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Biomedical subjects

G Mangold

Publications and source records attributed to G Mangold.

At least 19 recordsLinked to original sources

[Surgical treatment of oesophageal carcinoma (author's transl)].

Between 1977 and 1980 55 in-patients were treated for oesophageal carcinoma. Tumour stage and general state permitted curatively aimed treatment in only 19 patients. Combined pre-irradiation and operation were the treatment of choice in these cases. Subtotal oesophageal resection and reconstruction were performed in one session. The stomach was used as replacement organ in all cases. In five cases with cervical or immediate supracardial tumour localisation the oesophagus could be extirpated by bimanual dissection without thoracotomy. Fourteen patients required surgery in both cavities. In nine out of the remaining patients, in whom only palliative surgery could be performed, retrosternal tumour bypass with the stomach was performed. During admission, lasting on average 17 days after the operation in 28 patients, three patients with resection and one with bypass died. In the other 24 patients operation led to normal ability to swallow.

Esophageal Neoplasms

[Percutaneous drainage of the biliary tract by means of a fine needle (author's transl)].

Temporary pre-operative and post-operative as well as permanent palliative percutaneous biliary-tract drainage was performed in 12 patients with biliary tract obstruction; in three the drainage was internal and in nine external. Main indication of the method is permanent palliative decompression in cases of inoperable malignant tumour with obstructive jaundice. Pre-operatively, percutaneous biliary tract drainage serves as a temporary measure in order to perform an operation after decompression of the biliary tract and improving the patient's general condition. The only serious complication was biliary peritonitis after a drainage catheter had slipped out.

Biliary Tract Diseases

[Benign tumors of the liver-diagnosis and therapy (author's transl)].

From 1971 to 1976 surgery was done on 11 patients with benign tumors of the liver in the Surgical Department of the University of Mainz. Histological examinations revealed focal nodular hyperplasia in 5 cases, liver cell adenoma in 2 cases, caverneous hemangioma in 2 cases, cystic liver disease in 1 case, and an idiopatic peritoneal liver cyst in 1 case. Benign tumors of the liver are rare. Clinical symptoms in these cases are inconspicuous. In 5 patients the diagnosis was made coincidentally. Preoperative diagnosis depends mainly on angiography. Since an exact histological diagnosis cannot be made otherwise, surgery is imperative. Big tumors leading to displacement of intestinal or biliary organs ought to be removed in toto; this allows complete histological work up and exclusion of malignancy, and it does prevent recurrence of the tumor as well. In 8 of 11 patients tumors localized peripherally in the liver could be removed surgically without complications.

Adenoma

[Causes and treatment of jaundice associated with inflammatory pancreatic disease (author's transl)].

Jaundice or biliary stasis occurred in 32 of 82 patients with acute and 58 of 152 patients with chronic pancreatitis. A biliary cause was present in only 12 patients with acute and 19 with chronic pancreatitis. In the case of mild acute pancreatitis the cause of the jaundice lay in oedema of the head of the pancreas, while in the severe forms there was necrosis of the head. In chronic pancreatitis the jaundice is caused by tube-like, long stenosis of the choledochal duct or its compression by a cyst within the head of the pancreas. In acute pancreatitis treatment depends on the severity of the inflammation; in the biliary form the biliary tracts are attended to. In chronic pancreatitis resection of the head of the pancreas is preferred, biliodigestive anastomosis being practised if there is likely to be poor cooperation by the patient.

Acute Disease

[Results of resection treatment of chronic pancreatitis (author's transl)].

A total of 201 patients with chronic pancreatitis were treated surgically between 1964 and 1975. In 116 cases (57,7%) resection was done at operation: 44 partial and 18 total duodenopancreatectomies, 37 partial and 17 subtotal left pancreatic resections. The mortality rate of the operation was 12.9%. The late mortality was 9.4% based on an average observation period of 2 7/12 years. Three quarters of the patients became completely asymptomatic. Preoperative diabetes was observed in 21% rising to 38% postoperatively. Satisfactory long-term results were mainly seen after partial duodeno-pancreatectomy and subtotal left resection. However, continued alcohol abuse limits the success rate.

Adult

[Value of diagnostic measures in blunt epigastric trauma with particular reference to peritoneal lavage (author's transl)].

In 95 patients suffering blunt abdominal trauma the diagnostic validity of abdominal exploration, blood pressure, pulse rate, leukocyte count, and hemoglobin was compared with the results of peritoneal lavage for the detection of intra-abdominal bleeding. Classical clinical symptoms alone are not reliable in evaluation of the patient with abdominal trauma, especially if there are associated multiple injuries. Diagnostic peritoneal lavage has the highest accuracy (more than 95%) and an early diagnosis of intraperitoneal bleeding by widespread use of this method improves the prognosis in these patients.

Abdomen