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Biomedical subjects

G M Laskin

Publications and source records attributed to G M Laskin.

10 recordsLinked to original sources
PubMed1994

[Prevalence of post-tuberculous changes in the bronchopulmonary system in the patients with chronic bronchitis].

The prevalence of chronic nonspecific pulmonary diseases was studied in 1880 industrial workers from Russia. The diseases were reported in 26.5% of the examinees. Fluorograms of chronic bronchitis patients indicated residual posttuberculous bronchopulmonary changes in 28.5% of the cases (p < 0.01). By form the bronchitis depended on the variety of the posttuberculous alterations: 76.4% of the asthmatic bronchitis sufferers had minor residual posttuberculous changes (petrifaction of intrathoracic lymph nodes), those with irritative bronchitis had extended posttuberculous changes in 72.7%.

Asthma↗
PubMed1989

[Status of hemodynamics and its response to exercise in patients with acute pneumonia].

The patients with croupous and focal pneumonia were examined for the response of systemic hemodynamics (HR, SV, MV, BP, PR) to bicycle ergometry in the acute disease period (after temperature normalization, before discharge from hospital and in 6 months following the clinical recovery). Appreciable disorders of the adaptation mechanisms have been demonstrated. They were especially remarkable in the patients with croupous pneumonia and persisted even after 6 months following the patients' discharged from hospital.

Acute Disease↗
PubMed1985

[Assessment of the pulmonary blood flow changes in thromboembolism of small branches of the pulmonary artery].

Patients with thromboembolism of small branches of the pulmonary artery (TESPA) were examined by rheopulmonography (RPG) for the pulmonary blood flow over the zones of thromboembolism and uninvolved parts of the lungs. The study was performed at the initial disease stage, on days 3-7 of the disease and before the patient's discharge from hospital. It was shown that pulmonary circulation undergoes some successive changes. During the first phase, the total vascular hypertension and arterial hypertension of the pulmonary circulation together with occlusion are noted. During the second phase, dilatation of the arterial bed in the healthy zones and normalization of arterial hypertension together with the reduced blood flow in the area of thromboembolism are observed. The convalescence phase is characterized by the recovery of the blood flow in the area of thromboembolism and return of the arterial tone in the pulmonary circulation to normal. RPG permits one to have an objective evaluation of the clinical picture of TESPA and therapy received by the patients.

Adult↗
PubMed1984

[Clinico-functional characteristics of idiopathic fibrosing alveolitis (Hamman-Rich syndrome)].

The clinical and functional features of idiopathic fibrosing alveolitis (IFA) were analyzed in 31 patients. In 24 patients, the diagnosis was confirmed by histological study of the pulmonary tissue obtained by means of open lung biopsy or at autopsy. Progressive dyspnea was the earliest clinical symptom of IFA. High temperature, weight loss, cyanosis and other symptoms were characteristic of an acute disease course. Crepitation was the most characteristic symptom as far as the objective data are concerned. Detailed examination of respiratory function with the use of spirography, general plethysmography, forced oscillation technique, study of the diffuse capacity of the lungs and blood gases, and other methods showed that the most characteristic functional features of pulmonary respiration in IFA involved a decrease in the static pulmonary volumes, an increase in elastic pulmonary resistance, normal patency of the large and medium bronchi, and a diminution of the diffuse capacity of the lungs during respiratory arrest, as well as that of the diffuse capacity of the alveolocapillary membrane. The data obtained indicate that today one can discuss only the most characteristic rather than the pathognomonic clinical and functional symptoms of IFA.

Adolescent↗
PubMed1979

[Role of changes in the hemodynamics of the pulmonary circulation in pulmonary gas exchange].

High pressure in the lung artery was maintained with the aid of i. v. serotonin administration (0.5 mg/ml) in dogs during 10 min. The simultaneous increase of the intravascular pressure in minor circulation and of the lung volume circulation was followed by an increasing blood volume in lungs, diffusion capacity of lungs, oxygen tension in the arterial blood, and satiation of the latter with oxygen. The combined action of the above two hemodynamic factors aids to opening of latent vascular areas, to a more regular distribution of perfusion over the lung areas according to the ventilation level. This mechanism seems to be one of the first compensatory responses to disturbances in the lung gas exchange.

Animals↗