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Biomedical subjects

G M Schwartze

Publications and source records attributed to G M Schwartze.

6 recordsLinked to original sources

Magnetic resonance imaging and complex partial seizures.

Magnetic resonance imaging (MRI) is a new imaging modality with potential usefulness in the evaluation of patients with seizure disorders. We studied 100 consecutive patients with complex partial seizures comparing computerized cranial tomography (CCT) with MRI. Our study revealed 36 patients with CCT abnormalities. Of these, 30 (83%) had focal abnormalities. MRI demonstrated 45 patients with abnormalities, 34 (76%) were focal. Intracranial calcifications were not visualized by MRI, but were easily demonstrated by CCT. MRI was more sensitive in visualizing cerebral atrophy, abnormal cerebral vasculature, and lesions in the posterior fossa and suprasellar region. Most importantly, several patients who had normal CCTs had abnormal MRIs consistent with neoplastic lesions. As MRI becomes more available, this imaging modality along with EEG, should be the studies of choice in evaluating patients with partial epilepsy.

Adolescent↗

Monocular elevation paresis caused by an ipsilateral lesion.

A 52-year-old woman presented with a paresis of elevation of the right eye, equally severe in abduction and adduction (monocular elevation paresis). CT demonstrated a small, right-sided tumor of the mesodiencephalic junction. Monocular elevation paresis has been attributed to lesions of the contralateral pretectum, although proof has been lacking. Now, with documentation of an ipsilateral brainstem etiology, we can postulate a lesion affecting the upgaze efferents from the ipsilateral rostral interstitial nucleus of the medial longitudinal fasciculus.

Brain Neoplasms↗

Internal ophthalmoplegia resulting from acute orbital phycomycosis.

Phycomycosis is an opportunistic infection occurring in immunocompromised hosts. It is the most acutely fatal fungal disease known. Therefore, early recognition and treatment are essential. Ocular and orbital involvement is part of a rhino-orbital-cerebral form of the disease. The orbital apex syndrome is the hallmark orbital involvement. A case of phycomycosis with internal ophthalmoplegia alone is reported. The internal ophthalmoplegia is probably secondary to involvement at the apex of the orbit, although not sufficiently diffuse to result in the complete orbital apex syndrome.

Adult↗

Opsoclonus. Update on clinical and pathologic associations.

Opsoclonus is a bizarre oculomotor disturbance consisting of rapid, involuntary, repetitive conjugate eye movements in all directions. Clinically, it has been associated with infections, neoplasms, toxins, and drugs. Pathologically, there is no apparent consistently defined structural lesion. A case of opsoclonus with postmortem results is reported. Opsoclonus in adults and available autopsy data are reviewed.

Aged↗

Convergence spasm--treatment by amytal interview. A case report.

Convergence spasm is manifest by intermittent occurrence of ocular convergence, accommodative spasm, and miosis. It is usually due to hysteria but can have an organic basis. Treatment has included various ophthalmologic interventions. An amytal interview was used successfully to establish a nonorganic basis for the gaze palsy and, more importantly, concomitant narcosuggestion proved to be effective treatment.

Accommodation, Ocular↗