Prenatal US detection of cerebral ventricular enlargement in a case of tuberous sclerosis.
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Biomedical subjects
Publications and source records attributed to G Lucigrai.
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Ultrasonography is currently the method of choice to examine the pediatric patient because it is widely available, noninvasive and inexpensive. Particularly, Doppler US is the method of choice to study renal artery stenoses, which are among the most frequent causes of arterial hypertension in children, in both renal allografts and native kidneys. This study was aimed at investigating the value of the indirect signs of stenosis observed during the assessment of intrarenal vessels--i.e., changes in the waveform, resistive index and acceleration index. We examined 63 renal allograft recipients and a 12-year-old boy with a native kidney and arterial hypertension. In all cases the Doppler curves of the intrarenal vessels were studied both qualitatively and quantitatively. In this paper we report on 5 cases (4 allografts and 1 native kidney) with major waveform changes in the downstream renal circulation. Our findings confirmed the resistive index and the acceleration index measured with Doppler US in the intrarenal vessels to be major diagnostic tools in renal artery stenoses in the pediatric patient when the renal arteries are difficult to assess. However, the technique exhibits some limitations and allows an unquestionable diagnosis only in severe stenoses.
The sonographic changes in a 30-day-old infant with hemimegalencephaly are reported and compared with the CT and MRI findings. Sonography demonstrated the characteristic anomaly of the white matter not shown until later by CT and MRI.
Following a few comments regarding the historical development, preliminary definitions and early studies on battered child syndrome, the Authors give an overall clinical semeiological picture, focusing on the anatomo-radiological characteristics of the most common bone and non-bone lesions. In addition traditional (X-ray) and more advanced methods of image diagnosis (ultrasonography, CT, RM) are examined and their utility in the study of the battered child is evaluated.
A patient of 12 suffering from aneurysmal cyst of the ischium was studied with traditional radiology, computed tomography (CT) and magnetic resonance imaging (MRI). The advantages of MRI in the study of this pathology compared to traditional radiography and CT are assessed. It was shown that the CT and MRI techniques are superior to standard X-ray examinations in anatomic definition and in evaluating the lesions's relationships with neighbouring structures and, in particular, that MRI is superior to CT in extension.
This study evaluates the importance of magnetic resonance imaging (MR) in the exploration of the abdomen in a case of non-Hodgkin lymphoma diagnosed in a 14-year-old boy. Results are compared with those obtained using two widely used diagnostic methods: CT and ultrasonography (US). US revealed a prevalent involvement of the spleen, whereas CT showed a marked hepatic infiltration. The role of MR seems important because it allowed the contemporary and careful evaluation of hepatolienal involvement. The main advantages and drawbacks of using MR in pediatrics, and in particular in the study of the metastatic involvement of hypochondriac organs are discussed.
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We have reviewed 5 cases of Caroli's disease, studied from 1982 to 1987, in order to define the validity of its sonographic signs. The "intraluminal portal vein" sign, found in all the cases, is emphasized. This sign may be easily identified and it is never encountered in other diseases. Recessive polycystic kidney disease was present in 3 cases, and congenital hepatic fibrosis was demonstrated in the 2 cases studied by liver biopsy.
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We describe a case of congenital non-obstructive dilatation of the hepatic bile ducts (Caroli disease). The accuracy of ultrasound for the diagnosis of this syndrome is pointed out. Ultrasound scan can be carried out easily and with a remarkable imaging precision. The ultrasonographic patterns consist of both evident dilatation of the ducts and characteristic protrusions connecting the ductal walls to intraluminal portal branches (bridging). These sonographic findings confirm the etiopathogenetic hypothesis according to which Caroli disease is a result of the blockage of the bile ducts development. Moreover, we underline the efficacy of ursodeoxycholic acid in the treatment of the chronic cholestasis, always present in this disease.
INTRODUCTION: Early slipped capital femoral epiphysis (ESCFE) can be treated surgically, with excellent results, if it is diagnosed in its initial stage; however, the rate of late or missed diagnoses remains surprisingly high. PURPOSE: We compared radiography, US and MR sensitivity in ESCFE diagnosis. MATERIAL AND METHODS: We examined 21 symptomatic overweight patients (15 boys and 6 girls) aged 9 to 15 years with anteroposterior radiographs; frog leg images were not acquired in 3 cases only. US was performed in 19 cases and the images acquired with 5-7.5 MHz probes on the sagittal plane parallel to the femoral neck. MRI was performed in 9 cases, with coronal and sagittal T1 SE and T2* GE images. RESULTS: Our sensitivity rates were 66% for anteroposterior radiography (6 false negatives), 80% for combined anteroposterior and frog leg images (3 false negatives), 95% for US (1 false negative) and 88% for MRI (1 false negative). DISCUSSION AND CONCLUSION: We believe that US is the method of choice in ESCFE diagnosis; if it is negative, but pain persists, MRI should be performed.