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Biomedical subjects

G M Kushner

Publications and source records attributed to G M Kushner.

12 recordsLinked to original sources

A sequential approach to radiological interpretation.

A case of large glandular odontogenic cyst of the mandible is presented in which the panoramic radiograph also demonstrated a soft tissue lesion consistent with carotid aneurysm. CT confirmed the bucco-lingual extent of the mandibular lesion and the presence of a soft tissue lesion consistent with an aneurysm of the internal carotid artery. CT angiography, MR angiography and US were used to rule out a carotid artery aneurysm prior to surgery of the mandibular lesion.

Aged↗

Odontogenic carcinoma occurring in a dentigerous cyst: case report and clinical management.

This case report describes an unusual odontogenic carcinoma, which was detected during routine periodontal examination. The lesion occurred in a dentigerous cyst associated with an impacted third molar in an otherwise asymptomatic 66-year-old male patient. The impacted tooth and lesion were excised based on evidence of radiographic change and clinical findings. An unusual histopathologic presentation is reported. The treatment provided for this tumor and the management of impacted teeth is reviewed.

Aged↗

Invited review: small versus large plate fixation of mandibular fractures.

BACKGROUND AND OBJECTIVES: Since the introduction of antibiotics in the late 1940s, open reduction and internal fixation (ORIF) gradually replaced various dental splints and devices as a means of providing additional reduction and fixation of mandibular fractures. Stainless steel wire has been recently replaced by plate-and-screw fixation. When properly utilized, this method provides convalescent function without maxillomandibular fixation (MMF). The purpose of this article is to review the evolution of small versus large plate fixation of mandibular fractures. METHODS AND MATERIALS: In the context of reports in the literature and 26 years of clinical experience, the authors review the types of mandibular rigid fixation, healing of fractures, morbidity of fracture repair, indications for rigid fixation, and evolution of techniques of treatment. RESULTS AND/OR CONCLUSIONS: Although numerous devices and techniques--bone clamps, intra- and extramedullary K-wires, metallic mesh, and other means--have been used and abandoned, modern plate and screw systems, if not the standard of care, have become widely accepted and used.

Bone Plates↗

Open reduction and internal fixation of acute mandibular fractures in adults.

The mandible is often fractured during maxillofacial trauma because of its prominence within the facial skeleton and the fact that it is a favorite target in interpersonal violence. Treatment of mandibular fractures has made significant advances over the years due to the study of biomechanical principles, advancements in biomaterials and instrumentation and scientifically based research of treatment outcomes. This article will review the principles and philosophy of AO/ASIF techniques as applied to treatment of mandible fractures. Representative cases of different mandible fractures and their treatment will reinforce the clinical application of rigid fixation techniques.

Adult↗

Myositis ossificans traumatica of the masseter muscle: review of the literature and report of two additional cases.

Myositis ossificans traumatica of the masseter muscle is uncommon. The condition is benign and results in reactive heterotopic bone formation, usually producing limitation of opening of the jaws. Radiographic and microscopic examination can confirm the diagnosis. Treatment of myositis ossificans traumatica of the masseter muscle is surgical, with other modalities used when occurring in other muscles of the body.

Adolescent↗

Safety and efficacy of purified factor IX concentrate and antifibrinolytic agents for dental extractions in hemophilia B.

This study evaluated the safety and efficacy of combined treatment with epsilon-aminocaproic acid or tranexamic acid and monoclonal antibody purified factor IX (MAb factor IX) for prophylaxis against bleeding in eight hemophilia B patients undergoing nine dental extraction procedures. All patients achieved excellent hemostasis without clinical evidence of thrombosis. There were no significant changes in hemoglobin or hematocrit or in markers of hemostatic system activation (prothrombin fragment F1+2, fibrinopeptide A, and fragment B beta 15-42) after surgery. Thus, a highly purified factor IX concentrate and antifibrinolytic therapy can be effectively and safely combined in hemophilia B patients undergoing dental extractions.

Adult↗

Effects of chemotherapy in patients with dental implants.

Endosseous implant placement is generally considered to be contra-indicated in patients undergoing chemotherapy for the treatment of cancer. A case is presented where a patient was diagnosed with cancer and began chemotherapy four weeks after endosseous implants were placed. The impact of chemotherapeutic agents on endosseous implant acceptance as well as upon oral tissue is examined.

Abdominal Neoplasms↗