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Biomedical subjects

G Mappes

Publications and source records attributed to G Mappes.

At least 19 recordsLinked to original sources

[Gastric tolerance of different preparations of acetylsalicylic acid in postoperative prevention of thrombo-embolism (author's transl)].

The necessity for thrombosis-prophylaxis is indisputable. The evaluation of our patients over a period of 2 years revealed results compatible with other authors. Due to its thrombocyte desaggregating action, acetyl-salicylic acid was found to have a definite effect on the thrombophilia by inhibiting the thrombocyte adhesiveness in a beginning thrombosis. It was shown that acetylsalicylic acid in combination with glycocoll is apparently superior to microencapsulated acetylic acid in terms of gastric tolerance. In a small number of patients the therapeutic efficiency was investigated and according to the platelets agglutination test, verified. Further investigations are planned in a major series of patients where acetylsalicylic acid with glycocoll was administered in respect to the treatment of rheumatic fever.

Aspirin↗

[Immediate one-stage total oesophagenal replacement by transmediastinal transposition of the stomach without thoracotomy in a case of hypopharyngeal carcinoma (author's transl)].

A case of hypopharyngeal carcinoma (in a 36-year-old man) is reported in which, after blunt dissection of the oesophagus via a posterior mediastinal tunnel without thoracotomy, the stomach was mobilized and its fundus anastomosed to the pharynx at the level of the vallecula. This form of oesophagectomy was first reported in 1936 by Turner for carcinoma of the thoracic oesophagus. Adopting this procedure in cases of carcinoma of the hypopharynx or cervical oesophagus (as recently reported) has as its main advantage the restoration of normal swallowing within a few days, as also took place in the described case.

Adult↗

[Report of a cased of carcinoma of the hypopharynx successfully treated by immediate pharyngogastrostomy (author's transl)].

The treatment of carcinoma of the lower part of the pharynx and upper oesophagus presents many difficulties. One of the outstanding problems being that of repair of the defect after excision of the pharyngo-oesophageal portion of the alimentary tract. This paper describes an operation in which the mobilized stomach is transposed after blunt dissection of the oesophagus via a posterior mediastinal tunnel without thoracotomy to a position high in the neck, with anastomosis of the fundus to the pharynx at the level of vallecula. This type of oesophagectomy was first tried bei Turner 1936 for carcinoma of the thoracic oesophagus. The main advantage of this form of repair is that it can restore normal swallowing within a few days in this difficult clinical situation.

Adult↗