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Biomedical subjects

G Mena

Publications and source records attributed to G Mena.

7 recordsLinked to original sources

[Precut sphincterotomy: efficacy and complications].

BACKGROUND: The use of precut sphincterotomy has been criticized as potentially unsafe. Despite this, a number of tertiary referral center have reported their successful use of this technique to increase the rate of common bile duct cannulation and therapeutic procedures. AIM: To evaluate precut papillotomy and correlate the complication rate. METHODS-PATIENTS AND RESULTS: We performed precut sphincterotomy in 120 patients in whom attempts at standard common bile duct cannulation and sphincterotomy were unsuccessful. Bile duct diameters were correlated to the complication rate. Cannulation of the common bile duct and endoscopic sphincterotomy was successful immediately after precut sphincterotomy in 103 patients (86%), and was successful in 12 of the 17 patients who underwent repeat ERCP, for a total cannulation and sphincterotomy rate of 96%. Eight patients (6.9%) experienced complications: six bleeding, and two retroduodenal perforation. There was no procedure-related mortality, and complications were managed medically except on patient with bleeding who required surgical intervention. CONCLUSIONS: Precut sphincterotomy was effective and safe in facilitating cannulation and sphincterotomy in patients in whom standard cannulation attempts failed. Excluding patients with small duct size may further reduce the complication rate.

Adolescent↗

[Self-expanding metal prosthesis as palliative treatment in esophageal cancer].

BACKGROUND: Current non-surgical or endoscopic therapeutic modalities in esophageal cancer include dilatation, thermocoagulation, injection of alcohol or chemotherapeutic agents, photodynamic therapy, intracavitary irradiation, and placement of plastic or metallic prostheses. None of these procedures, however, has proved to be a simple and well-tolerated like the last one. AIM: Achieve palliation of dysphagia, in patients with nonresectable esophageal cancer treated with a metal self-expanding endoprosthesis. PATIENTS--METHODS AND RESULTS: Twelve patients (6 men and 6 women, mean age 58) with dysphagia caused by non-resectable esophageal cancer were treated with a metal self-expanding endoprosthesis. Prior to treatment, they had mean dysphagia grade of 3.5. Histologic diagnosis was squamous carcinoma in 4 cases, and adenocarcinoma in 8. Six tumors were located at the gastroesophageal junction, 4 in the distal esophagus, and 2 in the mid-esophagus. None of the patients had cervical esophageal tumor. All procedures were performed under mild intravenous sedation. Stent insertion was technically successful in 91.6%, and led to a reduction of dysphagia from a mean score of 3.5 to a mean score of 0.5 at first and 4th weeks. Ninety-one percent of the patients continued to swallow during follow-up (average follow-up: 10.5 weeks, range 1 day-35 weeks). Early complications (within 30 days) included retrosternal pain in 2 patients which resolved in a few days and one patient with recurrent bleeding from the tumor site. CONCLUSIONS: Self-expanding metal stents placement is a relatively simple and atraumatic procedure, it is safe and effective in treatment of malignant dysphagia.

Adenocarcinoma↗

[Endoscopic cholangiopancreatography (ERCP) in pediatric patients].

BACKGROUND: While Endoscopic Retrograde Cholangio-Pancreatography (ERCP) is widely employed in the management of adult pancreaticobiliary disease, its use in children has been limited. AIMS: To evaluate if ERCP diagnostic and therapeutic, is a safe and useful procedure in the diagnosis and treatment of pancreatobiliary disorders in children. PATIENTS, METHODS AND RESULTS: We reviewed our experience with 72 ERCPs performed in 50 children (age 7-17 y, mean 14.5 y). The procedures were performed using standard adult side-viewing duodenoscopes. We used general anesthesia in 25 and conscious sedation in 47. In 38 patients we performed one, in 7/2, in 2/3, in 1/4 and in 2/5 ERCPs. The biliary or pancreatic ducts were successfully cannulated in 98%. Abnormal papilla accounted for the unsuccessful attempt. Abnormalities were found in biliary ducts in 54% and pancreatic duct in 24%, including choledocholithiasis (10), stenosis of the papilla (5), benign biliary stenoses (5), recurrent pancreatitis (4), pancreatic fistula (4), bile duct leak (3), cholelithiasis (3), chronic calcifying pancreatitis (2), pancreas divisum (2) and choledochal cyst (1). Endoscopic sphincterotomy was performed in 19 patients, 15 on biliary segment and four on pancreatic segment. Stents were placed in the biliary duct in nine patients and in pancreatic duct in six patients. Complications included abdominal pain and elevated amylase in three patients (6%), which resolved rapidly. CONCLUSIONS: ERCP in children and adolescents is a safe and underutilized diagnostic and therapeutic procedure.

Adolescent↗

[Benign esophageal strictures in toddlers and pre-school children. Results of endoscopic dilation].

BACKGROUND: The most frequent causes of dysphagia in children are benign strictures and therefore require special consideration. OBJECTIVE: To evaluate safety and efficacy of endoscopic dilation in children with benign esophageal strictures. MATERIAL-METHODS-RESULTS: Twenty four consecutive children of 1.5 to 5.5 years (mean 3.5), with benign esophageal strictures were evaluated in a prospective manner over a 3-year period. The most frequent causes of esophageal stricture were caustic ingestion (Group A) and in Group B were included other benign strictures. Dilation was done on a weekly base using Savary-Gilliard bougies and was considered adequate, if the esophageal lumen could be dilated to 11 mm with complete relief of dysphagia. Of the 24 patients, 16 had corrosive strictures, 6 complications of gastroesophageal reflux and 2 post surgical strictures. Group A required a significantly higher number of session (14.3 +/- 10.84 vs 7.0 +/- 2.94 p: > 0.05), less free-time dysphagia (1.1 +/- 0.39 vs 2.6 +/- 0.95 months p: < 0.01) and a higher number of recurrences (3.12 +/- 1.12 vs 1.25 +/- 0.95 p: < 0.01). Two esophageal perforations occurred during a total of 292 dilation sessions (0.68%). There was one fatality. CONCLUSIONS: Benign esophageal strictures in children can be treated effectively and with acceptable safety by means of endoscopic dilation.

Child, Preschool↗

[Colonic polyps in children. Experience with polypectomy].

BACKGROUND: Colonic polyp, the most common gastrointestinal tumor in children, is considered a cause of rectal bleeding in the pediatric population. Colonoscopy is the "gold standard" procedure in diagnosis and therapeutic. OBJECTIVE: To know the incidence and symptomatology of colonic polyps in children to remark on the usefulness of the endoscopic examination. PATIENTS-METHODS AND RESULTS: Between 1985 and 1996, over 1,000 colonoscopies were performed on 50 children between 8 months and 14 years old. The patients had colonic polyps and lower gastrointestinal bleeding. In 40 cases polyps were solitary, 82% were located in rectum sigmoid, and 80% of polyps were found to be juvenile (retention). There were no complications associated with diagnostic and therapeutic endoscopy. CONCLUSIONS: The endoscopic method was shown to be very useful for diagnosis as well as treatment of the colonic polyps in children.

Adolescent↗