.

At least 55 records · Page 3Linked to original sources

Genetic mechanisms determining the central visual pathways of mice.

Albino mammals have abnormal visual pathways. "Flecked" mice have a variegated pigment distribution, with roughly half the cells normally pigmented and half albino. They do not show the albino abnormality in the visual pathways. The gene at the albino locus, which determines the course of the visual pathways must, thus, have an extracellular action.

Albinism↗

An evaluation of the Monosticon rapid slide test diagnosis of infectious mononucleosis.

A new rapid slide test for the detection of infectious mononucleosis heterophile antibody has been compared with the Paul-Bunnell absorption test. Out of 200 sera, 46 were seropositive for infectious mononucleosis by the Paul-Bunnell test and 43 of these were detected by the Monosticon test; the three Monosticon-negative sera were of low titre. There was no problem with false positive reactions due to heterophile antibody not specific for infectious mononucleosis.

Animals↗

Autoimmune haemolytic anaemia and mefenamic acid therapy.

Three patients developed autoimmune haemolytic anaemia while being treated with mefenamic acid. In each case the autoimmune haemolytic anaemia was of the warm antibody gammaG type, and the antibodies had some rhesus specificity. All three patients recovered when the drug was withdrawn.Attempts to inhibit or enhance the activity of the antibody in vitro were unsuccessful.Direct antihuman globulin tests were made in.the red cells of 36 patients receiving long-term mefenamic acid therapy, but only one was found to be transitorily positive.

Anemia, Hemolytic, Autoimmune↗