[Metastasis of a melanoma in the breast].
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Biomedical subjects
Publications and source records attributed to G Liszka.
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The authors briefly summarize the most important characteristics of the female breast tuberculosis. They base their data on 7 histologically verified cases as well as on 2 other cases which, in view of the course of disease, were suspected to be breast tuberculosis. The various courses of disease as well as the difficulties in its differential diagnostic are described.
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Authors report on bone metastases by 8 female patients with mamma carcinoma rarely occurring according to the literature. By the first patient a metastasis to the zygomatic bone and to the maxilla, by a second to the corpus mandibuale, by a third to the ascending branch of mandibula was encountered. The fourth patient showed metastasis at the distal end of radius and in the carpal bones, the fifth in the midthird part of tibial diaphysis, the sixth in the I, and II, cuneiform bone, the seventh in the carpal and metacarpal, tarsal and metatarsal bones respectively, the eighth in the calcaneus. In all the above cases previously metastases to other bones (as spine, pelvis etc.) have been noted. This means that in course of the disease the metastases of "rare localisation" appear in a later period.
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Authors state that in osteosarcoma the measure of mineralization of the tumorous osteoid can be precisely assessed with CT. Hounsfield Units (H.U.) values < 300 demonstrate tumorous osteoids not yet mineralized. Over this limit, however, there is a linear correlation between H.U. values and the extent of mineralization. Since CT detects only tumorous osteoids and demonstrates its measure of mineralization, it does not provide information about the tumour cell components. Consequently, it is not a suitable tool for the assessment of tumour response to neoadjuvant chemotherapy. CT has, however, some advantages over conventional radiographic estimation of tumour extent and detection of tumorous osteoid before mineralization. Because of this diagnostic power, CT is indispensable in limb salving surgeries when the level of amputation is to be determined.