[When the EU pays everybody makes decisions. Interview by Anders Olsson].
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Biomedical subjects
Publications and source records attributed to G Mellbin.
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Ketoprofen (Kp), given intramuscularly to 15 patients with chronic arthritis on the day after elective joint surgery (13), or during bouts of extreme pain (2), resulted in satisfactory pain relief, and seemed able to replace opiates. A new assay method for plasma Kp, based on gas chromatography/high resolution mass fragmentography is described, which permits determination of Kp even in the presence of probenecid. Kp was rapidly absorbed and peak plasma levels of 10.2 to 18.6 mumol/l were attained within 30 min. Probenecid did not interfere with the elimination of Kp.
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As a contribution to an international pool, chromosomal analysis was carried out on 30 women with anorexia nervosa. The stimulus for this study was that during the last decade nine cases have been described of coincidence between Turner's syndrome and anorexia nervosa. Of the 30 women here examined, all had normal chromosomal constitution.
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