PubMed Health⌕ Search

Biomedical subjects

G Le Gonidec

Publications and source records attributed to G Le Gonidec.

27 records · Page 2Linked to original sources
PubMedDate not supplied

[Arboviral diseases in South-West Pacific islands (author's transl)].

Islands of the south-west Pacific area belong to the melanesian group, excepted Niue, Tonga, Wallis and Futuna which are polynesian. Through New Guinea, there is a geographic relation to the eastern part of Australia, rich of 42 arbovirus types. Dengue and Ross River fever are the most important arboviral diseases in the region; both affect islanders after introduction of virus by travellers to localities where efficient vectors are present. Dengue types 1, 2 and 4 were isolated from man and from mosquitoes in this area. Successive outbreaks, transmitted by Aedes aegypti or by Ae. polynesiensis, resulted in thousands of cases with a few fatal hemorrhagic forms. Ross River virus, responsible of epidemic polyarthritis, evaded in 1979, from Australia to Fidji, Wallis, Futuna and New Caledonia. Suspected vectors are Aedes vigilax and Culex annulirostris. Aedes aegypti and Ae. polynesiensis are also possible carriers. Murray Valley encephalitis virus caused severe outbreaks in Australia and fatal cases in New Guinea; it is a possible invader when Culex annulirostris is abundant. Expansion of arboviral diseases is a major epidemiological problem in south-west Pacific islands. Research work on pathogeny and vectors control must be intensified in this area.

Animals↗
PubMedDate not supplied

[Assay of rabbit anti-thermolabile enterotoxin antibodies from Escherichia coli by an immunoenzyme technic].

The titration of rabbit anti-Escherichia coli heat-labile enterotoxin antibodies by an immunosorbent assay (ELISA) generally uses a GM1 coating step to lend specificity to the ELISA reaction at a time when the method is tempered by a lack of purified E. coli toxin. We have developed an adsorption method of the toxin to the polystyrene in order to simplify the technique. Three different immunosorbent preparations were tested to determine which of them yielded the most sensitive results.

Animals↗
PubMedDate not supplied

[Isolation of a strain of Mokola virus in Cameroon (author's transl)].

A strain of Mokola virus has been isolated in Cameroon from a shrew (Crocidura sp.). In Nigeria, where the virus was isolated for the first time, two human cases with one death were reported. The possibility of transmission of this virus by the bite of an arthropod is discussed.

Animals↗
PubMedDate not supplied

[On an outbreak caused by dengue type 4 virus, in Thio, New Caledonia. Epidemiological and clinical aspects (author's transl)].

After imported cases, a dengue outbreak, caused by type 4 virus, affected 11 per cent of the habitants of Thio, New Caledonia. Distribution of cases by sex, by ethnic and age group, by locality and by week is established on cases confirmed by serology and/or by virus isolation. Clinical aspect was classical but liver and digestive tract of patients were frequently affected. Five haemorrhagic forms were observed. Aedes aegypti was found in each visited house; pooled specimens were found infected by type 4 virus.

Adolescent↗
PubMedDate not supplied

[Prevalence of diabetes mellitus and glucose tolerance abnormality in Melanesians and subjects of Polynesian descent in the rural areas of New Caledonia and at Ouvea (Loyalty Islands)].

The screening of different ethnic groups who live in the same natural system have enabled the authors to study interaction between genetic and environmental factors as a part of etiology of diabetes mellitus. In New Caledonian country areas, the prevalences of glucose tolerance abnormality (GTA) and diabetes mellitus (DM) have been higher with people of polynesian descent than with Melanesians. GTA 7.6 p. ct. versus 5.1 p. ct. DM 6.5 p. ct. versus 2.2 p. ct. The prevalence of these combined diseases have been 14 p. ct. with the Polynesians and 7.2 p. ct. with Melanesians. These two ethnic groups have shown mean ages and obesity rates similar enough to lead the authors to deny these two factors a major part in the difference between the ethnic prevalences of DM. Besides, the mean plasmatic glycemia two hours after a dose of glucose and the relative risk of DM and GTA according to age and obesity rate have shown that the slight differences between these groups are not involved in the different prevalences of DM. This inter-ethnic difference may be due to genetic factors. However, some environment linked factors besides obesity (such as diet and daily life activity) may share a major part in this difference.

Adult↗
PubMedDate not supplied

[Epidemiological data on amebiasis in New Caledonia].

The present study permits to set up the following conclusions: A) The hygienic level of New-Caledonia and Dependences, concerning both running water feeding and installation of water-closets inside housings, is extremely disparate according to the parishes. On that account, the hygienic level is low on the East Coast of the "Grande-Terre" and in the islands. Most of European inhabitants are found in the district of Noumea whereas Melanesians live in tribes mainly on the East Coast and in the islands. Therefore, there is a real difference of hygienic level between the two main ethnic groups.

Adolescent↗
PubMedDate not supplied

[A dengue epidemic at Futuna].

During an outbreak occuring in Futuna (Horne Islands) from October 1976 to January 1977, II strains quite similar to dengue virus type I were isolated from blood of patients in acute phase. Immunitary responses were noted on 8/12 paired sera submitted to IH test; 4/17 serum samples showed antibody titer presumptive of a recent infection. Entomological survey gave evidence that virus was transmitted by Aedes polynesiensis and confirmed that Futuna is free of A.E. aegypti; other species found were: Culex annulirostris, C. pipiens fatigans, C. sitiens. A viral strain was isolated from Ae. polynesiensis only.

Adolescent↗