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Biomedical subjects

G Masterson

Publications and source records attributed to G Masterson.

5 recordsLinked to original sources

Anaerobic power performance and the menstrual cycle: eumenorrheic and oral contraceptive users.

AIM: The purpose of this project was to compare the impact of the menstrual cycle on short-term, high intensity (power) performance in active females who either had normal menstrual cycles (NOC) or who were using oral contraceptives (OC). METHODS: Subjects (7 NOC, 17 OC) completed a Margaria-Kalamen staircase test and a Wingate cycle test on 3 occasions: one for familiarization and the other two trials (random order) during menses (MEN) or luteal (LUT) phase. Phase was documented by urinary luteinizing hormone for the NOC. RESULTS: There were no significant differences between MEN and LUT in the NOC group on the Wingate test (n=7) for any of the following: peak power (P=0.33), peak power per kg body weight (P=0.37), anaerobic capacity (P=0.37), anaerobic capacity per kg body weight (P=0.42), power decline (P=0.36), power decline per kg body weight (P=0.35). Also there were no significant differences in power (P=0.95) for the Margaria-Kalamen test (n=6). There were no significant differences between MEN and LUT in the OC group for any of the following variables calculated from the subjects' performance on the Wingate test (n=17): peak power (P=0.39), peak power per kg body weight (P=0.36), anaerobic capacity (P=0.42), anaerobic capacity per kg body weight (P=0.36), power decline (P=0.57), power decline per kg body weight (P=0.66). Also there were no significant differences in power (P=0.44) for the Margaria-Kalamen test (n=11). CONCLUSIONS: For a moderately active group of women, anaerobic power performance was not influenced by menstrual cycle phase in either NOC or OC users.

Adult↗

Fusobacterium necrophorum-induced sepsis: an unusual case of Lemierre's syndrome.

Classical Lemierre's syndrome is characterized by severe sepsis with metastatic abscess formation in young, previously fit people from a primary head or neck focus. The causative organisms are the anaerobic fusobacteria, most commonly Fusobacterium necrophorum. We describe the evaluation, therapeutic interventions and management of a patient with Lemierre's syndrome who presented in septic shock with multiple organ dysfunction. The patient required immediate interventions including endotracheal intubation and mechanical ventilation, fluid resuscitation, inotropic support, bilateral thoracostomy tube drainage of empyemata and antimicrobial therapy. The unexpected isolation of Fusobacterium necrophorum from blood cultures and empyema fluid necessitated a change of antibiotic regime to provide anaerobic cover. The patient required 4 weeks of intensive support including prolonged antimicrobial therapy, and after a further 2 weeks was discharged home from hospital. This case highlights the need to raise the awareness of 'the forgotten disease': Lemierre's syndrome. Its diagnosis may, as in this case, be confounded by a lack of symptoms of pharyngitis at the time of presentation, and end-organ dysfunction associated with severe sepsis, possibly suggesting an alternative source of infection. As appropriate antibiotics reduce mortality dramatically, clinicians need to be alert to Lemierre's syndrome and include it in the differential diagnosis in young but otherwise healthy patients presenting with severe sepsis.

Adult↗

Unique considerations for the pediatric heart transplant recipient: the role of the school nurse.

Heart transplantation has become an accepted therapy for terminal heart conditions in children. With the increasing incidence of pediatric heart transplantation, school nurses may find cardiac recipients in their schools. The article discusses physical and psychological considerations for managing these students. Among the physical considerations are work capacity, appearance, organ rejection, and infection. The psychological considerations are emotions, cognitive functioning, quality of life, and behavioral concerns. The school nurse is a key resource in informing staff about the unique concerns of pediatric transplant recipients and in ensuring they are integrated into the school setting.

Activities of Daily Living↗