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Biomedical subjects

G M Daniele

Publications and source records attributed to G M Daniele.

At least 19 recordsLinked to original sources

Endometriosis of the round ligament: description of a clinical case and review of the literature.

We report a case of endometriosis of the round ligament in a 29-year-old woman, who complained of a lump with a diameter of about 2.5 cm in the right inguinal region, which increased in bulk and was accompanied by intense pain during the menstrual period. The clinical suspicion of inguinal endometriosis, supported by ultrasonography and Magnetic Resonance (MR), was confirmed by histological examination of the surgical specimen, which included the mass and the extraperitoneal segment of the round ligament. The authors conclude that the appearance of a lump in the inguinal region associated with subjective and objective changes of the lesion in relation to the menstrual cycle must raise the suspicion of endometriosis among the possible diagnoses.

Adult↗

[Acute abdomen due to rupture of mesenteric cysts. Observations on a clinical case and review of the literature].

Personal experience based on a clinical case of a young woman with acute abdominal pain referable to acute appendicitis is presented. The surgical procedure was performed through a Mc Burney incision and revealed the rupture of mesenteric cysts; removal of the cysts was carried out without intestinal resection. Post-operative course was uneventful and 2 years follow-up showed no recurrence. Mesenteric cysts are an uncommon pathology, mainly in adult ages. After an analysis of the incidence and etiology, the pathological features and types of clinical presentation are discussed. Diagnosis in asymptomatic cases is usually made in search of other diseases. Complications are rare: rupture, infection and intestinal obstruction. In such cases, the clinical presentation is usually attributable to the main causes of acute abdomen, unless ultrasonography or CT scan are performed. When mesenteric cyst is diagnosed, a laparoscopic approach should be performed, even if in emergency traditional surgery is justified. Total excision of the cyst is necessary to avoid recurrence and obtain a correct pathologic evaluation.

Abdomen, Acute↗

Cellular fibrous histiocytoma of the skin: evidence of a clonal process with different karyotype from dermatofibrosarcoma.

Recently, a distinct variant of cutaneous fibrous histiocytoma (FH) has been histologically characterized as a "cellular" subtype. This variant is often mistaken for sarcoma, including dermatofibrosarcoma protuberans. We report a case of cellular FH of the skin in which the cytogenetic analysis demonstrated a novel chromosome pattern, possibly allowing distinction from its histologic simulants.

Adult↗

[Neuroendocrine carcinoma of the skin].

Merkel cell carcinoma is an unusual neuroendocrine tumour that arises in the derm. The case reported seemed to deserve the author's attention because of the clinical features, pathological findings and natural history (local recurrence, regional lymph node metachronous metastases, distant metastases). The authors believe that a differential diagnosis between Merkel cell carcinoma and other tumours located in the subcutaneous tissue is mandatory, in order to perform specific immunohistochemical and ultrastructural study.

Aged↗

[Manometric findings in esophageal achalasia].

Manometric studies represent nowadays a very useful diagnostic procedure to identify the various esophageal motility disturbances and brought an essential contribution to improve the pathologic knowledges on achalasia. The manometric experience during the past years has proved that achalasia is characterized by different evolutive steps, varying from an early and still compensate phase to an evolved stage with progressive esophageal dilatation. The manometric features are peculiar and the various stages of the disease may be easily identified, as well as it results form the study of the illustrative cases reported by the authors. The increased diagnostic possibilities have allowed an improvement in surgical management of achalasia. The best long-term results are really obtained in the cases operated on in early stages.

Esophageal Achalasia↗

[Diverticula of the esophagus. Etiopathogenetic aspects and principles of surgical treatment].

On the basis of the new knowledges recently acquired with the manometry on the esophageal physiology, the Authors first consider both etiologic and pathologic problems then emphasize the essential principles for correct surgical treatment of esophageal diverticula. With this purpose is confirmed the importance of careful and systematic preoperative study of esophageal pressure. In this way the etiologic role of functional disorders is cleared and a correct surgical treatment, particularly as regards the indication of extramucosal esophagomyotomy, can be performed. Nevertheless the diverticulectomy, performed alone or combined with myotomy, still maintains its role in the treatment of large-size diverticular pouches.

Diverticulum, Esophageal↗