PubMed Health⌕ Search

Biomedical subjects

G Marx

Publications and source records attributed to G Marx.

At least 145 records · Page 8Linked to original sources
PubMed1983

[Surgical experience of cancer of the resected stomach].

The results of surgical treatment of 40 cases of cancer developing in the gastric stump were analysed. 97.5% of patients were operated on; 41% underwent radical surgery and 20.5%--palliative resection. Postoperative mortality in the radical surgery groups was 43.7%, and 50% in the other group. 12.5% of the radically--operated patients survived over 5 years. Moreover, pathogenetic patterns of the disease as well as optimal terms for starting regular postoperative follow-up are discussed.

Aged↗
PubMed1983

[Results of treatment of early stomach cancer].

The results of surgical treatment of 40 patients with early gastric cancer are analysed. 57.5% of patients were operated on. Radical resection was performed in 41% and palliative one--in 20.5% of cases. The mortality rates in the radical surgery and palliative resection groups in postoperative period were 43.7 and 50%, respectively. 12.5% of radically-operated patients survived over 5 years. Pathogenetic forms of cancer developing in the gastric stump as well as optimal terms of the commencement of a regular follow-up are discussed.

Adenocarcinoma↗
PubMed1983

[Contribution on the familial occurrence of malignant testicular tumors].

Eight cases of testis tumors in monozygote twin brothers are described in the bibliography. One case is added here. Nearly at the same age, two twin brothers got a right side embryonal teratocarcinoma. The histories of diseases were approximately identical. The brothers died two years later. The possibility of genetic factors causing or influencing the development of malignant testicular tumors are briefly discussed.

Adult↗
PubMed1982

[A new method for isolated regional perfusion of the liver in vivo. Experimental studies (author's transl)].

The canine liver was isolated from its blood supply and perfused for one hour normothermically be means of a new catheter and a perfusion system consisting of oxygenator, pump and heat-exchanger. Hemodynamic parameters, blood gas analyses, and tissue metabolites were evaluated during experiments. The venous return from the lower body and portal vein (1.113/1min) could be maintained with the catheter system so that the mean systemic arterial pressure was within normal limits. With a perfusion rate through the liver 0,55 ml/min/g and perfusion pressure of 10 cm H2O there was an adequate tissue perfusion; this was also shown by blood gas analyses and tissue metabolite concentrations. Using dye dilution methods the isolation of the liver was tested. This showed a leakage of 6-7% of the total perfusion volume. This new method makes it possible to carry out an isolated, normothermic, liver perfusion for one hour without irreversible tissue damage.

Animals↗
PubMed1982

[Clinical aspects of cancer of the resected stomach].

From 1962 to 1980 54 patients suffering from gastric carcinoma following partial gastrectomy were admitted to the Central Institute for Cancer Research of the Academy of Sciences of the GDR. No surgical therapy was possible in 13 additional cases due to distant metastases. In all patients operated upon a considerable expansion of the tumour could be observed. For an early detection of the carcinoma in the resected stomach a regular prophylactic examination by endoscopy should be practiced.

Aged↗
PubMed1981

The CO2 greenhouse effect and the thermal history of the atmosphere.

The influence of the expected rise of CO2 content in our atmosphere upon terrestrial temperature is uncertain. A significant increase in temperature could be threatening to certain aspects of terrestrial biology. On the other hand, it is a general consensus among paleobiologists that the Earth possessed a CO2 atmosphere in the past billion years, without dramatic temperature variations endangering the continuity of life. In order to clarify this problem, and to contribute to the understanding of the CO2 greenhouse effect on Venus we have computed the absorption spectrum of CO2 for a wide range of atmospheric concentrations. More than 2500 spectral lines of the 15 micron band were taken into account in our line-by-line calculation. We have used an empirical exponential line-shape function at the line edges. Our results agree with the experimental data of F. W. Taylor. The estimated increase in surface temperature does not reach the boiling point of water even for CO2 concentrations thousands of times larger than the present concentrations. Higher energy (>666 cm-1) CO2 bands and/or an increase in atmospheric H2O may, however, amplify the greenhouse effect.

Atmosphere↗
PubMed1981

[Local recurrence of rectal carcinoma after abdomino-perineal resection (author's translation)].

From 1970 to 1974 165 patients suffering from rectal cancer underwent surgery at the Central Institute for Cancer Research of the Academy of Sciences of the GDR. In 112 patients abdomino-perineal excision of the rectum and rectosigmoid was performed for curative purposes. Subsequently local recurrences developed in 28 patients (25%). At the end of the 2nd postoperative year 82% of all patients had recurrences. In most cases only a palliative treatment of the recurrence could be established. From 9 patients with recurrences curatively treated only 3 survived for 5 years.--In a small subgroup of patients with postoperative irradiation a pelvic recurrence could be proved only once, whereas chemotherapy (mostly intraluminal) did not influence the rate of recurrences.--Obviously, early treatment of the primary tumour and local recurrence can be regarded as the only measure for improving the survival rate. It is too early for the evaluation of adjuvant therapy to be determined exactly.

Adenocarcinoma↗
PubMed1981

[Early gastric carcinoma; surgical problems (author's transl)].

In the period from 1965 to 1979 63 patients suffering from early gastric cancer underwent resection, i.e. 7,4% of all resected cases of cancer of the stomach in our hospital. The 3 year survival rate came up to 80%, 5 years survival was 75%. The postoperative mortality rate was less than 5%, since 1975 no postoperative mortality. Distal resection was performed in 74%, gastrectomy in 11%, upper partial resection in 6%, gastrotomy in combination with polypectomy in 9%.

Adult↗
PubMed1981

High risk breast cancer: long-term surgical adjuvant therapy based on predictive tests - preliminary report.

A surgical adjuvant therapy trial was started in 1974, in locoregionally advanced breast cancer. The adjuvant hormonal and cytostatic therapeutic regimen was administered according to the results of predictive tests: estrogen receptor (ER) assay and oncobiogram (group I); in the control group (0) no adjuvant therapy was given until relapse, but tests were performed like in group I. Preliminary results. In a subgroup with adjuvant chemotherapy, using one or more substances according to oncobiogram, with or without hormonal treatment, the treated women did highly-significantly better, compared with the untreated group. No advantage was seen from ovariectomy and/or anabolic steroids, either with or without Cytoxan (Test results: ER +, in vitro not growing tumours). Some doubt exists about the results: resistant, especially in testing cytostatics. This doubt and the rate of tumours, not growing in vitro, limit the use of predictive tests, concerning cytostatics. Further, one has to be cautious in the use of additive hormonal treatment in surgical adjuvant therapy: in some cases stimulation can not be excluded.

Adult↗
PubMed1976

[Meteorotropy of vasomotor cephalea].

During a period of 823 days (from 1st October 1971 to 31st December 1973), attacks of migraine, non-migraine vascular cephalea and cephalea due to other neighbouring disturbances strong enough to affect working capacity were studied in 4 subjects. 2152 pieces of data were collected. 2) Frequency was at a minimum in summer and peaked in spring and autumn. 3) Comparison with meteorological conditions points to a highly significant recrudescence of disturbances in cold, damp weather, and meteorological periodicity independent of biological (circadian) rhythms.

Adaptation, Physiological↗