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Biomedical subjects

G Mackman

Publications and source records attributed to G Mackman.

2 recordsLinked to original sources

Corneal changes in aniridia.

Nineteen patients with aniridia and one patient with bilateral iris colobomata from eight families were examined for corneal abnormalities. Thirty-six eyes revealed changes that are consistent with a progressive corneal dystrophy. These changes begin in the corneal periphery in the early years of life and progress to the corneal center with increasing age. This dystrophy has been staged into four typical clinical patterns. Central corneal scarring, and in some cases, ulceration may occur, which may be a significant threat to vision.

Adolescent

Delayed sterile keratitis following radial keratotomy successfully treated with conjunctival flap.

BACKGROUND: A case of sterile keratitis involving three adjacent incisions and intervening stroma occurring 5 years after an eight-incision radial keratotomy is reported. METHODS: Multiple cultures showed no pathogens. Treatment with antibiotics, lubricants, patching, and bandage contact lenses failed to improve the condition. A conjunctival bridge flap was therefore performed. RESULTS: Total resolution of the keratitis occurred rapidly after performing the conjunctival bridge flap. CONCLUSIONS: Delayed keratitis following radial keratotomy has been reported in the past. Treatment in these cases has primarily been corneal transplantation. The present case presents an alternative treatment, conjunctival bridge flap, which was successful in this case of sterile keratitis following radial keratotomy.

Adult