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Biomedical subjects

G M Rao

Publications and source records attributed to G M Rao.

At least 37 records · Page 2Linked to original sources
PubMed1986

Correlation between serum alkaline phosphatase activity and blood glucose levels.

Fasting blood glucose levels and serum alkaline phosphatase activity of age-matched Libyan diabetic men (168) and women (168) were determined. The mean levels of blood glucose of men and women were 227 +/- 6 and 237 +/- 5 mg/dl, respectively. The respective values of serum alkaline phosphatase were 179 +/- 5 and 199 +/- 6 IU/l. The mean serum phosphatase activity of women was significantly higher (p less than 0.001) than that of their male counterparts. A statistically significant positive correlation was found between serum alkaline phosphatase and blood glucose levels of these diabetic patients (r = 0.35; p less than 0.001).

Adult↗
PubMed1986

Effect of obesity on erythrocyte count and hemoglobin levels in Libyan diabetic patients.

Fasting blood glucose, erythrocyte count and hemoglobin levels of obese and nonobese Libyan diabetic women were determined. The mean values of fasting blood glucose, erythrocyte count and hemoglobin of obese diabetic women were 209.55 +/- 8.85 mg/dl, 4.986 +/- 0.04 X 10(6)/mm3 and 14.51 +/- 0.18 g/dl. The respective values for nonobese diabetic women were 243.47 +/- 12.56 mg/dl, 4.865 +/- 0.06 X 10(6)/mm3 and 14.31 +/- 0.19 g/dl. The mean values of the three variables of obese patients were significantly different from those of the nonobese patients. Statistically significant correlations were found between fasting blood glucose levels and erythrocyte count, and hemoglobin levels in both obese and nonobese patients. The levels of erythrocyte count and hemoglobin of obese patients were higher than those of their nonobese counterparts. This elevation was attributed to the effect of obesity. It is suggested that regulation of body weight should be considered an essential step in the management of diabetes.

Blood Glucose↗
PubMed1986

Glycosylated haemoglobin and blood glucose levels in Libyan diabetic patients.

Glycosylated haemoglobin (HbA1) and fasting blood glucose levels of 178 Libyan diabetic men were determined. The mean levels respectively were 11.5 +/- 0.4% and 236 +/- 7 mg.dl-1. In this study group, there were 78 patients with insulin-dependent diabetes and 100 with non-insulin-dependent diabetes. The highest percentage of patients belong to the age group 51-60 with the onset of diabetes between 41 and 50 years of age. The highest number of obese patients were in the age group 51-60 indicating the strong association between diabetes and obesity. A statistically significant correlation was found between fasting blood glucose levels and HbA1 concentrations (r = 0.37; P less than 0.001). Correlations between urinary glucose and HbA1 or fasting blood glucose were highly significant. These diabetic patients have a poorly controlled diabetes as indicated by the correlation between HbA1 and duration of diabetes. There was no significant difference in HbA1 levels of patients undergoing insulin administration and those taking oral hypoglycaemic drugs. Glycosylated haemoglobin levels will be a valuable adjunct to blood glucose determinations in epidemiological studies.

Adult↗
PubMed1985

Negative correlation between erythrocyte count and mean corpuscular volume or mean corpuscular haemoglobin in diabetic and non-diabetic subjects.

Negative correlation was observed between erythrocyte count (RBC) and mean corpuscular volume (MCV) or mean corpuscular haemoglobin (MCH) in both sexes of diabetic and non-diabetic Libyans. The slopes of regression lines for MCV-RBC and MCH-RBC of diabetic patients were significantly lower (P less than 0.001) than those of their non-diabetic counterparts. Positive correlation was found between MCH and MCV. The slope of the regression line for MCH-MCV of diabetic patients was not significantly different from that of non-diabetic subjects.

Adult↗
PubMed1984

Erythrocyte count and hemoglobin levels in diabetic women.

Fasting blood glucose, erythrocyte counts hemoglobin levels of 131 Libyan diabetic women of Tripoli , Libya were determined. The respective mean values were 223 +/- 7 mg X dl-1, 4.97 +/- 0.034 X 10(6) X mm-3 and 14.4 +/- 0.127 g X dl-1. Sixty-five percent of these diabetic women were obese. The highest percent of diabetics belong to the age group 46-55 years. The increase in prevalence of diabetes correlates with an increase in obesity. A significant positive correlation was found between body surface area and fasting blood glucose levels (r = 0.65; P less than 0.001). Elevated levels of erythrocyte count and hemoglobin were present in these diabetic patients. Significant correlations were found between body surface area and erythrocyte count, as well as between fasting blood glucose levels and erythrocyte count, indicating the effect of obesity and diabetes on erythrocyte numbers. A significant correlation was found between fasting blood glucose levels and hemoglobin (r = 0.35; P less than 0.001). The elevated levels of hemoglobin present in these patients may be the result of haemoconcentration due to polyuria, which is always present in poorly controlled diabetic patients. The results suggest a close relationship between diabetes and obesity. Regulation of body weight/surface area is an important factor in the control of diabetes. The elevated levels of erythrocyte count and hemoglobin reflect poor control of blood glucose levels in these diabetic patients.

Adolescent↗
PubMed1984

Relationship of obesity to diabetes.

In a representative sample of 201 diabetic patients of Tripoli, Libya, 138 were obese. The highest percent of diabetics and obese belong to the age group 41-50 years. In all age groups, there was a parallel increase/decrease in obesity with diabetes. Regulation of body weight should be considered very important in control of diabetes.

Adolescent↗
PubMed1983

Serum cholesterol levels in diabetes.

Serum cholesterol levels of 474 Libyan diabetics were determined. The mean levels of diabetic men and women were 236.04 +/- 3.16 and 248 +/- 2.85 mg/100 ml, respectively. A significant correlation was found between serum cholesterol levels and fasting blood glucose in short-term diabetics. A similar correlation was observed in these diabetics between serum cholesterol levels and total body weight. However, in long-term diabetics with disease for more than a year, no such correlations were present.

Aging↗
PubMed1981

Studies on the metabolic differentiation of claw, leg and heart muscles of the fresh water field crab (Paratelphusa hydrodromus/Herbst/) 1.

The heart muscle is characterized by a high glycogen, lactic acid, lipid and fatty acids content and by high activities of phosphorylase , LDH, SDH, and GDH as an adaptation to its dynamic action of constantly pumping blood. The leg muscles behave as "fast muscles" and are characterized by having high myofibrillar. ATPase activity and relatively high activities of LDH, SDH and GDH as compared to the claw muscle which may explain their repetitive action during walking. The claw muscle is adapted to a tonic function as revealed by its low myofibrillar ATPase activity, high glycogen, high lipid and low values of LDH, SDH and GDH which further support its tonic action of short duration.

Adenosine Triphosphatases↗
PubMed1981

Effect of genetic diabetes on beta-N-acetylglucosaminidase activity in plasma, conjunctiva, muscle and kidney cortex of mice.

The activity of beta-N-acetylglucosaminidase, a lysosomal enzyme concerned with the degradation of glycoproteins and mucopolysaccharides, in plasma, conjunctiva, thigh muscle and kidney cortex of normal Swiss Albino and genetically diabetic KK mice of 20, 40, 70, 180 and 360 days of age was determined. The enzyme activity was significantly lower in the tissues of the KK mice of 180 and/or 360 days of age when compared with age-matched Swiss Albino mice. This lower enzyme activity was considered to be a reflection of the changes in the glycoprotein and basement membrane metabolism of these tissues.

Acetylglucosaminidase↗
PubMed1980

Position-related false-positive renal imaging.

A case report of false-positive renal imaging due to anterior displacement of the upper pole of the left kidney with the patient in the prone position is presented. False imaging can be avoided by imaging the kidneys with the patient in the supine position and with the detector behind the patient.

False Positive Reactions↗