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Biomedical subjects

G Mazzeo

Publications and source records attributed to G Mazzeo.

At least 19 recordsLinked to original sources

Central venous catheters and infections.

The indications to the positioning of central venous catheters (CVCs) are various: parenteral nutrition, chemotherapy, infusion of large amount of fluids or blood products, chronic access for hemodialysis, invasive measurement of hemodynamic variables. Infection is the most important clinical complication associated with the use of CVC, both in terms of incidence and of gravity. Despite the efforts for the optimization of the materials that are more and more biocompatible, the presence of a foreign body in the organism is an ideal substratum for the microbial colonization. The Catheter-Related-Bloodstream-Infections (CRBI) involve a pro-longation of recovery stay, the increase in costs of hospitalization and an increase in morbidity and mortality. The infections are caused by: Staphylococcus aureus and Staphylococcus epidermidis (60%), other bacteria (Enterococ-cus faecalis and Faecium, Pseudomonas aeruginosa; 25%) and among fungi by Candida albicans and Parapsilosis (15%). In order to prevent the CRBI it's important to follow some behavioural norms, both during the positioning of the catheter and in the subsequent assistance to the patient. In case of CRBI it is fundamental to make a sure diagnosis with the positivity for the same pathogen of 2 hemocultures obtained from CVC and from a peripheral vein and then with the microbiological analysis of the tip of the catheter, in order to carry out the specific antibiotic therapy.

Catheterization, Central Venous↗

Critical behavior of the two-dimensional spin-diluted Ising model via the equilibrium ensemble approach.

The equilibrium ensemble approach to disordered systems is used to investigate the critical behavior of the two-dimensional Ising model in the presence of quenched random site dilution. The numerical transfer matrix technique in semi-infinite strips of finite width, together with phenomenological renormalization and conformal invariance, is particularly suited to putting the equilibrium ensemble approach to work. A method by which to extract with great precision the critical temperature of the model is proposed and applied. A more systematic finite-size scaling analysis than in previous numerical studies has been performed. A parallel investigation, along the lines of the two main scenarios currently under discussion, namely, the logarithmic corrections scenario (with critical exponents fixed in the Ising universality class) versus the weak universality scenario (critical exponents varying with the degree of disorder), is carried out. In interpreting our data, maximum care is constantly taken to be open to both possibilities. A critical discussion shows that an unambiguous discrimination between the two scenarios is still not possible on the basis of the available finite-size data.

Journal Article↗

Palliative endoscopic treatment of malignant esophagorespiratory fistula: case report.

The authors report on a case of esophagorespiratory fistula due to squamous carcinoma of the esophagus treated on an emergency basis by endoscopic insertion of an Atkinson prosthesis following dilation of the malignant stenosis with Savary dilators. The authors suggest the endoscopic insertion of a prosthesis as the first approach in the emergency treatment of a malignant esophagorespiratory fistula because of the easiness of the technique, and its low morbidity and mortality rates; furthermore, this procedure relieves digestive and respiratory symptoms rapidly and reduces hospital stay while providing the patient with a better quality of remaining life.

Aged↗

Pleomorphic carcinoma of the gallbladder: report of a case.

The authors report a rare case of primary pleomorphic carcinoma of the gallbladder in a 70-year-old woman. A polypoid tumor protruded into the lumen from the fundus of the gallbladder. Characteristic histologic findings included a general lack of architectural cohesiveness, marked pleomorphism, presence of mononucleated and multinucleated giant cells, extensive necrosis, leukocyte-tumor cell phagocytosis or cannibalism. Immunoreactivity for cytokeratin, carcinoembryonic antigen and epithelial membrane antigen as well as histochemical positivity for mucins demonstrated the epithelial nature of the tumor. The neoplasm behaved aggressively; the patient died of metastases 9 months after the operation.

Aged↗

[Treatment of gastric cancer in the aged].

The A. suggest a modification of Stojanovick primary technique in the treatment of gastric cancer in the elderly. They reviewed pathology of gastric resected patients with exclusion of duodenal transit and they foretell such a technique because of a quicker performance, the scantiness of post-operative complication and, at the end, the complete lack of malabsorption syndromes which are so frequent in gastric resected patients.

Aged↗