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G Languillat

Publications and source records attributed to G Languillat.

15 recordsLinked to original sources
PubMed1978

[Serum proteins and erythrocyte enzymes. Evaluation of frequencies in 2 populations in the Gabon].

The results of the electrophoretic phenotyping of two serum groups (C'3 and Transferrine) and seven red cell enzymes (PAc, PGM, AK, ADA, 6PGD, sGPT and Est D) in two groups of negroes from Gabon are presented. The frequencies are in the normal range observed for African populations except for acid phosphatase in Southern Africa; Khoisan people have frequencies of the "Negroe allele R" higher than in any other population of the world. In Obamba and Bateke populations frequencies of Pr is 0.013.

Adenosine Deaminase↗
PubMed1978

Implications of heterophile antigens in immunological infertility in males.

Immunological study was conducted on serum and hydrocel fluids from males belonging to an equatorial African population heavily contaiminated by Filaria and Schistosoma. Anti-spermatozoa antibodies were detected by agglutination in 31 of 64 sera and 24 of 60 fluids, and by cytotoxicity in 19 of 64 sera and 8 of 60 fluids. Antinuclear antibodies were detected in 21 of 64 sera and 8 of 60 fluids. However, the titers of these antibodies were low, as were the frequency and titers of other tissues antibodies. The appearance of antispermatozoa antibodies is also correlated with extensive skin burns and infection by Pseudomonas aeruginosa or severe Candidiasis.

Africa↗
PubMed1977

[Etiological study of low fertility in eastern Gaboon. III. Filarial endemicity (Loa loa, D. perstans). Prevalence of microfilariae in hydroceles (author's transl)].

During an inquiry performed in Gaboon the prevalence of hydroceles had led to puncture systematically every vaginal flow. 68 fluids were so collected at the end of the inquiry. Subsequently the statistical analysis of the results in men seems to suggest a correlation between microfilaremia (Loa loa and D. perstans) and the prevalence of hydroceles. Microfilariae were found in 77% according to the following distribution: Loa loa seldom diagnosed in this kind of flow were detected in 10%; D. perstans although never reported so far in hydrocele fluids appeared to be present in 62%. O. volvulus more currently referred to in hydrocele liquids were scarcely traced.

Adult↗
PubMed1977

[Etiological study of low fertility in eastern Gaboon. I. Scheme and first findings (author's transl)].

The etiological study conducted in 1975 in Haut-Ogooué and Ogooué-Lolo included 1,548 patients male and female. In the 21 investigated areas the patients were asked questions and examined by a medical team which took swabs so that bacterial, parastic, immunological and genetical assays could be carried out. The object of this article is to review the feasibility of such a local inquiry and state the first findings. Abnormalities of the epididymis are more commonly verified in non-fertile men. Microfilaremia is related to the presence of hydroceles and epididymis lesions. It shows more often in men with less than 3 children. The authors do not refer to any of physiopathology to explain these findings which need to be ascertained in further inquiries.

Adult↗
PubMed1977

[Etiological study of low fertility in eastern Gaboon. II. Results according to the geographical distribution and the ethnic group (author's transl)].

An epidemiological study was conducted in Haut-Ogooué and Ogooué-Lolo, and included 875 men and 673 women. The purpose of this article is to precise the geographical distribution of the factors related to low fertility, and to verify the stability of the etiological relations according to the region, the place of residence and the ethny. Among men, hydroceles and epididym lesions are more frequent in Ogooué-Lolo, in small villages, and in forest areas. Microfilariae Loa-loa and D. perstans has the same distribution. In both regions and what ever the type of residence (town or village), the epididym lesions are more frequent in non fertile men, microfilariae is linked with genital lesions and is more seldom found in men who are the fathers of more than two children. Among women, leukorrheas, pelvic pains, and adnexal masses are related to low fertility, what ever the place of residence is.

Adult↗
PubMed1976

[Toxoplasmosis and chronic myeloid leukemia].

A patient suffering from chronic myeloid leukemia and used as a donor of leucocytes was found to have toxoplasmosis associated with a high level of IgG without an elevation of IgM which was maintained for several months. This case raises several points for discussion. Toxoplasmosis is a frequent complication of malignant hematological disease, it is often severe with neurological complications in more than half the patients affected. It is often difficult to diagnose. The parasite is arduous to isolate and serology is problematic to interpretate without reference to previous samples. This suggests it would be wise to measure the titre of anti-toxoplasma antibodies as part of the initial investigations of every malignant hemopathy and to repeat the measurements during the evolution of the disease. Any patient showing a high serological titre, even though it is stable and without IgM should be given systematically a specific treatment for toxoplasmosis, for as in the patient presented in this paper, such a serological picture is compatible with an increasing infection. The frequence of high serological titres seems to be greater among patients suffering from chronic myeloid leukemia than among another people. Then, transfusion of leucocytes of such patients may be the source of parasite transmission; this paper relates one case of post-transfusional toxoplasmosis.

Antibodies↗
PubMedDate not supplied

[The average degree of parasitosis, a criterion for evaluation of the geohelminthic contamination of a population, and for application of santiary measures].

The severity of ascaridiasis in a region depends first of all on the degree of pollution by ascaris ova of the environemtn and consquently on the per diem output of ascaris ova in the stools. Therefore, the importance of ascaridiasis as an endemic disease, depends of course upon the number of positive cases, their prevalence, but still more, it depends upon the intensity of the infection of the diseased population (global parasitic discharge). Practically, this concept of global parasitic discharge is expressed by the number of ascaris ova expelled per gram and per day by a sample of the considered population. The mean parasitic discharge is the quotient of the global parasitic discharge through the number of positive cases of the sample. An epidemiological survey and a mass chemotherapy test at La Réunion has showed us that the conept of global parasitic discharge is a more representative reliable and sensitive measuring method than prevalence, to evaluate the gravity of endemic ascaridiasis and its variations.

Animals↗
PubMedDate not supplied

[Toxoplasmosis in Eastern Gabon. Results of a serologic survey].

1,448 sera taken from individuals of various places of South-Eastern Gabon have been studied by means of indirect immunofluorescence and Fulton direct agglutination associated with 2-mercapto-ethanol test, 52.6% contained antitoxiplasmic antibodies. This study showed that toxoplasmic infection occurs early in both sexes, that it is more frequent in men (57.9%) than in women (45.4%), that the Ogooué-Lolo province is more contaminated (62.6%) than the High Ogooué province (49.6%). It seems that prevalence differences are less dependent upon the telluric elimate than upon other factors, which remain to find.

Adolescent↗
PubMedDate not supplied

[A serological survey of arboviruses in Gabon].

Serological studies for arbovirus antibodies were carried out on 1.279 human serum specimens collected from adults in south-eastern part of Gabon from June to September 1975 during a multipurpose epidemiological survey. More than 80% of the population surveyed have neutralizing antibodies for yellow fever virus as consequence of mass vaccination campaign. Chikungunya, Zika, Wesselsbron and Koutango virus showed some activity, especially in woodland savannahs.

Adolescent↗
PubMedDate not supplied

[Intestinal parasitism in eastern Gabon].

A survey of 1,548 stools samples carried out in Gabon showed in the adult population a parasitism ratio of about 100%. Among the protozoa, D. fragilis was found in 0.3% of the cases. In contradiction with the usual observations in tropical Africa, A. lumbricoides and T. trichiura infestation is very high in the villages. The demonstration of S. intercalatum in almost every place of the survey and an important focus at Okondja proves the extension of this bilharziosis.

Adult↗