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Biomedical subjects

G Marcuzzo

Publications and source records attributed to G Marcuzzo.

7 recordsLinked to original sources

Helicobacter pylori and luminal gastric pH. Relationships in nonulcer dyspepsia.

The relationships between gastric pH and Helicobacter pylori infection were studied in 37 consecutive subjects affected with nonulcer dyspepsia. Each underwent esophagogastroduodenoscopy with multiple gastric biopsies for both H. pylori and histologic assessment, and 24-hr antral pH monitoring. H. pylori was harbored by 59.5% of the subjects with whole gastric spread of infection in all but one patient. Histologic gastritis was shown in 70.3% of the subjects. H. pylori was strongly associated with gastritis, both antral nonatrophic and multifocal atrophic. The ranges of 24-hr pH values were 1.3-6.9 in the H. pylori-positive and 1.2-6.8 in the H. pylori-negative group. Differences in pH values between the two groups were not significant. Moreover, the mean percent time duration of pH above 2, 4, and 6 did not significantly differ between the two groups. Therefore, this study has shown that chronic H. pylori infection is not related to luminal gastric pH.

Adult

Relationship between mixed acid-alkaline gastroesophageal reflux and esophagitis.

The severity of reflux esophagitis is related to the potency of refluxed material and the duration of its contact with the esophageal mucosa. The occurrence of esophagitis in patients with gastric hyposecretion or even with achlorhydria has focused attention on nonacid gastroduodenal contents. Until analytical studies of refluxed material are available to clarify its composition, the 24-hour combined gastric and esophageal pH monitoring can be used for detecting gastroesophageal reflux and for trying to analyze the composition of the refluxate. The first problem of this investigation was to examine whether the mixed acid-alkaline reflux, defined by pH monitoring, represented reflux of duodenal content; the second to study if there was a correlation between this type of gastroesophageal reflux and esophagitis. Unequivocal grade II and III esophagitis were considered. Our data suggest that the mixed acid-alkaline gastroesophageal reflux represents reflux of duodenal contents into the stomach and successively into the esophagus. The higher incidence of endoscopic-proven esophagitis in patients with mixed acid-alkaline gastroesophageal reflux in comparison to patients with acid gastroesophageal reflux supports the concept that biliary and pancreatic secretions may be a contributory factor in esophageal injury.

Acids

[The occupational risks in a company producing aluminum alloy wheels].

An environmental hygiene study was carried out in a factory making aluminium alloy wheels via pressure moulding. Physical risk factors (noise and microclimate) and chemical risk factors (respirable dust, mineral oils, solvents, fluorides, formaldehyde, CO) were assessed. Analysis of the data showed that physical risk factors were prevalent, whereas chemical pollution was insignificant due to technical improvements made by the management in the course of several redesigns of the plants.

Air Pollutants, Occupational

[Pollution by nitrous dioxide during diagnostic laparoscopy interventions].

Here we have outlined the data relative to an environmental survey carried out in a laparoscopy clinic at the hospital of Padua, to determine the environmental concentration of nitrous dioxide (N2O) used for intra-abdominal inflation during diagnostic laparoscopy interventions. The data obtained have revealed cases of considerable N2O environmental pollution. This above all, due to spontaneous loss of gas during the intervention and to the lack of adequate ventilation systems.

Air Pollutants, Occupational