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Biomedical subjects

G M Raghoebar

Publications and source records attributed to G M Raghoebar.

At least 19 recordsLinked to original sources
PubMed2003

Ultrasound stimulation of maxillofacial bone healing.

A substantial part of the maxillofacial surgery practice deals with maxillofacial bone healing. In the past decades, low-intensity ultrasound treatment has been shown to reduce the healing time of fresh fractures of the extremities up to 38%, and to heal delayed and non-unions up to 90% and 83%, respectively. Based on the assumption that the process of bone healing in the bones of the extremities and maxillofacial skeleton is essentially the same, the potential of ultrasound to stimulate maxillofacial bone healing was investigated. Although limited evidence is available to support the susceptibility of maxillofacial bone to the ultrasound signal, ultrasound may be of value in the treatment of delayed unions, in callus maturation after distraction, and in the treatment of osteoradionecrosis.

Animals↗
PubMed2002

Five years of aftercare of implant-retained mandibular overdentures and conventional dentures.

The purpose of this multicentre randomized clinical trial was to analyse surgical and prosthetic aftercare and clinical implant performance of edentulous patients with implant-retained mandibular overdentures and of patients with conventional dentures, either or not after pre-prosthetic vestibuloplasty and deepening of the floor of the mouth. The evaluation period was 5 years. The implant systems evaluated were the IMZ implant system, the Brånemark implant system and the Transmandibular Implant system. The centre in Groningen had five groups (n=149) and the centre in Nijmegen had three groups (n=86). The evaluation comprised of surgical and prosthetic aftercare, together with clinical implant performance (CIP). The highest implant loss (29%) is found in the Transmandibular Implant group. All groups had prosthetic revisions and complications according to the CIP-scale. The majority of the patients in the endosseous implant groups were subject to minor complications. The CIP-score of the Transmandibular Implant group is significantly higher than the scores of the other groups, because of the high number of lost posts. In 26;1% of the patients in this group score 4 is given, which means failure of the implant system. From this study it can be concluded that the endosseous implant systems used in this study have less surgical aftercare and a better clinical implant performance than the Transmandibular Implant system and are therefore the systems of choice for the edentulous mandible.

Aftercare↗
PubMed2002

[Implant-retained overdentures compared with complete dentures with or without preprosthetic surgery. Satisfaction and subjective chewing capabilities].

The aim of this prospective randomized clinical trial was to evaluate and compare a set of clinical items and satisfaction of a group of edentulous patients during a 5-year follow-up. They were treated according to one of the following modalities: 61 patients with a mandibular overdenture on two implants (IMP-group), 60 patients with a conventional complete denture (VP-group) and 28 patients with a complete denture after preprosthetic surgery (MVP-group). It can be concluded that endosseous implants, serving as retention for a mandibular overdenture, have a high survival rate after 5 years of follow-up (93%). The mean satisfaction score of the VP-group was lower than of the IMP-group. The mean satisfaction score of the MVP-group is lower than of the IMP-group.

Dental Implantation, Endosseous↗
PubMed2001

Treatment outcome of bone-anchored craniofacial prostheses after tumor surgery.

BACKGROUND: Percutaneous endosseous implants have acquired an important place in the prosthetic rehabilitation of patients with craniofacial defects. The objective of this study was to evaluate the clinical outcome of the use of endosseous implants in the orbital and auricular region as well as to assess the satisfaction of patients with implant-retained craniofacial prostheses after tumor surgery. METHODS: The clinical outcome and patient satisfaction of implant-retained prostheses in the auricular and orbital region were evaluated in a group of 26 patients with facial defects after tumor surgery by using standardized questionnaires and a clinical assessment. Twelve patients (n = 31 implants) received the implants during ablative tumor surgery, from which 7 patients (n = 20 implants) were treated with radiation therapy after surgery (mean, 65 grays [Gy]). Fourteen patients (n = 44 implants) received the implants after the tumor surgery, from which 5 patients (n = 21 implants) were irradiated after ablative surgery (mean, 54.4 Gy), but before implant placement. RESULTS: No implants were lost in patients who had not undergone irradiation (100%), whereas 5 implants were lost in the irradiated group (87.8%). The overall implant survival rate was 93.3%. The peri-implant tissues had a healthy appearance, and no cases of osteoradionecrosis occurred. When compared with patients treated with conventional adhesive retained facial prostheses, satisfaction was higher in patients treated with implant-retained facial prostheses. CONCLUSIONS: From this study, it is concluded that implant-retained facial prostheses are better tolerated than adhesive retained prostheses and offer an improvement in the quality of life. Radiotherapy is not a contraindication for the use of osseointegrated implants in the maxillofacial region, but the loss of implants is higher than in nonirradiated sites.

Adult↗
PubMed2001

Maxillary bone grafting for insertion of endosseous implants: results after 12-124 months.

Insertion of endosseous implants in the atrophic maxilla is often complicated because of lack of supporting bone. Augmentation of the floor of the maxillary sinus with autogenous bone graft has been proven to be a reliable treatment modality, at least in the short term. The long-term clinical and radiographic outcome with regard to the grafts, the implants and satisfaction of the patients with their implant-supported overdenture was studied in 99 patients. The sinus floor was augmented with bone grafts derived from the iliac crest (83 subjects, 162 sinuses, 353 implants), the mandibular symphysis (14, 18, 37), or the maxillary tuberosity (2, 2, 2). Before implant installation, the width and height of the alveolar crest were increased in a first stage procedure in 74 patients, while in the other 25 patients augmentation and implant installation could be performed simultaneously (width and height of the alveolar crest >5 mm). Perforation of the sinus membrane occurred in 47 cases, which did not predispose to the development of sinusitis. Loss of bone particles and sequestration were observed in one (diabetic) patient only, in whom a dehiscence of the oral mucosa occurred. A second augmentation procedure was successful in this patient. Symptoms of transient sinusitis were observed in 3 patients. These symptoms were successfully treated with decongestants and antibiotics. 2 other patients developed a purulent sinusitis which resolved after a nasal antrostomy. In all cases, the bone volume was sufficient for implant insertion. 32 of 392 inserted Brånemark implants (8.2%) were lost during the follow-up. After the healing period of the bone grafts, no sinus pathology was observed. The patients received implant-supported overdentures (72 patients) or fixed bridges (27 patients). Overall, the patients were very satisfied with the prosthetic construction. We conclude that bone grafting of the floor of the maxillary sinus floor with autogenous bone for the insertion of implants is a reliable treatment modality with good long-term results.

Adolescent↗
PubMed2001

Morbidity of chin bone harvesting.

The chin is a very common donor site for autogenous bone grafts. The aim of this retrospective study was to evaluate long-term morbidity of the donor site following chin bone graft harvesting. One to three years after grafting of local bone defects of the anterior maxilla with chin bone, 21 patients were recalled for objective assessment of any residual morbidity at the harvesting area. Morbidity as well as satisfaction of the patients were evaluated by a survey of the medical record, a mail-in questionnaire, and a standardized physical examination. The outcome of this study showed that there was good acceptance of the chin bone harvesting procedure. The objective morbidity was low, but subjectively almost half of the patients reported a changed (decreased) sensibility in the harvesting area. This subjective change in sensibility did not result in noteworthy complaints or discomfort by the patients, however. Although bone harvesting from the chin is generally considered as a good option for reconstruction of local bony defects, the patients should be informed about the potential hazard of a changed sensibility in the chin region.

Adolescent↗
PubMed2001

Implant-retained mandibular overdentures: 6-year results of a multicenter clinical trial on 3 different implant systems.

PURPOSE: The goal of this multicenter prospective clinical trial was to compare clinical outcome and post-treatment care and patient satisfaction with different implant systems used for mandibular overdenture treatment during a 6-year follow-up period. PATIENTS AND METHODS: A total of 87 edentulous patients with a severely resorbed mandible (bone height, 8 to 15 mm) received treatment involving either 2 Intra Mobiele Zylinder implants (IMZ group, n = 41) (Friedrichsfeld AG, Mannheim, Germany), 2 Brånemark implants (Brå group, n = 17) (Nobel Biocare AB, Gothenburg, Sweden) or a Transmandibular Implant (TMI; Krijnen Medical, Beesd, The Netherlands) (TMI group, n = 29). The evaluation involved clinical parameters, radiographs, surgical and prosthetic post-treatment care, clinical implant performance (CIP scale), and patient satisfaction. RESULTS: After 6 years, there was a significant difference in the mean plaque index:the mean plaque index of the TMI group was significantly higher than that of the IMZ and Brå groups. Other clinical parameters showed no significant differences. The implant survival rate of 97.5% was noted in the IMZ group, 97.1% in the Brå group, and 72.0% in the TMI group. The CIP scale were significantly worse for the TMI group. CONCLUSION: It was concluded that the IMZ and the Brånemark implant systems have a better survival rate and clinical implant performance than the TMI system. Based on these data, these systems should be the choice for the edentulous mandible with a height between 8 and 15 mm.

Alveolar Bone Loss↗
PubMed2001

[Vesiculobullous lesions of the oral mucosa].

In general practice, the dentist can be confronted with a vesiculobullous lesion of the oral mucosa. In many cases the lesion can be classified as recurrent herpes labialis, but many other causes can induce a vesiculobullous lesion of the oral mucosa and perioral skin as well. This article gives an overview of the various vesiculous and bullous lesions of the oral mucous membranes. Special attention is given to the possible causes and their treatment.

Blister↗
PubMed2000

Use of short endosseous implants and an overdenture in the extremely resorbed mandible: a five-year retrospective study.

PURPOSE: A retrospective study was performed to assess the success of short endosseous implants in combination with an implant-retained overdenture in the extremely resorbed mandible. PATIENTS AND METHODS: Patients included had a mandible not exceeding a median height of 12 mm measured on a standardized lateral cephalometric radiograph. Seventeen patients (14 women, 3 men; mean age, 65 years) with 68 endosseous implants were clinically and radiographically evaluated. RESULTS: During the follow-up period (mean, 77 months; range, 60 to 97 months), 8 implants were lost, bringing the cumulative survival rate to 88%. The peri-implant tissues were in good condition, and the bone loss around the implants was minimal. CONCLUSION: Because of the relative simplicity and low morbidity of this treatment strategy, it is a justified treatment option.

Aged↗
PubMed2000

The oblique radiographic technique for bone height measurements on edentulous mandibles: a preclinical study and an introduction to the clinical use.

OBJECTIVE: The aim of this study was to quantify the effect of mandibular angulation, position, and shape of the edentulous mandible on the distortion of its image on lateral oblique radiographs in a preclinical study. Suggestions for the clinical use of this technique are made. STUDY DESIGN: Five edentulous dry mandibles were used, varying in size from small to wide and equipped with metal bars in and on top of the mandible. The mandibles were radiographed at 9 different positions by tilting the mandible around the intercondylar axis and by using the oblique projection technique in a cephalostat. RESULTS: The length of the images of the metal bars varied significantly when we tilted the mandibles from 20 degrees to -20 degrees. As a result of the effects of magnification and distortion, the image size varied from between 0.96% and 1.06% of the real size. Neither the size of the mandible nor the position of the bars was related to the degree of magnification. CONCLUSION: The oblique projection technique has limited geometric errors in depicting the edentulous mandible. For evaluative bone height measurements in patients with extremely resorbed mandibles treated with dental implants, it is a promising technique if the patient (specifically the mandible) can be positioned reproducibly in the apparatus.

Analysis of Variance↗
PubMed2000

Horizontal osteotomy for reconstruction of the narrow edentulous mandible.

The aim of this retrospective study was to evaluate the applicability of a horizontal osteotomy procedure for reconstruction of a narrow edentulous mandible in order to enable insertion of implants. In 7 edentulous patients a narrow inferior alveolar ridge was reconstructed with autogenous bone grafts harvested by a horizontal osteotomy procedure (mean width of the top of the alveolar crest before grafting 1.3 +/- 0.3 mm, after grafting 5.6 +/- 0.6 mm). Insertion of endosseous implants (10 Brånemark implants, 8 ITI Bonefit implants) was performed 3 months after the grafting procedure. Implant supported overdentures were fabricated 3 months after implantation. At regular time intervals a standardized clinical and a radiographic evaluation was performed. All grafted sites showed sufficient bone volume for insertion of the implants at the moment of implantation. At time of evaluation (mean 37 +/- 14.6 months, range 14-68 months) all implants and overdentures functioned well. None of the patients showed a disturbed sensitivity of the lip or chin region. It is concluded that reconstruction of a narrow edentulous mandible with autogenous bone grafts harvested by an intraoral horizontal osteotomy was shown to be a reliable preimplantology procedure with potential applicability in this group of patients.

Adult↗
PubMed2000

Effectiveness of three treatment modalities for the edentulous mandible. A five-year randomized clinical trial.

Currently, 3 treatment options are available for patients with denture complaints and an edentulous mandible with a height of at least 15 mm: meticulous construction of a new set of dentures (CD), construction of a new set of dentures following preprosthetic surgery to enlarge the denture-bearing area (PPS), and construction of an implant-retained mandibular overdenture (IRO). The aim of this study was to evaluate patient satisfaction and subjective chewing ability of edentulous patients treated with one of these treatment modalities. Ninety edentulous patients (Cawood class IV and V, mean mandibular height 20.7 mm) were randomly assigned to receive 1 of these 3 groups. Denture satisfaction and chewing ability were assessed using questionnaires focusing on denture-related complaints and problems chewing different types of food were assessed before treatment, and 1- and 5-years after treatment. At the 1-year evaluation, significantly better scores were observed in the 2 surgical groups (IRO, PPS) than in the CD group. At 5-year evaluation the "complaints of the lower denture" showed a significantly better score in the IRO group when compared to the PPS and CD groups. No significant differences were observed between the PPS and CD group. From this study it is concluded that both in the short and long term denture satisfaction appears most favourable in the IRO group when compared to the PPS and CD groups. Implant-retained overdentures are therefore a satisfactory treatment modality for edentulous patients with problems with their lower denture, even in cases of not severely resorbed mandibles.

Analysis of Variance↗
PubMed2000

A controlled clinical trial of implant-retained mandibular overdentures; five-years' results of clinical aspects and aftercare of IMZ implants and Brånemark implants.

The aim of this prospective randomized controlled clinical trial was to evaluate a set of clinical items and prosthetic aftercare of edentulous patients with a mandibular overdenture retained by 2 IMZ implants or 2 Brånemark implants during a 5-years' period. Patients were allocated to the IMZ group (n = 29) or the Brånemark group (n = 32) by a computerized balancing method. In the IMZ group 4 implants were lost during the 5-years' follow-up (survival rate: 93%). In the Brånemark group 9 implants were lost (survival rate: 86%). All patients were re-operated successfully. Multiple prosthetic revisions were necessary in both groups, especially the precision attachment system in the overdenture was subject to frequent fracture or loosening. From this study can be concluded that there is no difference in clinical state, radiographical state, survival rate and clinical implant performance between the IMZ implant system and the Brånemark implant system supporting an overdenture on 2 implants after 5 years of follow-up.

Chi-Square Distribution↗
PubMed2000

A comparison of labial and crestal incisions for the 1-stage placement of IMZ implants: a pilot study.

PURPOSE: The aim of this study was to compare the crestal incision with the labial flap design when inserting a 2-stage implant system in a nonsubmerged manner. PATIENTS AND METHODS: Ten consecutive edentulous patients with a severely resorbed mandible (Cawood Class V to VI) that resulted in reduced stability and insufficient retention of the lower denture were included. In all patients, 2 IMZ implants were inserted in a 1-stage procedure in the mandibular canine regions as part of an implant overdenture treatment. In 5 patients, the labial flap approach was used, and a crestal incision approach was used in the other 5 patients. Standardized evaluations were performed at 2, 6, and 12 weeks after implant placement and 12 months after placement of the new prosthesis. RESULTS: In the first postoperative weeks, more hyperplasia occurred around the implants inserted by the crestal incision than the labial flap. However, after 1 year of function, no striking differences between the 2 groups were present with regard to the clinical and radiographic parameters. CONCLUSIONS: From this pilot study, it was concluded that both the crestal incision and the labial flap approach are reliable procedures for insertion of IMZ implants in a 1-stage procedure. However, because of the smaller risk of soft tissue overgrowth, there is a preference for the labial flap approach.

Adult↗
PubMed2000

Etiology and management of mandibular fractures associated with endosteal implants in the atrophic mandible.

Mandibular fractures can occur with the insertion of endosseous implants. Four patients whose mandibles were fractured with the removal or insertion of mandibular endosseous implants are described. Three of the patients required an autogenous bone graft to repair the fracture, and 1 patient was managed with a reconstruction plate. Strategies for prevention and treatment of this uncommon complication are discussed.

Aged↗