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Biomedical subjects

G M Macaluso

Publications and source records attributed to G M Macaluso.

At least 37 records · Page 2Linked to original sources

Acute sensory and autonomic neuropathy: possible association with coxsackie B virus infection.

This report describes a 26 year old woman with a Coxsackie B virus infection complicated by an acute pandysautonomic and sensory neuropathy. Electrophysiological studies suggested an axonal neuropathy. A sural nerve biopsy performed early in the disease showed axonal degeneration with a virtual absence of unmyelinated fibres and moderate loss of myelinated fibres, mainly affecting the small fibres; this differs from previous reports. An immune-mediated or direct virus action might explain the pathogenesis of this unusual evolution of a viral infection.

Adult↗

Presurgical electrophysiological findings in acoustic nerve tumours.

The clinical involvement of the facial nerve is a rare finding among the initial symptoms of acoustic neurinomas. However, compression of the facial nerve is a common intraoperative finding. Blink reflex was recorded in 20 patients affected by cerebellar-pontine angle tumor confirmed at surgery. Recordings were also made of the M-response of the facial nerve from the naso-labial folds. In 6 cases jaw reflex was also recorded. In summary, these electrophysiological studies revealed a facial nerve damage in 13 and a trigeminal nerve dysfunction in 2 out of 18 clinically unaffected patients. The combined study of the 3 tests proved to be useful when the blink reflex showed an isolated R1 delay, that is, in cases in which the level of damage along the trigemino-facial reflex arc cannot be defined by the recording of the blink reflex alone.

Adolescent↗

[Dysgeusia in clinical practice. 2. Pathology].

The various types of dysgeusia are discussed and a clinical classification is proposed. Dysgeusia are divided according to the modifications of the intensity of the perception: ipergeusia and ipogeusie/ageusia. The latter are the most frequent and important ones; they are divided in congenital ones, rapidly developing ones, and slow developing ones. A practical way to distinguish among the rapidly arousing ones is to consider the duration of the symptom. If it lasts more than a week the probabilities of an underlying serious illness grow, mainly of CNS. The slow onset ones are most commonly due to general metabolic alterations, among which diabetes, and to common habits, like smoking.

Aging↗

[Functional velopalatal insufficiency. Therapeutic possibilities].

The function of the soft palate is complex; it takes part in speech, swallowing, and masticatory mechanisms. Its pathology ranges from morphological deficits to functional ones; these are commonly due to a central nervous system damage. The clinical analysis is based upon examination and instrumental prove, and leads to an optimum choice between surgical and prosthetic solutions. The latter is the best one in terms of quick execution, low costs and future possibilities of improvement.

Adult↗

[Dysgeusia in clinical practice. 1. Physiology].

The anatomical basis of taste are discussed both in their peripheral and in central aspects. The perception is based upon four principal flavors; this happens by complex chemical interactions between peripheral receptors of papillae and the taste producing substances. The nervous stimulus flows through fibres of VII-IX-X cranial nerves up to the tractus solitarius nucleus; successive elaboration leads to the taste sensation, whose principal cortical site is the zone between Silvius and Rolando's sulcus. The distribution of the sensible zones for the fundamental flavors is presented.

Dysgeusia↗

Magnetic motor evoked potentials (MEPs) in masseter muscles.

Electromyographic responses of the masseter muscles and orbicularis oris muscles following transcranial magnetic stimulations were recorded with surface and needle electrodes. MEPs in masseter muscles (latency 6.9 +/- 0.71 ms, mean +/- SD) due to activation of controlateral cortico-nuclear connections were evoked by magnetic stimulations at 4 cm laterally to the vertex on the biauricular line. These MEPs were followed bilaterally by a silent period lasting about 20 ms and, less constantly, by a later silent period lasting up to 80 ms. The ipsilateral responses to the same stimuli presented shorter latencies and higher amplitudes and they were ascribed to direct stimulation of the trigeminal nerve, probably its intracisternal portion. Ipsilateral masseter "cortical" MEPs could be elicited only by a lower output setting (70% of the maximum output) of the stimulator. Orbicularis oris MEPs were polyphasic and dispersed with latencies ranging from 7 to 11 ms. In patients with hemispheric or capsular ischemic lesions "cortical" MEPs were absent when stimulating the affected hemisphere and present when stimulating the unaffected one. We suggest that the direct corticomotoneuronal projections for the masseter are mainly crossed.

Adult↗

Motor-evoked potentials in masseter muscle by electrical and magnetic stimulation in intact alert man.

The electromyographic responses of the masseter after different types of transcranial stimulation were recorded with surface and needle electrodes. Magnetic stimulation at 4 cm lateral to the vertex on the biauricular line elicited MEPs in the contralateral masseter (latency 6.9 ms) due to activation of motor cortex or adjacent elements along the cortico-nuclear pathway. The ipsilateral responses to the same stimuli and to more lateral ones had shorter latencies and were ascribed to direct stimulation of the trigeminal nerve, probably its intracisternal portion. This was also the probable origin of the ipsilateral MEPs after both anodic and cathodic bipolar electrical stimulation at 7 and 11 cm lateral to the vertex on the biauricular line.

Adult↗

[Individual cast posts for single anterior implants].

The Authors utilized in order to replace anterior missing teeth osseointegrated implants provided with individual angled posts. These types of abutment are used to allow a good parallel situation between implants with different angulation and also between implants and proximal teeth. The head of this abutment is thread to receive the screw that allows the crown to be fastened.

Alveolar Bone Loss↗

[Headaches and craniofacial pains with dental involvement in the classification of the International Headache Society (1988)].

Facial pain often presents complex diagnosis, requiring other specialists' consultation. The use of different terminology and protocols can affect the information exchange negatively. These problems in the field of headache, cranial neuralgias and facial pain lead the International Headache Society to introduce a new classification in 1988. The chief difference with the previous ones is the presence of strictly codified diagnostic principles. Its target is research, but it can help the general practice as well. We discuss the most interesting points to the stomatologist.

Facial Pain↗

[Masseteric responses following electrical stimulation of the scalp].

Electromyographic responses of the masseter muscles following electric transcranial stimulations by a conventional constant current stimulator were recorded with surface and needle electrodes. Ipsilateral motor evoked responses following both anodic and cathodic bipolar electrical stimulations performed at 7 and 11 cm laterally to the vertex on the biauricular line were recorded, with latencies ranging from 2 to 3.6 ms. Contralateral responses were not elicited. The ipsilateral responses to stimuli were ascribed to direct stimulation of the trigeminal nerve, probably its intracisternal portion.

Adult↗

[Magnetic stimulation of the scalp: the responses of the masseter muscles. I].

Magnetic stimulation of nervous elements is a new neurophysiological technique. It easily succeeds in stimulating the brain motor cortex. We applied this technique to the trigeminal motor system, recording responses in masseter muscles. The magnetic stimulations at 4 cm laterally to the vertex on the biauricular line elicited responses in the contralateral masseter due to activation of motor cortex or adjacent elements along the cortico-nuclear pathway. The ipsilateral responses to the same stimuli and to more lateral ones presented shorter latencies and they were ascribed to direct stimulation of the trigeminal nerve, probably its intracisternal portion. The latency values were 6.9 +/- 0.71 ms and 3.6 +/- 0.3 ms respectively.

Adult↗

[Magnetic stimulation of the scalp: the responses of the masseter muscles. II].

Magnetic stimulation of nervous elements is a new technique of investigation in intact alert man. Electromyographic responses of the masseter muscles were recorded in normal volunteers and in two patients with hemispheric or capsular lesions, both by surface and needle electrodes. In the patients "cortical" responses were absent when stimulating the affected hemisphere and present when stimulating the unaffected one. These findings suggest that the direct facilitating cortico-nuclear projections for the masseter muscle are mainly crossed. Nevertheless the presence of clear ipsilateral responses after stimulation of the unaffected hemisphere demonstrates the existence of uncrossed projections; in fact only the ipsilateral motor cortex can be the site of origin of the responses in these patients.

Adult↗

[Clinico-diagnostic evaluation of craniomandibular disorders].

Diagnostic setting of patients with craniomandibular disorders, imposes a careful valuation of the single components of the stomatognathic system (articular, occlusal, neuromuscular) to identify the etiologic factors which have led to the pathology. The Authors illustrate a clinic standardized procedure evaluating the different aspects and punctualizing the importance of the anamnestic investigation to define the psycho-emotional component of the patient. Only a careful clinic valuation permits a therapeutic programme to obtain a stable result without any relapse.

Auscultation↗

[Histopathological evaluations in dental caries: preliminary data].

The intent of this research is to describe the histopathological evolution of the carious lesion on the teeth with great crown caries. The histo-pathological study of the dental structure affected by carious lesion can favour a better uptake of some pathological and semeiotic events to whom often the clinician don't get to give an exact explanation.

Adult↗