[Good expert practice of agriculture in the water protection area].
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Biomedical subjects
Publications and source records attributed to G Meinert.
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In 223 healthy people and patients with obstructive lung diseases we examined the degree of cardiopulmonary exhaustion during two ergometric stress tests (Ergooxytensiometrie [EOT] and submaximal Ergostasetest [ET]). Main purpose of the study was to look for differences between sexes in the degree of exhaustion in relation to the type of stress test, thus clarifying the need of a special EOT-modification for women. Measured parameters were arterial oxygen pressure (pO2a), arterial carbon dioxide pressure (pCO2a), base excess (BE), heart rate, noninvasive blood pressure, Wmax and in ET additionally oxygen intake (VO2max) and oxygen pulse. In EOT men and women showed similar results regarding pressure frequence product in health people as well as in patients. Heart rate in EOT was also similar for men and women clearly below maximal range, amounting around 70% of age related maximal value. For pO2a as main indicator of pulmonary gas exchange we found no differences in healthy people as well as in patients with obstructive lung disease between both ergometric methods, but generally some what higher values in women without clinical importance. A sex related modification of the EOT for the evidence of hypoxemia is not necessary.
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A simple method for registration of the tussicular effect in bronchial challenging is described. The results, obtained in this way, are discussed for their informative value. In bronchial challenging with acetylcholine tussicular reaction in all groups of patients is more frequent than broncho constrictive reaction. Evaluated on clinical defined diagnoses respectively anamnestic date there is a good sensibility of the test (index for sensibility 0.85). Till now the date of specifity are not satisfying. It could be solved only by means of longitudinal studies, if these "false-positive" results have an early diagnostive value with regard to beginning functional disturbances in the airways or if they coincide with diagnostic uselessness of the test.