Biomedical subjects
Publications and source records attributed to G Markowsky.
A phage typing set composed of 13 phages is described for characterizing Staphylococcus epidermidis. Isolates (372) from cases of bovine mastitis were used in this study. Of these, 350 or 94% were successfully delineated, and 63 phage types were observed. Twenty two cultures were not typeable.
A phage typing set composed of 32 phages is described for differentiating Escherichia coli. Eight hundred sixty-six isolates from cases of bovine mastitis were used in this effort. Of these cultures 829, or 96%, were characterized successfully, and 178 phage types were observed. Thirty-seven isolates were not typable.
This paper summarizes approaches to developing mathematics that can act as a language for immunogenetics. The need for this has been documented by showing inadequacies of the standard symbolism. Apparent distinctions in symbolizing and conceptualizing factors involved in immunogenetics are seen to disappear in the mathematical models presented here. One model, a three-fold Boolean matrix factorization, subsumes all approaches to the idea of specificity and yet is general enough to incorporate data beyond that found only in a reaction matrix.
Mathematical Immunogenetics I argued for the development of mathematics as a language for immunogenetics. A three-fold factorization of a reaction matrix was seen to be the important form of a model of a first order immunogenetic system. In the present paper, results of the authors on determining this factorization are reworked from a physical perspective and presented in an algorithmic form that can be used to compute a labeling matrix from data. Computer programs to perform these computations are in preparation.
A set composed of 27 phages is described for differentiating Salmonella spp. representative of groups A, B, C1, C2, D1, D2, E1, E2, E3, E4, G1, K, and N. All of the 1,245 cultures used in this effort were typable and were differentiated on the basis of the 420 phage patterns observed. All results were reproducible. Characteristic phage patterns were produced by a variety of Salmonella serovars isolated from campus incidents and a number of hospital, family, restaurant, and processing plant outbreaks to indicate an existing epidemiological relationship.