Biomedical subjects

G L Wylie

Publications and source records attributed to G L Wylie.

3 recordsLinked to original sources

PubMed1995

Validity and reliability of the twenty-eight-joint count for the assessment of rheumatoid arthritis activity.

OBJECTIVE: To investigate the validity of the 28-joint count for assessment of joint involvement in patients with rheumatoid arthritis (RA). METHODS: Joint involvement as determined by the 28- and the 66/68-joint count was compared using data from 735 prospectively studied RA patients. RESULTS: The joints included in the 28-joint count were more commonly involved than other joints, and findings from the 28-joint count correlated highly with those from the 66/68-joint count in all analyses. CONCLUSION: The 28-joint count is a reliable and valid measure for joint assessment. It is easier to perform than the 66/68-joint count, and it addresses the joints that are critically involved.

Arthritis, Rheumatoid↗

PubMed1987

Supersensitivity of d-amphetamine-induced hyperthermia in rats following continuous treatment with neuroleptics.

Following short term treatments with the neuroleptic drugs haloperidol, chlorpromazine and oxypertine, there was an increase in the sensitivity of rats to the hyperthermic effects of d-amphetamine. There was no significant difference in the body temperature of control and neuroleptic-treated rats prior to challenge with d-amphetamine. No change in the maximal hyperthermic response was observed. It is possible that these responses may be related to the neuroleptic malignant syndrome occasionally observed in human patients following short term neuroleptic treatments.

Animals↗

PubMed1968

Jenner museum.

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England↗