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Biomedical subjects

G Lewith

Publications and source records attributed to G Lewith.

12 recordsLinked to original sources

The effect of acupuncture on nonallergic rhinitis: a controlled pilot study.

The purpose of this pilot project was to evaluate the immediate effects of real acupuncture compared with two placebo controls (sham acupuncture and mock transcutaneous electrical nerve stimulation) in the treatment of nonallergic rhinitis patients. These three treatments were given in a nonrandomized order to the same patients at weekly intervals. Real acupuncture showed an improvement in nasal airways resistance after treatment in 9 of 13 patients, sham acupuncture in 2 of 9, and mock transcutaneous electrical nerve stimulation in 3 of 10 patients. With the exception of improvement in a minimal cross-sectional area (measured by acoustic rhinometry) in the real acupuncture group following treatment, the outcome was not statistically significant. This pilot study raised a number of issues related to the effects of acupuncture in nonallergic rhinitis that must be addressed by a study involving more patients in which the order of treatment is randomized and the two placebo control treatments are evaluated in relation to their credibility.

Acupuncture Therapy

How should we research unconventional therapies? A panel report from the Conference on Complementary and Alternative Medicine Research Methodology, National Institutes of Health.

Research in unconventional medicine requires a number of different questions to build up a "mosaic" of evidence. Choice of research design depends on the question being asked and is independent of the therapy under investigation. Despite the doubts of some practitioners, randomized trials are of value for determining certain questions in alternative medicine.

Complementary Therapies

Double-blind, placebo-controlled, randomized clinical trial of homoeopathic arnica C30 for pain and infection after total abdominal hysterectomy.

Homoeopathic potencies of arnica have been used for many years to aid postoperative recovery. The effects of arnica C30 on pain and postoperative recovery after total abdominal hysterectomy were evaluated in a double-blind, randomized, controlled study. Of 93 women entered into the study, 20 did not complete protocol treatment: nine were excluded because they failed to comply with the protocol, nine had their operations cancelled or changed within 24 h and two had to be withdrawn because of the recurrence of previously chronic painful conditions. Those who did not complete protocol treatment were equally divided between the arnica (nine patients) and placebo groups (11 patients). 73 patients completed the study, of whom 35 received placebo and 38 received arnica C30. The placebo group had a greater median age and the arnica group had slightly longer operations; nevertheless, no significant difference between the two groups could be demonstrated. We conclude that arnica in homoeopathic potency had no effect on postoperative recovery in the context of our study.

Adult

Placebo controls for acupuncture studies.

Many studies of acupuncture treatment are seriously flawed by methodological problems. Poor design, inadequate measures and statistical analysis, lack of follow-up data and sub-standard treatment are all too common. However, the major problem, which many investigators consider to be still unresolved, is the definition of an appropriate placebo control. The use of inappropriate placebo controls has bedeviled acupuncture research and led to serious misinterpretation of the results of clinical trials. While a number of different solutions have been proposed there is, as yet, no agreed way of assessing the adequacy of control conditions or of deciding which placebo to use in a particular trial. We propose that assessing the credibility of treatments and control conditions may provide a way forward to a more rigorous, consensus approach.

Acupuncture Therapy

Complementary medicine and the general practitioner.

The attitudes to complementary medicine of a random sample of general practitioners in Avon were assessed. A questionnaire was sent to 200 general practitioners, of whom 145 responded. The treatments studied were acupuncture, homoeopathy, herbal medicine, spinal manipulation, faith healing, and hypnosis. Of the 145 general practitioners, 55 (38%) had received some training in complementary medicine and 22 (15%) wished to arrange training. Overall, general practitioners knew little about the techniques of complementary medicine. Despite this 86 doctors (59%) thought that the complementary techniques being assessed were useful to their patients: 110 (76%) had referred patients for this type of treatment over the past year to medically qualified colleagues and 104 (72%) had referred patients to non-medically qualified practitioners. Most (93%) of those who responded believed that complementary practitioners needed statutory regulation; only 3% thought that they should be banned. The method of regulation most favoured was through a central and independent national body. General practitioners' views about complementary techniques were most influenced (in a positive manner) by observed benefits to their patients (41%) and personal or family experience of benefit (38%). The results of the study show a surprisingly high interest in complementary medicine among general practitioners in the Avon area.

Attitude of Health Personnel

Acupuncture.

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Acupuncture Therapy

Biochemical anomalies of the nephrotic syndrome.

The nephrotic syndrome is the only hypoalbuminaemic state frequently associated with hyperlipidaemia. In the presence of a negative nitrogen balance, hyperlipidaemia is metabolically inappropriate and reflects the result of persistent breakaway from free fatty acid control. This lipid abnormality may result in the premature development of ischaemic heart disease in patients in whom it is not possible to control the primary renal abnormality. The authors suggest that future work should be directed towards thyroxine and insulin metabolism in nephrotic states.

Animals