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G Lorenzon

Publications and source records attributed to G Lorenzon.

10 recordsLinked to original sources

[Ultrasonic study of the dimensions of the common bile duct in various postures].

To date, the importance of patient position has not been considered in defining the normal range of the internal diameter of the main bile duct. The authors examined 160 patients to verify if significant changes in the internal diameter of the main bile duct take place when changing patient position. In 20/160 cases (12.5%) internal diameter was observed to decrease by greater than 1 mm, in 6/160 cases (3.75%) by greater than 2 mm. These changes were found more often in cholecystectomized patients and were mostly associated with an increase in the max absolute caliber of the main bile duct. Therefore, postural changes (dorsal decubitus, left lateral decubitus, upright position) of the patient are important factors when calculating max internal diameter of the main bile duct. Moreover, postural changes may play an analogous role to functional tests.

Common Bile Duct

[Hepatic echography in acute viral hepatitis].

Reports on cholecystic alterations during acute viral hepatitis are more and more frequent; the pathogenesis and clinical meaning of these alterations are still debated. Consensual periportal lymphnode enlargement has been not yet reported. The authors describe four cases of acute viral hepatitis in which US showed alterations of cholecystic walls and/or contents; in two cases enlarged periportal lymphnodes were demonstrated too. Later US exams showed a complete regression of both cholecystic and lymphnodal lesions. Clinical findings and laboratory out-comes are evaluated; the connection of US results with hepatitis and its meaning are discussed. The causes of cholecystic alterations are still questionable; they might be related to blood disorders or to an increased portal pressure, or else they might be considered as phlogistic lesions. The authors conclude that both cholecystic and lymphnodal alterations have a phlogistic nature; moreover, they are not related to a particular evolution of hepatitis. The importance of distinguishing cholecystic alterations from different pathologies is stressed.

Adult

Metabolism in the rat of cadmium biocomplexes from edible mussel exposed to 109CdCl2.

The metabolism in the rat of 109Cd biocomplexes present in the tissues of the edible mussel Mytilus galloprovincialis, previously exposed to 109CdCl2, was studied. The tissue distribution and binding of 109Cd were compared to those caused by an equal dose of 109Cd as CdCl2 or rat liver Cd-metallothionein. Administration of mussel 109Cd to rats resulted in an initial accumulation of 109Cd in the kidneys due to the presence of 109Cd-metallothionein, which constituted 25% of the 109Cd in the tissues of the mussels. Other 109Cd biocomplexes present in the mussel tissues were metabolized in the rat in a way similar to that of inorganic cadmium, i.e., initial accumulation in the liver. These findings indicate that the ingestion of seafood rich in metallothionein may give rise to a faster increase of renal cadmium levels than the consumption of a similar amount of inorganic cadmium.

Animals

[Ultrasonic diagnosis in the study of primary hyperparathyroidism].

Ultrasonography (US) of parathyroid glands was performed in 56 patients with clinic and/or laboratory findings diagnostic or strongly suggesting a primary hyperparathyroidism. In 42 cases CT and in 8 US-guided fine needle biopsy (FNB) were performed. Surgical or autoptic confirmation was obtained in 34 patients. In controlled cases US yielded an overall sensibility of 88.46%, specificity of 95.14% and accuracy of 94.58% in identifying enlarged parathyroid glands. Doubtful US findings can be due to atypical pattern or site and associated thyroid pathology: in these cases, also in our experience, US-guided FNB can be usefully employed. US was more accurate than CT in detecting small size glands. In our opinion CT is mandatory only in negative US and/or scintigraphic cases. According to some clinical and surgical problems US may have a localizing or diagnostic role.

Adenoma

[504 implantations of aortic valve prostheses].

The results in 504 patients operated with aortic valve replacement are reported. In 153 patients other associated valvular diseases or complications were present. The mortality in non complicated case was 3%. The long term mortality (1--14 years) was 4%. The results and indications are discussed.

Adolescent

Salivary gland echography in primary and secondary Sjögren's syndrome.

A series of different ultrasonographic abnormalities detected by salivary gland echography (SGE) were investigated for their discriminant power for Sjögren's syndrome (SS) in 53 patients with either primary SS (n = 27) or secondary SS (n = 26), as well as in 90 controls. Among the controls, 26 suffered from dry mouth and/or recurrent or persistent swelling of at least one parotid or submandibular gland due to other selected disorders, while 64 were healthy, asymptomatic subjects. Mild, evident or gross inhomogeneous parenchymal patterns were the only variables selected by stepwise discriminant analysis, when comparing patients to controls. However, a mild submandibular inhomogeneity did not prove useful for such a discrimination. Based on these data, a simplified evaluation and standardised quantification of salivary involvement, as detected by SGE, is proposed using an echographic score (range 0 to 6) which assigns points to the different degrees of glandular inhomogeneity. Score values above 0 showed a sensitivity of 88.8% in primary SS and of 53.8% in secondary SS, as well as a specificity of 84.6% and of 92.2% with respect to either symptomatic or healthy controls. The lower sensitivity of SGE for patients with secondary SS presumably was a result of their milder salivary involvement.

Adult