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Biomedical subjects

G Mähr

Publications and source records attributed to G Mähr.

At least 19 recordsLinked to original sources
PubMed1990

[Ophthalmological significance of stenosing carotid processes].

In a retrospective study we looked at the incidence of carotid artery stenosis in 191 ophthalmological patients, which underwent duplex sonography. In all these patients the oculist had considered carotid artery stenosis to be a possible reason for the present eye disease or visual disturbance. The incidence of stenosis found in these patients was compared to a group of 186 persons of the same mean age, which underwent routine-sonography without suffering from any symptoms related to carotid artery disease. Patients with amaurosis fugax, with occluded retinal veins and patients with glaucoma associated changes of the retina (in spite of normal eye pressure) suffered more often from carotis stenosis than asymptomatic persons (statistically significant), patients with occluded retinal arteries showed also more often carotid artery stenosis than the asymptomatic collective but without statistical significance. We conclude, that patients presenting with the mentioned symptoms should undergo carotid artery sonography. Furthermore these results could be of importance in evaluation the indication for carotid thrombendarterectomy (stadium II of cerebrovascular insufficiency).

Adult↗
PubMed1988

[Characteristics of insulin and glucose regulation in short-term physical exertion and recovery in type I diabetic patients].

It is a recognized fact that diabetics stand greater risk of developing diseases of the heart and circulation system. Active sport participation, however, can reduce this risk and is therefore of particular importance for diabetics. In order to give the juvenile type diabetics the best possible advice on a 15 minute physical training program, we examined 6 insulin-dependent diabetics and compared their insulin and glucose regulation during physical activity and recovery with that of 6 healthy hobby-sportsmen of the same age. During the phase of recovery a highly significant difference in the blood sugar levels was observed (p less than 0.01). Whereas the blood sugar levels of the healthy group increased quickly in the first 5 minutes immediately following the course of activity, it was seen to decrease during the phase of recovery in 4 diabetics and 2 diabetics showed mostly a very slight increase. The insulin levels of the healthy group remained constant both during activity and recovery. Widely differing, but nevertheless constant values were also shown in the diabetics insulin levels during the course of activity. In the recovery phase however divergent courses were observed. The insulin levels of 4 diabetics increased and of the other 2 they decreased slightly. Juvenile type diabetics therefore show no special characteristics compared to their healthy counterparts during a 15 minute physical activity. In the recovery phase however their blood glucose increase reaction is lacking. This reaction is in fact impeded by the slight increase of the insulin level. Thus, juvenile type diabetics are potentially prone to hypoglycemia immediately following physical activity.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗
PubMed1985

[Amylase and lipase as reference values for the differential diagnosis of chronic kidney failure and pancreatitis].

To differentiate between pancreatitis in patients with chronic renal insufficiency and uremic pancreopathy we investigated 23 patients with chronic renal insufficiency, 28 patients on hemodialysis before and after treatment and 13 patients after renal transplantation. As controls served 15 healthy people. The total amylase in serum is significantly elevated in patients with chronic renal insufficiency regardless if they were treated with hemodialysis or not. This elevation is due to an elevation of the pancreatic isoenzyme. The testing of both isoamylases (pancreatic and salivary) does not contribute to a better diagnosis. Patients with chronic renal insufficiency show a lower concentration of the amylases in their urine than their healthy controls. Lipase and creatinin show a linear correlation in serum. In the individual case it is not possible to draw a definite diagnostic conclusion using the above mentioned parameters because of the wide distribution of the measured values.

Amylases↗
PubMed1983

[Iatrogenic diseases of the hematopoietic system in the aged].

As far as iatrogenic damage to haematopoesis in old-aged patients is concerned, diagnostic methods present little danger. However, a staging-laparotomy in malignant lymphomas is contraindicated. Significant are late-initiated examinations due to uncontemplated haematological illnesses, especially erythropoiesis. Polymorbidity often leads to medicinal polypragmasy especially when several organ specialists are at work and the local practitioner is not carrying out the treatment alone. The results are agranulocytosis and aplastic anaemia. An intensified hemorrhagic diathesis can occur with old age through damage to the functioning of the thrombocytes. An increased preparedness for thrombosis in old age necessitates a fortified thrombosis prophylaxis. Anticoagulants should be used with extreme precaution. In the treatment of haematoblastosis aggressive chemotherapy can be replaced by symptomatic methods with increased old age.

Aged↗
PubMed1983

[Analysis of the prehospitalization period in myocardial infarct].

56 patients with acute myocardial infarction during the period 1973/74, and 58 during the period 1979/80, were questioned immediately after arrival in the coronary care unit about their pre-hospitalization phase. We were able to determine, that the patients' decision time followed by the transportation time accounted for the greater part of the pre-hospitalization period. The contact time between general practitioner and patient played only an insignificant role in the total time-lag. In a comparison of the years 1973/74 and 1979/80 an increase in the patients' decision time and a decrease in the transportation time became evident. Noteworthy was, that in approximately one-fifth of the cases the telephone call to the doctor was not answered. Since an improvement in informing the general public about prodromal symptoms of heart attacks does not seem to bring about a decrease in the decision time, a shortening of the pre-hospitalization period could succeed through a reduction in transportation time and an improvement in doctor accessibility. The use of mobile coronary care units, in particular in rural areas, and improvement in doctors' radio communication services would in that case be matters for discussion.

Coronary Care Units↗
PubMed1978

[Bone scans in the diagnosis of renal osteopathy].

Biochemical tests (serum calcium, inorganic phosphate and alkaline phosphatase), as well as clinical, radiological, scanning and histological investigations were undertaken in 24 patients in chronic renal failure. The frequency with which the diagnosis of renal osteopathy could be made depended in the method of investigation, the biochemical findings proving to be completely unreliable. There were positive radiological signs in ten patients and clinical signs in 12, predominantly in the progressive stages of osteopathy. A positive scan was obtained in 23 patients, typical histological bone changes in an equal number. Since it correlates so well with the histological findings, bone scan is suitable particularly in the early diagnosis of osteopathy. Since this test is easily performed and hardly stresses the patient, it should routinely be the initial one for the diagnosis of renal osteopathy.

Adult↗