PubMed Health⌕ Search

Biomedical subjects

G Margolis

Publications and source records attributed to G Margolis.

At least 19 recordsLinked to original sources
PubMed1990

Psychological effects of breast-conserving cancer treatment and mastectomy.

Patients in the early stages of breast cancer were studied one year after treatment to ascertain the psychological effects of mastectomy and a breast-conserving alternative, lumpectomy plus radiation therapy. Patients who had had a mastectomy felt less attractive, less sexually desirable, and more ashamed of their breasts. They also experienced less enjoyment in their sexual relationships than they had before treatment. Patients who had radiation therapy experienced no changes in these areas. For these reasons, half of the mastectomy patients regretted not having chosen the breast-conserving alternative.

Body Image↗
PubMed1990

Improved left ventricular function in myocardial infarction following intravenous thrombolytic therapy with acylated plasminogen activator.

Forty-six patients with acute myocardial infarction (MI) were treated within three hours of the onset of chest pain with an intravenous bolus (IV) of 30 units of anisolated plasminogen activator streptokinase complex (APSAC). Reperfusion was detected in 31 patients (67%) by clinical, electrocardiographic, and enzymatic criteria. The mean time elapsed between the onset of the chest pain to thrombolytic therapy was 114 +/- 53 minutes. Left ventricular ejection fraction (LVEF) was significantly better in patients with anterior and inferior myocardial infarction who had successful reperfusion, as compared with those who did not (48.8 +/- 13.0 vs 35.3 +/- 10.9, p less than 0.05 and 59.7 +/- 12.6 vs 47.9 +/- 15.3, p less than 0.05, respectively). The rate of reocclusion within three weeks was 22%. The overall one-year mortality was 4%. There were no serious adverse reactions following the thrombolytic treatment. Thus bolus IV injection of 30 units of APSAC is both safe and effective in preserving left ventricular function when given early in the course of acute myocardial infarction.

Adult↗
PubMed1986

Working together separately: clarifying the relationship between college therapist and dean of students.

The authors, a college psychotherapist and dean of students, describe the relationship between these college personnel. They describe the dynamics of their interaction and the importance of communication and mutual understanding. They define counseling and therapy, discuss the issues of agency and confidentiality, suggest methods of referral and consultation, and emphasize the need for support and trust within a school community. Finally, they present case studies that illustrate the benefits of mutual trust, understanding, and respect.

Achievement↗
PubMed1982

Bioadhesive and histotoxic properties of ethyl-2-cyanoacrylate.

Ethyl-2-cyanoacrylate was applied to the cortex of rabbits to evaluate its bioadhesive and histotoxic behavior. The animals were killed at 4 or 10 days. Half of the animals were pretreated with dexamethasone. Our results indicate that the application of ethyl-2-cyanoacrylate to brain tissue produced severe superficial cortical necrosis but not bioadhesion. Pretreatment with steroids did not provide a significant protective effect.

Adhesiveness↗
PubMed1978

Reflex vertical gaze and the medial longitudinal fasciculus.

Extraocular movements were investigated in a patient with bilateral vascular lesions of the medial longitudinal fasciculus. The patient showed voluntary and reflex horizontal gaze consistent with his lesion, but had absent reflex vertical gaze. Voluntary vertical gaze was present. Necropsy was performed, and the findings suggest that the medial longitudinal fasciculi in the pons conveys impulses for reflex vertical gaze, but are not required for voluntary vertical gaze.

Brain Mapping↗
PubMed1977

Mycoplasma-like structures in granulomatous angiitis of the central nervous system. Case reports with light and electron microscopic studies.

Two patients had granulomatous angiitis of the central nervous system. The typical vasculitis involved the small branches of the cerebral arteries in both patients and resulted in thrombosis of the left middle cerebral artery in one. Electron microscopy demonstrated structures resembling Mycoplasma organisms. These were present in small numbers in the wall and in the granulomatous reaction within the lumen. Giant cells were observed cintaining particles suggestive of Mycoplasma within the perinuclear cisternae. Virus-like particles were not observed.

Adult↗