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Biomedical subjects

G M Bekker

Publications and source records attributed to G M Bekker.

17 recordsLinked to original sources
PubMed1983

[Changes in the nervous system in amyloidosis].

The author investigated different areas of the nervous system in five cases of primary and in seven cases of secondary amyloidosis--rheumatoid arthritis accompanied by amyloidosis. In nine out of the 12 cases studied, amyloid was found in the vascular walls and in the stroma of the peripheral, somatic and vegetative nervous system, by using light, polarization, fluorescent and electron microscopy. In cases of rheumatoid arthritis, apart from amyloid deposits, the connective tissue and vascular walls exhibited mucoid swelling, fibrinoid alterations and sclerosis, i.e., stages of the pathological process which are characteristic of this disease in particular and of collagen diseases in general.

Adult↗
PubMed1980

[Changes in the nervous system in lupus crises].

In 31 patients suffering from systemic lupus erythematosus, morphological examinations of the central and peripheral nervous system were carried out. In the nervous system, changes of the connective tissue, the vessels and the myelin membranes of the nervous fibres were discovered. Characteristic of the systemic lupus erythematosus were nuclear pathology and appearance of micronecroses in the cerebral tissue. The most pronounced changes in the nervous system were noted in 14 cases of autoimmune lupus crises. In these cases, the disease was distinguished for a high clinical and immunological activity.

Acute Disease↗
PubMed1980

[Morphological changes in the nervous system in rheumatoid arthritis].

The central and peripheral nervous systems were subjected to morphologic study in 16 patients suffering from rheumatoid arthritis. The following pathological stages characteristic for collagenous diseases were revealed in the connective tissue and vascular walls: mucoid swelling, fibrinoid changes, sclerosis and amyloidosis. The intensity of acute degenerative changes in the connective tissue of the nervous system was largely dependent on the clinical and immunologic activity of the disease.

Adult↗
PubMed1977

[Morphologic changes in the nervous system in systemic lupus eryethmatosus].

The central and peripheral nervous systems were examined morphologically in 31 cases of systemic lupus erythematosus (SLE). The lesions of the connective tissue and the vessel walls in the central nervous system are the manifestations of the generalized involvement of the entire connective tissue system in SLE. Morphologic signs relatively specific for SLE, such as fibrinoid necrosis of the connective tissue and vessels, nuclear pathology, as well as myelin changes of pulpous membrnes of nerve fibers and formation of micronecroses in the brain tissue, were observed most frequently in autoimmune crisis conditions. In these cases, a high clinical and immunological activity of the disease was observed.

Adult↗